Search results for " expo"
showing 10 items of 1465 documents
Cardiovascular effects of impulse noise, road traffic noise, and intermittent pink noise at LAeq = 75 dB, as a function of sex, age, and level of anx…
1992
In a previous paper, in which the experimental conditions of the present research are fully described (Parrot et al., this issue), heart rate (HR) was studied in 60 male and in 60 female subjects in response to a pile-driver noise (P), a gunfire noise (G), a road traffic noise (T), and an intermittent pink noise (R), all noises being emitted at the same LAeq = 75 dB for 15 min. Digital pulse level (PL) responses were concomitantly surveyed by the use of pulse oximetry, allowing continuous arterial oxygen saturation (SaO2) readings. An index of pulse reactivity (PRI) could be calculated. Arterial blood pressure was measured 7 times from the beginning to the end of each trial. At rest, within…
Environmental exposure to dioxins and polychlorinated biphenyls reduce levels of gonadal hormones in newborns: Results from the Duisburg cohort study
2006
Abstract Background Endocrine dysfunction related to the hypothalamic–pituitary–thyroid (HPT) and/or the hypothalamic–pituitary–gonadal axis (HPG) is being discussed as underlying developmental adversity of polychlorinated dibenzo- p -dioxins and dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs). This study was done to evaluate effects related to the HPG axis. Methods A birth-cohort study was initiated in the year 2000. Healthy mother–infant pairs were recruited in the industrialized city of Duisburg, Germany. Dioxins, dioxin-like PCBs and six indicator PCBs were measured in maternal blood during pregnancy and in maternal milk. Testosterone and estradiol levels were measured in m…
Prenatal adversity: a risk factor in borderline personality disorder?
2012
BackgroundPatients with borderline personality disorder (BPD) show a high prevalence of early adversity, such as childhood trauma. It has also been reported that prenatal adverse conditions, such as prenatal maternal stress, drug taking, tobacco smoking or medical complications, may be associated with an increased risk of mental disorders in the offspring. Prenatal adversity is investigated here for the first time as a potential risk factor in the diagnosis of BPD.MethodA total of 100 patients with a DSM-IV diagnosis of BPD and 100 matched healthy controls underwent semi-structured interviews about the course of pregnancy, maternal stressors, birth complications and childhood trauma. Furthe…
Consensus meeting: monosodium glutamate – an update
2006
Update of the Hohenheim consensus on monosodium glutamate from 1997: Summary and evaluation of recent knowledge with respect to physiology and safety of monosodium glutamate.Experts from a range of relevant disciplines received and considered a series of questions related to aspects of the topic.University of Hohenheim, Stuttgart, Germany.The experts met and discussed the questions and arrived at a consensus.Total intake of glutamate from food in European countries is generally stable and ranged from 5 to 12 g/day (free: ca. 1 g, protein-bound: ca. 10 g, added as flavor: ca. 0.4 g). L-Glutamate (GLU) from all sources is mainly used as energy fuel in enterocytes. A maximum intake of 6.000 [c…
Maternal and paternal occupational exposure to agricultural work and the risk of anencephaly.
2006
Aims: To evaluate the association between parental occupational exposure to agricultural work and the risk of anencephaly in three Mexican states. Methods: A paired case control study (1:1) was done based on records of the Epidemiological Surveillance System of Neural Tube Defects in Mexico; 151 cases of anencephaly of more than 20 weeks’ gestation were selected between March 2000 and February 2001. Controls were selected from the same maternity services as those of the cases and were born alive without congenital malformations. Information was obtained from both parents by means of a general questionnaire, a food frequency questionnaire, and a specific questionnaire on occupational exposur…
Benefits of nonlinear analysis indices of walking stride interval in the evaluation of neurodegenerative diseases.
2021
Indices characterising the long-range temporal structure of walking stride interval (SI) variability such as Hurst exponent (H) and fractal dimension (D) may be used in addition to indices measuring the amount of variability like the coefficient of variation (CV). We assess the added value of the former indices in a clinical neurological context. Our aim is to demonstrate that they provide a clinical significance in aging and in frequent neurodegenerative diseases such as Parkinson's disease, Huntington, and amyotrophic lateral sclerosis. Indices assessing the temporal structure of variability are mainly dependent on SI time series length and algorithms used, making quantitative comparisons…
Are media warnings about the adverse health effects of modern life self-fulfilling? An experimental study on idiopathic environmental intolerance att…
2013
article i nfo Objective: Medically unsubstantiated 'intolerances' to foods, chemicals and environmental toxins are com- mon and are frequently discussed in the media. Idiopathic environmental intolerance attributed to electro- magnetic fields (IEI-EMF) is one such condition and is characterized by symptoms that are attributed to exposure to electromagnetic fields (EMF). In this experiment, we tested whether media reports promote the development of this condition. Methods: Participants (N=147) were randomly assigned to watch a television report about the adverse health effects of WiFi (n=76) or a control film (n=71). After watching their film, participants received a sham exposure to a WiFi …
Differences in hand and foot psychomotor speed among 18 pairs of monozygotic twins discordant for lifelong vehicular driving.
1997
The purpose of this study was to examine driving as a determinant of hand and foot psychomotor reaction times. Visual simple and choice hand and foot psychomotor reaction times were measured. The occupational driving contrast was determined by an interview reviewing every job held during each subject's lifetime. Comparison was made of psychomotor speed among 18 pairs of 39- to 62-year-old monozygotic male twins discordant for lifelong occupational driving. The mean discordance was the equivalent of 16 years of full-time driving. The twins who drove more tended to have slower hand simple and choice reaction times, although only the difference in hand-choice decision time was statistically si…
Prenatal mercury exposure and birth outcomes
2016
Background: Results regarding the association between mercury exposure and anthropometry at birth, gestational length and placental weight are inconsistent, as is the role of seafood intake in these asso- ciations. Objective: We assessed whether prenatal mercury exposure is associated with anthropometry at birth, placental weight and gestational length in a population with a relatively high exposure to mercury from seafood consumption. Methods: Total mercury (T – Hg) was determined in cord blood from 1869 newborns with birth outcome measures, within the Spanish multicenter INMA cohort from 2004 to 2008. We adjusted cohort speci fi c linear and Cox regression models to evaluate the associati…
Intraoperative C-arm CT imaging in angular stable plate osteosynthesis of distal radius fractures
2013
The purpose of this study was to analyze the practicability and benefit of intraoperative C-arm computed tomography (CT) imaging in volar plate osteosynthesis of unstable distal radius fractures. During a 1 year period, intraoperative three dimensional (3D) imaging with the ARCADIS Orbic 3D was performed in addition to standard fluoroscopy in 51 cases. The volar angular stable plate oesteosyntheses were analyzed intraoperatively and, if necessary, improved immediately. The duration of the scan and radiation exposure dose were measured. On average, performance of the scan and analysis of the CT dataset took 6.7 minutes. In 31.3% of the surgeries a misplacement of screws was detected and cor…