Search results for " envelope"
showing 10 items of 253 documents
On the Correlation and Ergodic Properties of the Squared Envelope of SOC Rayleigh Fading Channel Simulators
2012
Published version of an article in the journal: Wireless Personal Communications. Also available from the publisher at: http://dx.doi.org/10.1007/s11277-011-0493-2 In this paper, we investigate the correlation and ergodic properties of the squared envelope of a class of autocorrelation-ergodic (AE) sum-of-cisoids (SOC) simulation models for mobile Rayleigh fading channels. Novel closed-form expressions are presented for both the ensemble and the time autocorrelation functions (ACFs) of the SOC simulation model’s squared envelope. These expressions have been derived by assuming that the SOC model’s inphase and quadrature (IQ) components have arbitrary autocorrelation and cross-correlation pr…
Signal sequences modulate the immunogenic performance of human hepatitis C virus E2 gene
2005
Abstract Envelope protein E2 of human hepatitis C virus (HCV) is an attractive component of a prototype HCV vaccine. Delivered by DNA immunogens, E2 evokes specific immune response of Th1-type, failing to induce either considerable antibody production, or T-helper cell proliferation. We aimed at modulating the immunogenic performance of E2 gene by changing the mode of protein expression in eukaryotic cells. Plasmids were constructed encoding full-length E2 and nonstructural protein 1 (p7) fused to either 13 or 38 C-terminal amino acids (aa) of HCV E1 that contain second hydrophobic segment of E1 stop-transfer signal, or a complete E1 stop-transfer signal with duplicated second hydrophobic s…
Cytoplasmic Parvovirus Capsids Recruit Importin Beta for Nuclear Delivery
2019
Parvoviruses are an important platform for gene and cancer therapy. Their cell entry and the following steps, including nuclear import, are inefficient, limiting their use in therapeutic applications. Two models exist on parvoviral nuclear entry: the classical import of the viral capsid using nuclear transport receptors of the importin (karyopherin) family or the direct attachment of the capsid to the nuclear pore complex leading to the local disintegration of the nuclear envelope. Here, by laser scanning confocal microscopy and in situ proximity ligation analyses combined with coimmunoprecipitation, we show that infection requires importin β-mediated access to the nuclear pore complex and …
Cell Envelopes of Methanogens
2010
Methanogens play an important role in the global carbon cycle, because they are involved in the last step of anaerobic degradation of organic material to methane. Although the first report on methane emanation from aquatic muds was given by Alessandro Volta in the year 1776, the first methanogen was not obtained in pure culture before 1947. Special culture techniques had to be developed for growing the strict anaerobic methanogenic isolates. The methanogens were the first species of the archaeal domain (Archaea) detected. Their unique biochemical and genetic properties have stimulated basic investigations of this microbial group in the last three decades. The methanogenic Archaea possess a …
Technological and behavioral aspects of perforated building envelope in the Mediterranean region
2015
Perforated building envelope presents a global contemporary architectural trend which is connected – in some circumstances – to the traditional perforated models, such as ‘Mashrabiyya’, ‘Takhtabush’, ‘Qmariyyah’, etc. This study focuses on perforated models that have archetypical perforated elements within buildings and have technological and behavioural functions reflecting socio-cultural values, economic situation, and environmental needs of the building’s users. An analytical comparison (technologically and behaviourally) has been conducted between the selected contemporary cases of perforated buildings and the traditional models, by considering various aspects of the building’s envelope…
The role of technological culture in the theoretical dichotomy between technique and form/Il ruolo della cultura tecnologica nella dicotomia teorica …
2017
La cultura tecnologica spiega il rapporto tra forma e tecnica basandosi su una dimensione concreta ed esistenziale. «La dimensione esistenziale “verità” si manifesta attraverso la storia, ma il suo significato trascende la situazione storica. Tale concretizzazione dipende in genere dal come siano le cose fatte, ossia dalle forme e dalla tecnologia» (Schulz, 1979). In tal ottica il saggio esplora teorie e prassi della cultura tecnologica sul rapporto tra materia e forma e tra architettura e tecnica, a partire dal concetto di tecnologia: dall’evoluzione storica delle tecniche e dei sistemi costruttivi al valore dell’innovazione, sondando nelle problematiche ideologiche, sociali e materiali ch…
Cell Wall Structures of Mesophilic, Thermophilic and Hyperthermophilic Archaea
2006
Green Roofs as Effective Tools for Improving the Indoor Comfort Levels of Buildings—An Application to a Case Study in Sicily
2020
In the line of pursuing better energy efficiency in human activities that would result in a more sustainable utilization of resources, the building sector plays a relevant role, being responsible for almost 40% of both energy consumption and the release of pollutant substances in the atmosphere. For this purpose, techniques aimed at improving the energy performances of buildings&rsquo
Reduction Of Pulmonary Inflammation Through HIV-1 Envelope Protein GP120 In A Humanized Mouse Model Of Allergic Asthma Depends On Regulatory T Cells
2011
Characterization of the DNA-binding activity of the E1 and E2 proteins and the E1/E2 complex of human papillomavirus type 33.
1997
The E1 and E2 proteins of papillomaviruses are essential for the initiation of viral DNA replication. We have purified the E2 protein of human papillomavirus type 33 (HPV-33) by immunoaffinity chromatography. The purified E2 protein bound with high affinity to all four consensus binding sites of HPV-33 (Kd approximately equal to 2 x 10(-10)M). A putative E2 binding site differing at one position in the second stem of the palindrome was not bound by E2. The E1 protein of HPV-33 purified by affinity chromatography using glutathione S-transferase as tag displayed specific DNA-binding activity in footprint analyses protecting HPV-33 nucleotides 7896 to 7909/1 to 18 from DNasel digestion. Hypers…