Search results for " evaluation."
showing 10 items of 1351 documents
A multi-criteria evaluation system for arable land resource assessment
2020
This study proposed a multi-criteria evaluation system for arable land resources by combining the soil integrated fertility index (IFI) with a soil cleanliness index (based on heavy metals and metalloid content). A total of 16 typical arable land units in Chongming District, China, were evaluated using the proposed evaluation system based on 104 collected soil samples in 16 towns. The comprehensive soil evaluation scores of arable lands in 16 towns were in the range of 90.7 to 99.2 with a mean of 96.2, indicating that the arable land in all 16 towns was at the level of excellent (≥ 90.0). Lower cleanliness indices had a significant impact on the final evaluation score. In comparison with si…
Determination of major human cytochrome P450s activities in 96-well plates using liquid chromatography tandem mass spectrometry.
2007
At the early stage of drug discovery, thousands of new chemical entities (NCEs) may be screened before a single candidate can be identified for development. Evaluation of the effect of NCEs on human CYP450 enzyme activities is a key issue in pharmaceutical development as it may explain inter-subject variability, drug-drug interactions, non-linear pharmacokinetics and toxic effects. A liquid chromatography tandem mass spectrometry (HPLC-MS/MS) method has been developed for the fast and routine analysis of major human CYP450s enzyme activities (CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP2E1 and CYP3A4) in primary hepatocyte cell cultures. The high sensitivity and selectivity of mass …
Past and Future: The Urban Landscape and the Virtuous Management of Resource Flows for a Sustainable Environment
2022
A circular process in the case of resource flows can best be expressed according to a plan that takes into account the geographical proximity and synergy between citizens and industries. The study hypothesizes the possibility of anticipating part of the recycling processes in residential urban areas. This streamlines the work phases and consumers become an active part of the process. Circular management of resource flows is an operational problem that emerges with greater severity in an urban landscape, due to the constraints generated by road networks and the need to protect basic values. It often happens that the degradation generated by the irresolute nature of the technical environmenta…
Strategies to In Vitro Assessment of Major Human CYP Enzyme Activities by Using Liquid Chromatography Tandem Mass Spectrometry
2008
At the early stage of drug discovery, thousands of new chemical entities (NCEs) may be screened before a single candidate can be identified for development. Determining the role of CYP enzymes in the metabolism of a compound and evaluating the effect of NCEs on human CYP activities are key issues in pharmaceutical development as they may explain inter-subject variability, drug-drug interactions, non-linear pharmacokinetics and toxic effects. Reliable methods for determining enzyme activities are needed to characterize an individual CYP enzyme and to obtain a tool for the evaluation of its role in drug metabolism in humans. Different liquid chromatography tandem mass spectrometry methodologi…
An empirical comparative evaluation of gestUI to include gesture-based interaction in user interfaces
2019
[EN] Currently there are tools that support the customisation of users' gestures. In general, the inclusion of new gestures implies writing new lines of code that strongly depend on the target platform where the system is run. In order to avoid this platform dependency, gestUI was proposed as a model-driven method that permits (i) the definition of custom touch-based gestures, and (ii) the inclusion of the gesture-based interaction in existing user interfaces on desktop computing platforms. The objective of this work is to compare gestUI (a MDD method to deal with gestures) versus a code-centric method to include gesture-based interaction in user interfaces. In order to perform the comparis…
Cognitive impairment in relapsing-remitting multiple sclerosis can be predicted by imaging performed several years earlier.
2007
Cognitive deficits in multiple sclerosis (MS) are common and correlate with contemporary MRI brain abnormalities, particularly atrophy, but the ability of imaging early in the disease to predict later cognitive impairment remains to be determined. Thirty relapsing—remitting MS patients recruited within three years of the onset of the disease, and in whom MRI had been performed at baseline and a year later, were assessed neuropsychologically five years later. Imaging parameters accounting for significant variance in cognitive performance were identified using multiple regressions, once confounding variables were controlled. Patients performed significantly worse than expected on tests of at…
Learning Motivation and Activity Contexts
1994
Abstract Learning motivation has a special explanatory status in educational psychology and educational practice. Motivation and learning often are studied separately. In the achievement motivation tradition, achievement situation is the connecting link between learning process and achievement need. The explanatory power of this link has limitations. The activity concept is proposed as a unit which is able to offer a broader basis for a unified concept of learning motivation.
Mirror neurons : physiological requirement for emotional empathy and social and moral behaviour of human and nonhuman primates
2018
Fil: Claramonte Sanz, Vicente. Universitat de València. Departament de Filosofia. Área de Lògica i Filosofia de la Ciència; España. Claramonte Sanz, V. (2018). Las neuronas espejo: presupuesto fisiológico de la empatía emocional y de las conductas sociales y morales en primates humanos y no humanos. Metatheoria, 8(2), 15-22. A partir de la evidencia científica y los análisis debidos a los estudios de investigadores como Rizzolatti, Sinigaglia, Galle-se, Goldman, Iacoboni, etc., este artículo argumenta que el vínculo entre neuronas espejo y empatía emocional resulta corroborado por los estudios de Neurociencia sobre la actividad perceptiva y las reacciones emocionales. En particular, con las…
Controlling reactive aggression through cognitive evaluation of proactive aggression cues
2006
The authors investigated how the relationship between the acts of proactive and reactive aggression was moderated by the individual differences in cognitive regulation of emotion. An aggression paradigm, a electrocardiogram recording, a cognitive assessment battery, and a short form IQ test were completed by 109 children, aged 8 to 13 years (Juujarvi, Kaartinen, Laitinen, Vanninen, & Pulkkinen, 2006; Juujarvi, Kooistra, Kaartinen, & Pulkkinen, 2001; Lehto, Juujarvi, Kooistra, & Pulkkinen, 2003). The less the children subdued the intensity of their defence to the attacks in the aggression paradigm, the poorer they performed in the cognitive assessment battery tasks measuring Working memory c…
A framework to identify primitives that represent usability within Model-Driven Development methods
2014
Context: Nowadays, there are sound methods and tools which implement the Model-Driven Development approach (MDD) satisfactorily. However, MDD approaches focus on representing and generating code that represents functionality, behaviour and persistence, putting the interaction, and more specifically the usability, in a second place. If we aim to include usability features in a system developed with a MDD tool, we need to extend manually the generated code. Objective: This paper tackles how to include functional usability features (usability recommendations strongly related to system functionality) in MDD through conceptual primitives. Method: The approach consists of studying usability guide…