Search results for " drug carrier."

Covalently Modified Halloysite Clay Nanotubes: Smart Nanomaterials for Drug Delivery Applications

2017

Halloysite nanoclays (HNTs) are promising nanomaterials because of their versatile properties, such as hollow tubular morphology and tunable surface chemistry. HNTs are biocompatible, no toxic and abundantly available at low cost. Due to these characteristics HNTs are suitable for development of hybrid sustainable materials, which are perspective for polymeric matrices reinforcement, active food packaging and drug delivery. HNTs are quite polydisperse in size with a length of ca. 1 m, while the external diameter and the lumen range between 50-80 nm and 10-15 nm, respectively. Chemically, halloysite is composed of gibbsite octahedral sheet (Al-OH) groups on the inner surface and siloxane (S…

Covalently modified halloysite clay nanotubes: synthesis, properties, biological and medical applications

2017

Halloysite (HNT) is a promising natural nanosized tubular clay mineral that has many important uses in different industrial fields. It is naturally occurring, biocompatible, and available in thousands of tons at low cost. As a consequence of a hollow cavity, HNT is mainly used as nanocontainer for the controlled release of several chemicals. Chemical modification of both surfaces (inner lumen and outer surface) is a strategy to tune the nanotube's properties. Specifically, chemical modification of HNT surfaces generates a nanoarchitecture with targeted affinity through outer surface functionalization and drug transport ability from functionalization of the nanotube lumen. The primary focus …

Interazioni tra nanotubi e molecole organiche

Nell'ampio scenario dei nanomateriali, i sistemi nanotubolari godono di un consolidato e crescente interesse sia nell'ambito scientifico che industriale. Fra la miriade di sistemi tubolari, i più utilizzati sono i nanotubi a base di carbonio e carbon nanohorns e più recentemente, vista l'elevata biocompatibilità e il loro basso costo, nanotubi inorganici quali i nanotubi di allosite. la funzionalizzazione di questi materiali con diverse tipologie di molecole organiche, ha permesso la sintesi di materiali che potrebbero o hanno trovato applicazione come filler polimerici, come supporti eterogenei in catalisi e nel campo del drug carrier e delivery. Inoltre, nel caso di nanotubi di allosite, …