Search results for " evaluation."
showing 10 items of 1351 documents
COX-2 expression in chondrosarcoma: A role for celecoxib treatment?
2010
Chondrosarcomas are resistant to conventional chemo- and radiotherapy. A subset of chondrosarcomas arises secondarily in the benign tumour syndromes enchondromatosis (EC) and multiple osteochondromas (MO), and prevention of tumour development would greatly improve prognosis. We therefore investigated the effect of selective COX-2 inhibition on chondrosarcoma growth. COX-2 expression was studied in central- and peripheral cartilaginous tumours. The effect of COX-2 inhibition was assessed in four high-grade chondrosarcoma cell lines using celecoxib and NS-398 treatment. COX-2 activity (prostaglandin E-2 (PGE(2)) ELISA) and cell viability were measured. The (prophylactic) effect of celecoxib o…
The PROMISE study protocol: a multicenter prospective study of process optimization with interdisciplinary and cross-sectoral care for German patient…
2021
Background and purpose — Knee and hip replacement are common and increasing procedures, and an optimized care process that could be implemented in different settings would be useful. The PROMISE trial investigates whether a new care process works equally in different German settings and how the results compare with current non-standardized care. Patients and methods — This multi-center prospective mixed-method study includes 2,000 German patients receiving arthritis-related hip or knee endoprostheses. An interdisciplinary and cross-sectoral care process was developed and implemented in 3 German hospitals with different levels of care, and corresponding rehabilitation centers were included t…
Treatment with a CO-releasing molecule (CORM-3) reduces joint inflammation and erosion in murine collagen-induced arthritis.
2008
Contains fulltext : 70589.pdf (Publisher’s version ) (Closed access) OBJECTIVE: CO-releasing molecules (CO-RMs) are a novel class of anti-inflammatory agents. We have examined the possible therapeutic effects of CORM-3 in collagen-induced arthritis (CIA). METHODS: Arthritis was induced in DBA-1/J mice by type II collagen. Animals were treated with CORM-3 (5 and 10 mg/kg/day, intraperitoneally) or the inactive compound iCORM-3 (10 mg/kg/day, intraperitoneally) unable to release CO, from days 22 to 31. Production of anti-type II collagen antibodies, cytokines and cartilage olimeric matrix protein (COMP) was evaluated by enzyme-linked immunosorbent assay, and prostaglandin E(2) (PGE(2)) by rad…
Struggles for moral value and the reproduction of gendered and racialised hierarchies in online discussions of violence
2019
The article examines online discussions in Finland that focus on violence committed by Finnish women, on one hand, and non-white migrant men, on the other. Drawing on the perspective of sociology of value, the article illustrates how these discussions function as sites of struggles over moral worth in a contemporary context characterised by crises of both male and white hegemony. The authors suggest that, through the discussions, these current crises are projected on migrant men and certain groups of women, who thereby become construed as morally reprehensible. The analysis sheds light on processes of (re-)legitimating the moral virtue historically attached to both masculinity and whitenes…
Mācību materiālu izveide militārās angļu valodas apguvēju mutvārdu saziņas veicināšanai
2019
Speciālo nozaru angļu valoda ir pieprasīta dažādu jomu speciālistu vidū, jo sniedz iespēju apgūt profesionālo angļu valodu. Šī pētījums mērķis bija noteikt militārās angļu valodas apguvēju individuālās valodas vajadzības un izveidot mācību materiālus, kas veicinātu viņu mutvārdu saziņu. Mācību materiāli tika izstrādāti, izmantojot uz uzdevumiem balstītu metodoloģiju, kas nodrošina valodas apguvi, izmantojot jēgpilnus uzdevumus, atbilstošus komunikatīvus vingrinājumus, lai veicināti valodas funkciju apguvi, kas nepieciešamas, lai attīstītu valodu tās lietojumam reālās situācijās. Pētījuma dati tika iegūti, izmantojot anketas, nodarbību novērošanu, un progresa testus, kas tika rūpīgi analizēt…
Performance Evaluation for a Sustainable Supply Chain Management System in the Automotive Industry Using Artificial Intelligence
2020
Increasing the sustainability of a system can be achieved by evaluating the system, identifying the issues and their root cause and solving them. Performance evaluation translates into key performance indicators (KPIs) with a high impact on increasing overall efficacy and efficiency. As the pool of KPIs has increased over time in the context of evaluating the supply chain management (SCM) system&rsquo
MALE VIOLENCE AGAINST WOMEN: INTEGRATION BETWEEN PSYCHOLOGICAL AND NEUROSCIENTIFIC DATA AND THEIR USE IN FORENSIC EVALUATION FOR THE JUDGMENTS
2020
Human growth and development, starting from conception, are characterized by a progressive increase in body and organ dimensions, as well as specific functional maturity, under the influence of genetic as well as environmental and epigenetic determinants. Beyond a possible normal familial trait, increased fetal growth resulting in a large for gestational age newborn, isolated macrosomia or that associated with congenital malformation, can be attributable to both maternal metabolic and genetic pathology. Overgrowth syndromes are a heterogeneous group of diseases characterized by excessive tissue development often concomitant to neurodevelopmental involvement. Recently, an increased risk of f…
Le attività all’interno del progetto: il workshop. Gestione del campus universitario di Palermo e dell’Edificio 14 Facoltà di Architettura - The acti…
2010
Verificata la mancanza di attenzione alla prevenzione e riabilitazione sismica degli elementi non strutturali nella ricerca scientifica e nella normativa tecnica italiana, è stato avviato un progetto di cooperazione internazionale tra l’Università di Palermo e l’Università di Berkeley dal titolo “Prevenzione e riabilitazione sismica nonstrutturale.Confronto fra due culture di prevenzione sismica al fine di redigere linee guida per un manuale d’uso degli edifici scolastici”, finanziato nell’ambito del programma CoRI 2005/2006 dell’Ateneo di Palermo. Tra le varie attività previste durante la permanenza del partner straniero a Palermo è stato organizzato un workshop, che ha visto coinvolto un …
Loneliness, subjective health complaints, and medicine use among Finnish adolescents 2006-2018.
2022
Aims: Loneliness is an important public health challenge for all ages. This study reports time trends of loneliness among adolescents over a 12-year period and analyses the strength of the associations between loneliness, health complaints, and medicine use. Methods: Data were derived from the cross-sectional Finnish Health Behaviour in School-aged Children study conducted in 2006, 2010, 2014, and 2018. The study population is based on a random sample of schools with 20,444 participants aged 11–15 years. The trends were analysed with a Mantel–Haenszel test, and the strength of the associations was evaluated by mixed-effects logistic and linear regressions. Results: An increasing prevalence …
One minute papers: rendiment i satisfacció de l'alumnat
2014
El procés de millora d'ensenyament- aprenentatge en el context universitari ha generat l'aplicació de noves o millorades tècniques docents, les quals fomenten una participació activa de l'alumne i una major interacció amb el professor. L'objectiu d'aquest treball ha estat analitzar el grau de satisfacció de l'alumnat universitari amb una de les innovacions docents més populars, sobretot, pel seu baix cost i senzillesa, que és el one minute paper, la qual va registrar una alta taxa de participació en el context analitzat. En particular, aquesta experiència docent es va fer en una assignatura de comptabilitat en el Grau d'Administració i Direcció d'Empreses de la Universitat de Santiago de Co…