Search results for " effective"

Work engagement-team performance relationship : shared job crafting as a moderator

2016

The aims of this study were twofold: first, to investigate whether both individual and team work engagement are associated with team members' perceived team performance, and, second, to explore whether shared job crafting within teams moderates the relationship between work engagement and team members' perceived team performance. Data were collected from 1,074 Finnish educational sector employees working in 102 teams. Multilevel analysis revealed that both individual and team work engagement were associated with high levels of perceived team performance. The association between work engagement (both individual and team) and perceived team performance, however, varied across teams. The varia…

Hvordan skapes rom for «omvendt deltakelse» i bærekraftig lokal samfunnsutvikling – aksjonsforskningens roller og bevegelser

2021

Det er økende oppmerksomhet på potensialer for borgeres engasjement i bærekraftig omstilling og lokaliseringen av FNs bærekraftsmål. Flere forsknings- og policyrapporter etterlyser bedre forståelse for hvordan bærekraft kan «oversettes» og implementeres i lokal planlegging og handling. Bærekraftig samfunnsomstilling krever bedre forståelser for hvordan offentlige/kommunale systemer kan samarbeide med borgerinitiativer – samtidig som de lokale initiativene bevarer selvstendighet og lokal forankring. I denne artikkelen tar vi utgangspunkt i en aksjonsforskningsprosess med borgerinitiativer i Oslo og ByKuben, Oslo kommunes senter for byøkologi. Vi utforsker hvordan det kan skapes rom for delta…

Responding to the Spiritual Needs of Palliative Care Patients: A Randomized Controlled Trial to Test the Effectiveness of the Kibo Therapeutic Interv…

2020

Context The WHO recognizes the need to attend to patients' spiritual needs as being fundamental to comprehensive and high-quality end-of-life care. Spiritual needs must be attended since the resolution of biological and psychosocial issues is insufficient to reduce patients' suffering. Associations have been found between spiritual needs and other variables of importance for patients in palliative care. Despite the consensus that exists regarding the importance of assessing and attending to spiritual needs, professionals encounter many difficulties in attempting to do so. Objectives Our study aims to demonstrate the benefits that the KIBO therapeutic interview in palliative care patients ca…

Density distributions in the $B$ meson

2016

We report on a two-flavor lattice QCD study of the axial, charge and matter distributions of the $B$ meson and its first radial excitation. As our framework is the static limit of Heavy Quark Effective Theory (HQET), taking their Fourier transform gives access to several form factors at the kinematical point $q^2=0$. Moreover they provide some useful information on the nature of an excited state, i.e. a radial excitation of a quark-antiquark bound state or a multihadron state.

Usual Care and Informed Consent in Clinical Trials of Oxygen Management in Extremely Premature Infants

2016

Objective The adequacy of informed consent in the Surfactant, Positive Pressure, and Pulse Oximetry Randomized Trial (SUPPORT) has been questioned. SUPPORT investigators and publishing editors, heads of government study funding agencies, and many ethicists have argued that informed consent was adequate because the two oxygen saturation target ranges studied fell within a range commonly recommended in guidelines. We sought to determine whether each oxygen target as studied in SUPPORT and four similar randomized controlled trials (RCTs) was consistent with usual care. Design/Participants/Setting PubMed, EMBASE, Web of Science, and Scopus were searched for English articles back to 1990 providi…

Optimizing diagnostic algorithms to advance Hepatitis C elimination in Italy: A cost effectiveness evaluation

2021

Objectives: Optimized diagnostic algorithms to detect active infections are crucial to achieving HCV elimination. We evaluated the cost effectiveness and sustainability of different algorithms for HCV active infection diagnosis, in a context of a high endemic country for HCV infection. Methods: A Markov disease progression model, simulating six diagnostic algorithms in the birth cohort 1969‐1989 over a 10‐year horizon from a healthcare perspective was used. Conventionally diagnosis of active HCV infection is through detection of antibodies (HCV‐Ab) detection followed by HCV‐RNA or HCV core antigen (HCV‐Ag) confirmatory testing either on a second sample or by same sample reflex testing. The …

PO-0096 Clinical Effectiveness Of Idursulfase In Boys Aged 0–5 Years With Hunter Syndrome: 3-year Data From The Hunter Outcome Survey

2014

Background and aims Symptoms of Hunter syndrome typically become apparent at 2–4 years of age. Previous analyses have demonstrated improvements in certain clinical measures in young patients receiving idursulfase (Shire); however, data on long-term idursulfase use in these patients remain limited. This analysis used data available in the Hunter Outcome Survey (HOS), a global, observational registry sponsored by Shire, to investigate long-term effectiveness of idursulfase in boys with Hunter syndrome aged 0–5 years. Methods As of January 2014, 260/564 males followed prospectively in HOS had received ≥1 idursulfase infusion (excluding those who had received a bone marrow transplant or were en…

2019

Background Congenital Toxoplasmosis (CT) can have severe consequences. France, Austria, and Slovenia have prenatal screening programs whereas some other countries are considering universal screening to reduce congenital transmission and severity of infection in children. The efficiency of such programs is debated increasingly as seroprevalence among pregnant women and incidence of congenital toxoplasmosis show a steady decrease. In addition, uncertainty remains regarding the effectiveness of pre- and postnatal treatments. Method To identify cost-effective strategies, prenatal and neonatal screenings were compared using a decision-analytic model based on French guidelines and current knowled…

Cost-Effectiveness Analysis: Stress Ulcer Bleeding Prophylaxis with Proton Pump Inhibitors, H2 Receptor Antagonists

2012

Abstract Objectives Proton pump inhibitors (PPIs) and H2-receptor antagonists (H2RAs) present varying pharmacological efficacy in preventing stress ulcer bleeding (SUB) in intensive care units. The literature also reports disparate rates of ventilator-assisted pneumonia (VAP) as side effects of these treatments. We compared the cost-effectiveness of these two prophylactic pharmacological options. Methods We constructed a decision tree with a 60-day time horizon for patients at high risk for developing SUB, receiving either PPIs or H2RAs. For each treatment strategy, patients could be in one of three states of health: SUB, VAP, or no complication. Contemporary, clinically relevant probabilit…

Effectiveness of mRNA COVID-19 Vaccination on SARS-CoV-2 Infection and COVID-19 in Sicily over an Eight-Month Period

2022

In order to reduce the spread of SARS-CoV-2 infection and the burden of disease, since 27 December 2020, Sicily has introduced a regional COVID-19 vaccination campaign. This study aimed at estimating the effectiveness of mRNA COVID-19 vaccines on SARS-CoV-2 infections and COVID-19. A retrospective cohort study was carried out on 3,966,976 Sicilian adults aged 18 years or more, who were followed-up from 1 January 2021 to 30 September 2021. The risk of SARS-CoV-2 infection, severe COVID-19, and COVID-19 death or intubation during the study period was compared among vaccinated with two mRNA doses and unvaccinated individuals. Cox regression, adjusted for age and sex, and a joint-point analysis…