Search results for " evaluation."
showing 10 items of 1351 documents
The baculovirus display technology--an evolving instrument for molecular screening and drug delivery.
2008
High throughput screening is a core technology in drug discovery. During the past decade, several strategies have been developed to screen (poly)peptide libraries for diverse applications including disease diagnosis and profiling, imaging, as well as therapy. The recently established baculovirus display vector system (BDVS) represents a eukaryotic screening platform that combines the positive attributes of both cell and virus-based display approaches, allowing presentation of complex polypeptides on cellular and viral surfaces. Compared to microbial display systems, the BDVS has the advantage of correct protein folding and post-translational modifications similar to those in mammals, facili…
L’architettura gotica in Sicilia centro-orientale nelle perizie degli architetti d’età moderna
2018
L’ARCHITETTURA GOTICA IN SICILIA CENTRO-ORIENTALE NELLE PERIZIE DEGLI ARCHITETTI D’ETÀ MODERNA Il contributo si concentra sulla percezione e sulla valutazione da parte degli architetti siciliani d’età moderna di opere costruite sull’isola in età gotica. L’occasione del confronto emerge soprattutto dalle perizie redatte durante l’elaborazione di nuovi progetti (di ammodernamento, di completamento) che contemplano la salvaguardia o la distruzione delle strutture del passato. Le relazioni selezionate in questa occasione affrontano pertanto questioni di carattere prevalentemente estetico e di linguaggio, ma anche le ragioni inerenti alle strutture e quelle relative alle economie (di cantiere, d…
Assessing Effects of eGovernment Initiatives Based on a Public Value Framework
2012
Published version of a chapter in the book: Electronic Government. Also available from the publisher at: http://dx.doi.org/10.1007/978-3-642-33489-4_21 Assessing effects of eGovernment initiatives is considered an important but challenging endeavor. Assessments are, among other things, important to justify e-government investments. They are challenging because they are complex, often based on locally defined indicators, many times over-emphasizing financial effects, imprecise, faced with a number of contingencies and very seldom validated. Consequently, effect assessments can be seen as imprecise and difficult to compare across different initiatives. This paper addresses some of the challen…
Análisis de las calificaciones compartidas en la modalidad participativa de la evaluación colaborativa entre docente y estudiantes
2020
Current trends in educational assessment in different branches of higher education share the common goal of uniting learning with assessment. Most approaches and theoretical and practical developments in this field revolve around four main factors: feedback, democratization, alignment and relevance. This paper proposes the use of co-assessment as a means of ensuring dialogue-based, democratic and fairer evaluations. With co-assessment, the responsibility is shared by the teacher and the students, who negotiate and agree on the appraisal of student tasks and, in this paper, also on the awarded mark. The aim of this study is to analyse the relationship between a series of jointly agreed marks…
Effects of leflunomide on immune responses and models of inflammation.
1993
Leflunomide is an antiphlogistic and immunomodulating agent that has been shown to be effective in preventing and healing autoimmune disorders and reactions leading to organ graft rejection. From our preliminary clinical data [4], we now have hopes that these effects, observed in experimental animals, can truly be transferred to humans. Although we are far from understanding the mode of action of leflunomide, we are slowly gathering some insight. A good many of the immunosuppressive effects of leflunomide can be attributed to the antagonistic effects it has on responses to many cytokines, most likely through receptor expression and signal transduction (tyrosine kinase inhibition). The inhib…
Initial French language teacher education policy in Greece and curriculum evaluation among student teachers of FLE
2015
This paper presents initial language teacher education policy adopted in Greece and describes a study which examines student teachers’ of FLE (Français Langue Étrangère) perception of their initial teacher education and its contribution to their future professional life. The sample comprised 67 student teachers in their fourth year of studies for a bachelor degree in the department of French language and literature in the Aristotle University of Thessaloniki in Greece. Data were collected through questionnaires which included both a structured and an open-ended part. The questionnaire’s content was based on the European Profile for Language Teacher Education — a Frame of Reference (Kelly et…
Teststatistische Prüfung und Normierung der deutschen Versionen des EUROHIS-QOL Lebensqualität-Index und des WHO-5 Wohlbefindens-Index
2007
Zusammenfassung. Der Beitrag berichtet uber die teststatistische Prufung und Normierung der deutschen Versionen des EUROHIS-QOL 8 Item Index (EUROHIS-QOL) zur Erfassung der generischen Lebensqualitat und des Wohlbefindens-Index der WHO (WHO-5) zur Erfassung der Wohlbefindens aus Sicht der Befragten. Datengrundlage bildet eine reprasentative Stichprobe der bundesdeutschen Bevolkerung aus dem Jahr 2004. Die teststatistische Prufung verweist auf gute psychometrische Eigenschaften des EUROHIS-QOL Index. Obgleich Modifikationsmoglichkeiten bestehen, wird die Selektion von Items ausgeschlossen, weil dies den komzeptuellen Vorgaben der Indexkonstruktion widersprechen wurde. Die Ergebnisse der test…
Neue Perspektiven der laparoskopischen Simulation: Vom Studententrainingslabor bis zur Stressevaluation
2008
Hintergrund: Die Anwendung eines LapSim®-Trainingsmodells im Studententrainingslabor sowie die objektive Evaluation von Stress in einem virtuellen Operations-Szenario bieten neue Perspektiven der laparoskopischen Simulation. Methodik: Im Studententrainingslabor erfolgte bei 28 Probanden am LapSim® Virtual-Reality (VR)-Simulator in einem Trainingscurriculum, bestehend aus 9 Einheiten, die Erfassung von Lernkurven laparoskopischer Basisfertigkeiten sowie komplexer Prozesse. In einem virtuellen Operations-Szenario wurde des Weiteren bei 18 Chirurgen eine Stressevaluation mittels eines Sympathikografen vorgenommen und dabei die laparoskopische Fehler- und Komplikationsrate erfasst. Hierbei konn…
Birthing Support for Midwives and Mothers - ErgonomicTesting and Product Development
2012
Purpose: To further develop an ergonomic birthing support for increasing comfortable postures for midwives and mothers during deliveries. Methods and Results: First, the prototype of the birthing support and six birthing postures were tested with 8 midwives, 2 physicians, and 10 pregnant women in the last month of their pregnancy using visual analogue scales (VASs) and the System Usability Scale (SUS). According to the midwives and mothers, the best birthing postures were those with the mother sitting on the birthing support with the bed crosswise or the mother laying on her side on the bed with her leg on the birthing support. In the second stage of the study, 4 experts carried out an expe…
Psychometrische Güte der Selbst- und Fremdbeurteilungsinstrumente ADHS-SB und Wender-Reimherr-Interview bei Senioren mit Aufmerksamkeitsdefizit-/Hype…
2016
Zusammenfassung Ziel der Studie und Methodik Die Anwendbarkeit der etablierten ADHS-Verfahren für Erwachsene, ADHS-SB und Wender-Reimherr-Interview, im Senium wurde an einer Stichprobe von 324 Personen im Alter zwischen 60 und 99 Jahren überprüft. Ergebnisse Die beiden Verfahren weisen für den Einsatz bei SeniorInnen eine geringere psychometrische Güte auf im Vergleich zur Anwendung bei Erwachsenen im jungen und mittleren Lebensalter. Es zeigt sich eine hohe Korrelation beider Verfahren mit der klinischen Beurteilung der Experten bei Personen im Seniorenalter. Schlussfolgerung Als Ergänzung zur ausführlichen klinischen Exploration können die ADHS-SB und das WRI auch im Senium als valide Dia…