Search results for " effects"
showing 10 items of 2364 documents
Intellectual Structure of the Belt and Road Initiative Research: A Scientometric Analysis and Suggestions for a Future Research Agenda
2020
China’s Belt and Road Initiative (BRI) has attracted increasing attention worldwide since its inception in 2013. Although the research is fast increasing in terms of publications, there is a lack of knowledge about the intellectual structure, research trends, and appropriate theories underpinning. Using bibliometric data from 1583 articles from 2013 to 2019 in the Web of Science and Scopus databases, we used bibliometric techniques and scientometric analyses to identify and analyze the intellectual structure, hotspots, and emerging trends in this field. We identified 18 clusters that we categorized into three groups for thematic discussion. Research gaps and future research directions were …
The Sea Urchin sns5 Insulator Protects Retroviral Vectors From Chromosomal Position Effects by Maintaining Active Chromatin Structure
2009
Silencing and position-effect (PE) variegation (PEV), which is due to integration of viral vectors in heterochromatin regions, are considered significant obstacles to obtaining a consistent level of transgene expression in gene therapy. The inclusion of chromatin insulators into vectors has been proposed to counteract this position-dependent variegation of transgene expression. Here, we show that the sea urchin chromatin insulator, sns5, protects a recombinant gamma-retroviral vector from the negative influence of chromatin in erythroid milieu. This element increases the probability of vector expression at different chromosomal integration sites, which reduces both silencing and PEV. By chr…
Effect of solvents on the selectivity of terbutylazine imprinted polymer sorbents used in solid-phase extraction
2002
A solid-phase extraction sample preparation method using a molecularly imprinted polymer (MIP) selective for the triazine type pesticide terbutylazine has been developed. The method involves preconcentration from large volumes of water samples on a C18 disk coupled to selective clean-up on the MIP. The method has been optimised by studying the recovery and retention of terbutylazine and some other structurally related triazine derivates as a function of the selective washing solvent used. The effect of the water content of the selective washing solvent was also investigated on the recovery of the MIP. River water samples were analysed with the coupled technique, and efficient clean-up of th…
Pairing energy effects in cyanide complexes of CpCrIII
1999
International audience; The steric and electronic factors responsible for the reactivity differences between CN and Cl complexes of CpCrIII were examined by DFT/B3LYP computational techniques. The energy difference between quadruplet and doublet [CpCr(CN)2(PH3)], ΔED–Q, was calculated to be 21.2 kcal mol−1 with the LanL2DZ basis set. Although the high-spin configuration is still the ground state for the cyanide complex, the energy gap is 8.7 kcal mol−1 less than that found for the corresponding chloride species. The difference between quadruplet [CpCr(CN)2(PH3)] and doublet [CpCr(CN)2(PH3)2] less free PH3, ΔECr–P, is also smaller than for the Cl system. The components of ΔECr–P for CN and C…
Inherited semisterility for control of harmful insects. I. Productions of semisterility due to translocation in the mosquito,Culex pipiens L., by X-r…
1971
In Anbetracht der theoretischen und in einem Freilandexperiment bereits erwiesenen Moglichkeit der Bekampfung von Schadinsekten durch Freilassung semisteriler Tiere wurde die Produktion von Translokationen und damit verbundener Semisterilitat bei der StechmuckeCulex pipiens untersucht. Die Totalrate der erzeugten Translokationen liegt bei Stechmucken im Vergleich zuDrosophila auffallend hoch. Es besteht offenbar eine Korrelation zwischen der Gesamtlange der Chromosomen und der Translokationsrate.
The Sustainability of Reclaimed Asphalt as a Resource for Road Pavement Management through a Circular Economic Model
2019
The transition of the road engineering industry to a circular way of doing business requires more efficient and sustainable resources, energy, and waste management. The rates in which reclaimed asphalt is being recycled or reused in the asphalt mixture production process constitutes a crucial parameter in this transition. This paper aims at establishing a further step towards the combined circularity and sustainability of asphalt pavements, by introducing a framework for quantifying their Material Circularity Index. The framework is based on the methodology proposed by the Ellen MacArthur Foundation and accordingly tailored for the context of asphalt pavements. This study, thus, attempts to…
European National Road Authorities and Circular Economy: An Insight into Their Approaches
2020
The pavement engineering industry, having realized the significance of the impacts that it imposes on the environment through the production, construction and management of its products and assets, has been driven towards a more sustainable and circular way of operating. This has partly been through asphalt recycling, which is an area that many road authorities have prioritized. However, not all the National Road Authorities (NRAs) and/or sector stakeholders seem to be adequately familiar with the Circular Economy (CE) concept. This paper attempts to assist the transition of NRAs to a more circular way of doing business, by analyzing the current situation of CE within national/regional auth…
Metabolic effects of sacubitril/valsartan: are they relevant in clinical practice?
2018
The burden of cardiometabolic diseases continues to rise worldwide (1). Obesity, insulin resistance, atherogenic dyslipidemia, hypertension and intra-abdominal adiposity are strongly interrelated and are crucial determinants of heart failure (HF) (2).
Plant facilitation and phylogenetics
2013
The relationship between facilitation and evolutionary ecology is poorly understood. We review five issues elucidating how the phylogenetic relatedness of species provides insight into the role of facilitation in community assembly: (a) Are the facilitative interactions more common between species that differ in a regeneration niche? (b) Are facilitative interactions more common between distantly related species? (c) Do communities governed by facilitation (rather than competition) have higher phylogenetic diversity? (d) As facilitated juvenile plants mature, do they compete with their nurses more often if they are closely related to them? (e) How does the phylogenetic signature in a commun…
Prepulse Inhibition of the Startle Reflex as a Predictor of Vulnerability to Develop Locomotor Sensitization to Cocaine
2020
Prepulse inhibition (PPI) of the startle reflex is a measure of sensory-motor synchronization. A deficit in PPI has been observed in psychiatric patients, especially those with schizophrenia and vulnerable subjects, since the neural bases of this disorder are also involved in the regulation of PPI. Recently, we have reported that baseline PPI levels in mice can predict their sensitivity to the conditioned reinforcing effects of cocaine in the conditioned place preference (CPP) paradigm. Mice with a low PPI presented a lower sensitivity to the conditioned rewarding effects of cocaine; however, once they acquired conditioned preference with a higher dose of the drug, a more persistent associa…