Search results for " dose"

Cumulative radiation CT dose in young traumatic patients: a single centre 5 years retrospective review

2014

Prophylaxis in congenital factor VII deficiency: indications, efficacy and safety. Results from the Seven Treatment Evaluation Registry (STER)

2013

WOS: 000319897700018

126. Dosimetric analysis of phenolic solid state pellets exposed to radio-therapeutic photon and electron beams through electron spin resonance techn…

2018

Abstract Purpose Among the various dosimetric techniques used for characterizing the radiation beams used in radiation therapy, the electron spin resonance (ESR) arouses increasing interest for applications in various therapy procedures. In this work we report the ESR investigation of particular phenol compounds exposed to clinical photon and electron beams [1] . Materials and methods Pellets were produced by mixing Phenol (IRGANOX 1076® Sigma Aldrich) and paraffin (10% by weight). The irradiations of dosimeters were performed with photon and electron beams with absorbed doses ranging from 0 to 13 Gy. Basic dosimetric properties of phenolic dosimeters, such as reproducibility, dose-response…

Response of GAFChromic® HD-V2 film dosimeter in 10-300 Gy dose range for radiation testing of electronic devices

2019

The study reported in this paper aimed to investigate the response of a GAFChromic? HD-V2 film dosimeter in the dose range between 10 and 300 Gy, normally used to perform irradiation tests on electronic devices with a 60Co gamma-ray irradiator. The well-defined linearity of response in terms of absorbance as a function of absorbed dose, easiness of handling and data analysis of irradiated dosimeters, reproducibility, stability, and insensitivity to visible light and most of the environmental parameters, make HD-V2 film a flexible, inexpensive and reliable dose measurement device. The study has shown a fogging effect of the dosimeter response since its value changes over time. Strategies and…

IqYmune® is an effective maintenance treatment for multifocal motor neuropathy: A randomised, double‐blind, multi‐center cross‐over non‐inferiority s…

2018

Intravenous immunoglobulin (IVIg) is the gold-standard for maintenance treatment of multifocal motor neuropathy (MMN). This phase III, randomised, double-blind, multi-centre, active-control, crossover study, aimed to evaluate the non-inferiority of IqYmune® relative to Kiovig®, primarily based on efficacy criteria. Twenty-two adult MMN patients, treated with any brand of IVIg (except Kiovig® or IqYmune®) at a stable maintenance dose within the range of 1 to 2 g/kg every 4 to 8 weeks, were randomised to receive either Kiovig® followed by IqYmune®, or IqYmune® followed by Kiovig®. Each product was administered for 24 weeks. The primary endpoint was the difference between IqYmune® and Kiovig® …

Supplement 2 for the 2004 update of the AAPM Task Group No. 43 Report: Joint recommendations by the AAPM and GEC-ESTRO

2017

Since publication of the 2004 update to the American Association of Physicists in Medicine (AAPM) Task Group No. 43 Report (TG-43U1) and its 2007 supplement (TG-43U1S1), several new low-energy photon-emitting brachytherapy sources have become available. Many of these sources have satisfied the AAPM prerequisites for routine clinical purposes and are posted on the Brachytherapy Seed Registry managed jointly by the AAPM and the Imaging and Radiation Oncology Core Houston Quality Assurance Center (IROC Houston). Given increasingly closer interactions among physicists in North America and Europe, the AAPM and the Groupe Europeen de Curietherapie-European Society for Radiotherapy & Oncology (GEC…

Intermittent Low-Dose IFN Gamma Treatment for Metastatic Renal Cell Carcinoma: Analysis of Factors Predicting Clinical Response and Long-Term Survival

1995

Background: Objective tumor remissions are induced by a variety of immunomodulating agents in a minority of patients suffering from metastasizing renal cell carcinoma. The results of different clinical studies, however, varied greatly for each of these treatment modalities. In order to elucidate potential causes for this variability and to further study the long-term results of intermittent low-dose IFN gamma therapy in patients with advanced renal cell cancer (RCC) we retrospectively analyzed factors predicting clinical response and long-term survival of 121 patients. Material and Methods: We retrospectively analyzed the clinical results of 5 phase II studies treating 121 patients with int…

IFN-gamma-induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations

2007

BACKGROUND: Rhinovirus-induced acute asthma is the most frequent trigger for asthma exacerbations. OBJECTIVE: We assessed which inflammatory mediators were released from bronchial epithelial cells (BECs) after infection with rhinovirus and then determined whether they were also present in subjects with acute virus-induced asthma, with the aim to identify a biomarker or biomarkers for acute virus-induced asthma. METHODS: BECs were obtained from bronchial brushings of steroid-naive asthmatic subjects and healthy nonatopic control subjects. Cells were infected with rhinovirus 16. Inflammatory mediators were measured by means of flow cytometry with a cytometric bead array. Subjects with acute a…

Metabolites of diethylstilboestrol induce sister chromatid exchange in human cultured fibroblasts

1979

Diethylstilboesterol (DES) is one of the few substances for which a clear association with carcinogenicity has been established in man. Nevertheless, it is still widely used, mainly as a cheap oestrogen to increase the slaughter weight of beef, but in spite of this it is not known if residues in the meat or metabolites excreted by the cattle are hazardous to man. It is also unknown whether there is a threshold dose below which DES is harmless. A threshold might be expected if a hormonal mechanism of carcinogensis rather than metabolic activation to an electrophically reactive species operats. This possibility was supported by the observations that DES, in contrast to most other carcinogens,…

SU-FF-T-62: Dosimetric Evaluation of An Internal Shielding Used with a HDR Skin Applicator

2009

Purpose: The Valencia HDR skin applicators are accessories of the microSelectron HDR afterloading system (Nucletron) cup shaped to limit the dose to the irradiation area. Applicators sizes are: diameter 2 and 3 cm. The typical prescription depth is 3 mm. This work aims to evaluate the backscatter and electron contamination of an internal shielding used to reduce the dose to the ocular globe when the lesion is located at the eyelid. Monte Carlo(MC) and experimental methods have been used. Method and Materials: The geometry has been: the Valencia applicator (2 cm diameter) on the surface of a solid polystyrene slab phantom; inside, a 2 mm lead slab located at 3 mm depth. MC simulation charact…