Search results for " evidence"

showing 10 items of 632 documents

Rationale and design of the DARWIN-T2D (DApagliflozin Real World evIdeNce in Type 2 Diabetes): A multicenter retrospective nationwide Italian study a…

2017

Background Randomized controlled trials (RCTs) in the field of diabetes have limitations inherent to the fact that design, setting, and patient characteristics may be poorly transferrable to clinical practice. Thus, evidence from studies using routinely accumulated clinical data are increasingly valued. Aims We herein describe rationale and design of the DARWIN-T2D (DApagliflozin Real World evIdeNce in Type 2 Diabetes), a multicenter retrospective nationwide study conducted at 50 specialist outpatient clinics in Italy and promoted by the Italian Diabetes Society. Data synthesis The primary objective of the study is to describe the baseline clinical characteristics (particularly HbA1c) of pa…

randomized controlled trial; real-life; retrospective study; sodium glucose co-transporter-2 inhibitor; medicine (miscellaneous); endocrinology; diabetes and metabolism; nutrition and dietetics; cardiology and cardiovascular medicineBlood GlucoseTime FactorsGlucosideGlycated Hemoglobin ATime FactorMedicine (miscellaneous)Settore MED/13 - EndocrinologiaEndocrinologyGlucosidesSodium-Glucose Transporter 2Retrospective StudieDiabetes MellitusHumansHypoglycemic AgentsData MiningBenzhydryl CompoundsRandomized controlled trial; Real-life; Retrospective study; Sodium glucose co-transporter-2 inhibitor; Benzhydryl Compounds; Biomarkers; Blood Glucose; Data Mining; Diabetes Mellitus Type 2; Glucosides; Glycated Hemoglobin A; Humans; Hypoglycemic Agents; Italy; Research Design; Retrospective Studies; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Time Factors; Treatment Outcome; Crowdsourcing; Evidence-Based Medicine; Medicine (miscellaneous); Endocrinology Diabetes and Metabolism; Nutrition and Dietetics; Cardiology and Cardiovascular MedicineSodium-Glucose Transporter 2 InhibitorsRetrospective StudiesGlycated HemoglobinBenzhydryl CompoundNutrition and DieteticsEvidence-Based MedicineHypoglycemic AgentSodium-Glucose Transporter 2 InhibitorRandomized controlled trial; Real-life; Retrospective study; Sodium glucose co-transporter-2 inhibitor; Benzhydryl Compounds; Biomarkers; Blood Glucose; Data Mining; Diabetes Mellitus Type 2; Glucosides; Glycated Hemoglobin A; Humans; Hypoglycemic Agents; Italy; Research Design; Retrospective Studies; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Time Factors; Treatment Outcome; Crowdsourcing; Evidence-Based MedicineReal-lifeBiomarkerDiabetes and MetabolismRandomized controlled trial; Real-life; Retrospective study; Sodium glucose co-transporter-2 inhibitor; Benzhydryl Compounds; Biomarkers; Blood Glucose; Data Mining; Diabetes Mellitus Type 2; Glucosides; Glycated Hemoglobin A; Humans; Hypoglycemic Agents; Italy; Research Design; Retrospective Studies; Sodium-Glucose Transporter 2; Time Factors; Treatment Outcome; Crowdsourcing; Evidence-Based Medicine; Medicine (miscellaneous); Endocrinology Diabetes and Metabolism; Nutrition and Dietetics; Cardiology and Cardiovascular MedicineRetrospective studyTreatment OutcomeDiabetes Mellitus Type 2ItalyRandomized controlled trialResearch DesignSodium glucose co-transporter-2 inhibitorCrowdsourcingCardiology and Cardiovascular MedicineBiomarkersType 2Human
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Professional mathematics teacher identity: analysis of reflective narratives from discourses and activities

2012

Published verson of an article in the journal: Journal of Mathematics Teacher Education. Also available from the publisher at: http://dx.doi.org/10.1007/s10857-012-9216-1 This article focuses on the methodological use of reflective narratives from discourses and activities of an experienced primary teacher as evidence of her professional identity. The teacher’s reflective narratives emerge from her participation in a 3-year developmental and research project, Learning Communities in Mathematics, conducted at the University of Agder (UiA) in Norway. As background for our study, we firstly present the teacher in action with her sixth-grade pupils in a mathematics lesson, and then analyse sele…

reflective narrativesocial theory of learningGeneral MathematicsLearning communityTeaching methodDiscourse analysisidentity indicatorIdentity (social science)professional mathematics teacher identityVDP::Mathematics and natural science: 400::Mathematics: 410Educationnarrative approachAction (philosophy)PedagogyMathematics educationNarrativePhilosophy of educationVDP::Social science: 200::Education: 280Empirical evidenceJournal of Mathematics Teacher Education
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Comparable efficacy and safety of dimethyl fumarate and teriflunomide treatment in Relapsing-Remitting Multiple Sclerosis: an Italian real-word multi…

2018

BACKGROUND: The aim of the study was to evaluate the achievement of 'no evidence of disease activity' (NEDA) over a 12-month period in a large multicenter population with relapsing remitting multiple sclerosis (RRMS) treated with delayed-release dimethyl fumarate (DMF) and teriflunomide (TRF) using a propensity-score adjustment. METHODS: A time-to-event method was used to determine the percentages of patients with RRMS (pwRRMS) in both groups achieving NEDA 3 (no relapses, no 12-week confirmed disability progression, and no new T2/gadolinium-enhancing brain lesions). We described the safety profile of the investigated drugs. RESULTS: Of the 587 pwRRMS treated with DMF and the 316 pwRRMS tre…

safetymedicine.medical_specialtydimethyl fumarate; efficacy; no evidence of disease activity 3; safety; teriflunomide; pharmacology; neurology; neurology (clinical)Populationefficacylcsh:RC346-429Disease activity03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicineTeriflunomideteriflunomideMedicine030212 general & internal medicineno evidence of disease activity 3educationlcsh:Neurology. Diseases of the nervous systemOriginal ResearchPharmacologyeducation.field_of_studydimethyl fumarateDimethyl fumaratebusiness.industryMultiple sclerosismedicine.diseasechemistryRelapsing remittingNeurologySettore MED/26 - NeurologiaReal wordNeurology (clinical)business030217 neurology & neurosurgerydimethyl fumarate; efficacy; no evidence of disease activity 3; safety; teriflunomide
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The Dynamic Relationship between Response Processes and Self-Regulation in Critical Thinking Assessments

2021

Our aim was to explore higher education students’ response and self-regulatory processes plus the relationship between these, as evidenced in two types of performance-based critical thinking tasks included in the Collegiate Learning Assessment (CLA+) International instrument. The data collection consisted of 20 cognitive laboratories. The data were analyzed using a qualitative approach. The tasks were found to trigger different response and self-regulatory processes. Overall, the performance task evoked more holistic processes than the selected-response questions, in which students’ processes were more question-oriented. The results also indicated the entanglement of students’ response and …

self-regulationhaasteet (ongelmat)Undergraduate studentsoppiminenHigher educationPERFORMANCE ASSESSMENTeducationLearning assessmentitsesääntelySTUDENTSResponse processesEducationTask (project management)0504 sociologyCOLLEGIATE LEARNING ASSESSMENTqualitative analysiscritical thinkingresponse processesitsearviointiData collectionopiskelijatbusiness.industry4. Education05 social sciencesVALIDITY EVIDENCE050401 social sciences methods050301 educationCognitionperformance-based assessmentPerformance-based assessmentCOMPETENCEundergraduate studentskriittinen ajattelukvalitatiivinen analyysiCritical thinkingkorkea-asteen koulutuskorkeakouluopiskeluSKILLSSelf-regulationUNIVERSITY516 Educational sciencesbusinessPsychologyarviointi0503 educationQualitative analysisCritical thinkingCognitive psychology
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Nuovi scenari nell'accesso transfrontaliero alla prova "elettronica"

2018

Il lavoro esamina le proposte presentate dalla Commissione europea in tema di prova elettronica, nonché le modifiche che si intendono apportare alla Convenzione di Budapest. L'ultima parte è dedicata alle possibili ricadute, sul versante europeo, del CLOUD Act.

service providerCLOUD ActSettore IUS/16 - Diritto Processuale PenaleCybercrime ConventionElectronic evidence
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Technical, tactical and spatial indicators related to goal scoring in European elite soccer

2020

The aim of this study was to describe the technical, tactical and spatial indicators related to goal scoring in elite European soccer, considering the type of defence and the positioning of the opponent. For the analysis, 8 tactical dimensions related to the final actions in 380 sequences that led to goal during the UEFA Champions League were evaluated by observational methodology. 75.9% of the goals were scored from open play and 24.1% were scored from set pieces. Collective actions produced 51.6% of the total goals while individual actions produced 10.5% of goals. Regarding the penultimate action, crosses were more frequent against organized defences, while passes in behind the defence, o…

sports performanceApplied psychologyscoring opportunitiesPhysical Therapy Sports Therapy and Rehabilitationmatch analysisLeague03 medical and health sciences0302 clinical medicineNotational analysisassociation footballEducación Física y Deportivalcsh:Sports medicineObservational methodologySports performance030229 sport sciencesAdversaryCircumstantial evidenceAssociation footballMatch analysisMatch analysisScoring opportunitiesEliteNotational analysisnotational analysisPsychologylcsh:RC1200-1245030217 neurology & neurosurgeryJournal of Human Sport and Exercise
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Replacing Project Managers in Information Technology Projects

2015

According to anecdotal evidence, project managers working on information technology (IT) projects are occasionally replaced, although the literature on information systems (IS) and project management (PM) makes little mention of it. With a view to narrowing this knowledge gap the authors examined the reasons behind the practice. The authors took an interpretive approach to the data gathering and analysis, and collected descriptions about replacing project managers (RPM) from interviews and questionnaires (n=43). The concept of contradiction served as a lens through which to identify the underlying reasons. Contradiction refers to statements asserting or expressing the opposite of another st…

ta113EngineeringKnowledge managementData collectionbusiness.industryIT project managementmedia_common.quotation_subjectContradictionsReplacementProject managerInformation technologyContext (language use)Public relationsTurnoverManagement of Technology and InnovationPhenomenonComputer Science (miscellaneous)Information systemContradictionProject managementbusinessta512Anecdotal evidencemedia_commonInternational Journal of Human Capital and Information Technology Professionals
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Internet Adoption at the User Level: Empirical Evidence from The Gambia

2014

The unified theory of acceptance and use of technology (UTAUT) are used to investigate technology adoption. However, its application in Sub-Saharan Africa is rare and barely extended to the validation phase. In this paper, we introduce six new moderating factors for UTAUT core determinants and two other direct determinants of Internet adoption. The objective of this approach is to identify relevant elements of Internet adoption at the user level in The Gambia. Moderating factors are interacting terms used when the relationship between independent and dependent variable is weak, inconsistent or non-existent. A case study research design was employed and the data were gathered in Autumn of 20…

ta113VariablesPublic Administrationbusiness.industrymedia_common.quotation_subjectDevelopmentUnified theory of acceptance and use of technologyComputer Science ApplicationsPyramidCase study researchThe InternetMarketingPsychologyEmpirical evidencebusinessmedia_commonInformation Technology for Development
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Changing people’s attitudes and beliefs toward driving through floodwaters : Evaluation of a video infographic

2018

Abstract Despite awareness of campaigns such as ‘Turn Around, Don’t Drown’ and the Australian state of Queensland’s ‘If It’s Flooded, Forget It’, people continue to drive through floodwaters, causing loss of life, risk to rescuers, and damage to vehicles. The aim of this study was to develop a video infographic that highlights the dangers of driving through floodwaters and provide safety tips to reduce the risk, and to evaluate its effectiveness in changing the beliefs and intentions of Australian adults toward this risky driving behaviour. This study adopted an online three-wave non-controlled pretest–posttest design. Australian licensed drivers (N = 201, male = 41, female = 160; Mage = 34…

ta520flooded waterwaysTransportationvesiäylät03 medical and health sciences0302 clinical medicineuskomuksethukkuminenPsychological TheorydrivingDrowning prevention030212 general & internal medicineta518Empirical evidenceApplied Psychologyta515Civil and Structural EngineeringSubjective norm030505 public healthwater safetyturvallisuusdrowningInfographicsocial cognitive theoriesRegretta3141tulvatwaterwaysRisk perceptionfloodsAutomotive Engineeringbeliefs0305 other medical sciencePsychologyLoss of lifeClinical psychologysafety and securityTransportation Research Part F : Traffic Psychology and Behaviour
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Family Firm Heterogeneity and Tax Aggressiveness: A Quasi-Experimental Analysis of the Impact of Different Family Generations

2021

This paper analyses tax aggressiveness in family firm generations. Moreover, taking into account the heterogeneity in family firms, we check whether the successive generations in control show different tax avoidance behaviour. The empirical evidence, based on the quasi-experiment of the 2012 Spanish thin capitalization rule, reveals that there is a positive relationship between tax aggressiveness and successive generations. Moreover, the founder and second generations follow a similar conservative tax avoidance approach, whereas the third and fourth generations are found to be more tax aggressive.

tax aggressivenessStrategy and ManagementControl (management)family firmthin capitalization ruleTax avoidancegenerationScopusPositive relationshipDemographic economicsBusinessleverageEmpirical evidenceCapitalizationJournal of Small Business Strategy
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