Search results for " fatty acid"

showing 10 items of 498 documents

Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis

2017

BackgroundDysbiosis has been recently demonstrated in patients with ankylosing spondylitis (AS) but its implications in the modulation of intestinal immune responses have never been studied. The aim of this study was to investigate the role of ileal bacteria in modulating local and systemic immune responses in AS.MethodsIleal biopsies were obtained from 50 HLA-B27+ patients with AS and 20 normal subjects. Silver stain was used to visualise bacteria. Ileal expression of tight and adherens junction proteins was investigated by TaqMan real-time (RT)-PCR and immunohistochemistry. Serum levels of lipopolysaccharide (LPS), LPS-binding protein (LPS-BP), intestinal fatty acid-BP (iFABP) and zonulin…

Genetics and Molecular Biology (all)Fatty Acid-Binding ProteinAnkylosing SpondylitisMonocyteBiochemistryMonocytesTransgenic0302 clinical medicineIntestinal MucosaMembrane GlycoproteinsZonulinCadherinsAdherens JunctionUp-RegulationAntigenAcute DiseaseMembrane GlycoproteinRats TransgenicInfectionHumanAnkylosingImmunologyGeneral Biochemistry Genetics and Molecular BiologyArticlePermeabilityTight Junctions03 medical and health sciencesRheumatologyAntigens CDIleumAnti-Bacterial AgentHuman Umbilical Vein Endothelial CellsHumansRNA MessengerEndotheliumProtein PrecursorsAnkylosing SpondylitiBiochemistry Genetics and Molecular Biology (all)BacteriaAnimalmedicine.diseaseDysbiosiSettore MED/16 - Reumatologia030104 developmental biologychemistryCase-Control StudiesImmunologyRatCarrier ProteinsAcute-Phase ProteinsSpondylitis0301 basic medicineLipopolysaccharidesLipopolysaccharideMessengerAcute-Phase ProteinGene Expressionchemistry.chemical_compoundIntestinal mucosaImmunology and AllergyMembrane ProteinHLA-B27 AntigenCaco-2 CellTight junctionTight JunctionAdherens JunctionsIleitisIleitiAnti-Bacterial AgentsCDmedicine.anatomical_structureAnkylosing Spondylitis; Infections; Inflammation; Acute Disease; Acute-Phase Proteins; Adherens Junctions; Animals; Anti-Bacterial Agents; Antigens CD; Bacteria; Caco-2 Cells; Cadherins; Carrier Proteins; Case-Control Studies; Cholera Toxin; Chronic Disease; Dysbiosis; Endothelium; Fatty Acid-Binding Proteins; Gene Expression; HLA-B27 Antigen; Human Umbilical Vein Endothelial Cells; Humans; Ileitis; Ileum; Interleukin-8; Intestinal Mucosa; Junctional Adhesion Molecule A; Lipopolysaccharides; Membrane Glycoproteins; Membrane Proteins; Monocytes; Permeability; RNA Messenger; Rats; Rats Transgenic; Spondylitis Ankylosing; Tight Junctions; Up-Regulationmedicine.symptomCase-Control StudieCholera ToxinHuman Umbilical Vein Endothelial CellLipopolysaccharideInflammationInfectionsFatty Acid-Binding ProteinsAdherens junctionmedicineAnkylosing Spondylitis; Infections; Inflammation; Acute Disease; Acute-Phase Proteins; Adherens Junctions; Animals; Anti-Bacterial Agents; Antigens CD; Bacteria; Caco-2 Cells; Cadherins; Carrier Proteins; Case-Control Studies; Cholera Toxin; Chronic Disease; Dysbiosis; Endothelium; Fatty Acid-Binding Proteins; Gene Expression; HLA-B27 Antigen; Human Umbilical Vein Endothelial Cells; Humans; Ileitis; Ileum; Interleukin-8; Intestinal Mucosa; Junctional Adhesion Molecule A; Lipopolysaccharides; Membrane Glycoproteins; Membrane Proteins; Monocytes; Permeability; RNA Messenger; Rats; Rats Transgenic; Spondylitis Ankylosing; Tight Junctions; Up-Regulation; Immunology and Allergy; Rheumatology; Immunology; Biochemistry Genetics and Molecular Biology (all)AnimalsSpondylitis AnkylosingAntigensSpondyliti030203 arthritis & rheumatologyInflammationHaptoglobinsbusiness.industryMonocyteInterleukin-8Membrane ProteinsRatsJunctional Adhesion Molecule AChronic DiseaseCadherinDysbiosisRNACaco-2 CellsCarrier ProteinbusinessDysbiosis
researchProduct

Strategies to Reduce Oxidative Stress in Glaucoma Patients

2018

Background Primary open-angle glaucoma (POAG) is a multifactorial pathology involving a variety of pathogenic mechanisms, including oxidative/nitrosative stress. This latter is the consequence of the imbalance between excessive formation and insufficient protection against reactive oxygen/nitrogen species. Objective Our main goal is to gather molecular information to better managing pathologic variants that may determine the individual susceptibility to oxidative/nitrosative stress (OS/NS) and POAG. Method An extensive search of the scientific literature was conducted using PUBMED, the Web of Science, the Cochrane Library, and other references on the topic of POAG and OS/NS from human and a…

Gingko bilobaIntraocular pressurePathologymedicine.medical_specialtygenetic structuresGlaucomaessential fatty acidsOxidative phosphorylationmedicine.disease_causeBioinformaticsArticlePathogenesisMelatonin03 medical and health scienceschemistry.chemical_compound0302 clinical medicinenatural compoundsAnimalsHumansMedicinePharmacology (medical)PharmacologyCoenzyme Q10business.industryGlaucomaGeneral Medicineoxidative stress.medicine.diseasenitrosative stresseye diseasesOxidative StressPsychiatry and Mental healthantioxidantsNeurologychemistry030221 ophthalmology & optometryNeurology (clinical)business030217 neurology & neurosurgeryOxidative stressmedicine.drugCurrent Neuropharmacology
researchProduct

Microwave-assisted catalytic esterification of α-glucoisosaccharino-1,4-lactone with tall oil fatty acids

2016

Background: Carbohydrates-rich materials are partly degraded during alkaline kraft pulping into a complex mixture of aliphatic carboxylic acids consisting of α-glucoisosaccharinic acid as one of the main acids. On the other hand, crude tall oil, containing significant amounts fatty acids, is obtained as a by-product from kraft pulping. One interesting novel approach is to utilize chemically both these side-streams by producing renewable surfactants from aliphatic carboxylic acids and fatty acids via esterification. Results: In this paper, lauric (C12:0) and oleic (C18:1) acids as well as a mixture of tall oil fatty acids were esterified with α-glucoisosaccharino-1,4-lactone in a microwave-a…

Glucoisosaccharinic acidchemistry.chemical_classificationLauric acidmicrowaveTall oilesterificationbatch reactorFatty acid02 engineering and technologytall oil fatty acids021001 nanoscience & nanotechnologyOleic acidLauric acidkraft pulpingCatalysischemistry.chemical_compoundOleic acid020401 chemical engineeringchemistryKraft processOrganic chemistry0204 chemical engineering0210 nano-technologyLactoneBlack liquorSustainable Chemical Processes
researchProduct

High-performance liquid chromatographic study of the regulation of phospholipid metabolism in cultured adrenocortical cells

1994

Abstract A rapid high-performance liquid chromatographic (HPLC) method for the separation of phospholipids was developed for minute samples of total lipids (ca. 200 μg). The method was applied to the study of the phospholipid metabolism in adrenocortical cell cultures. A complete separation of the different cellular phospholipid classes was achieved in 40 min. Good resolution of the phospholipid peaks was obtained, which allowed the collection of each individual class of phospholipids for further analysis of radioactivity and fatty acid composition by gas chromatography. When cells were incubated with [U-14C]glycerol or [U-14C]palmitate the bulk of the radioactivity was found in cellular ph…

GlycerolCardiolipinsPalmitatesPhospholipidHigh-performance liquid chromatographyMicechemistry.chemical_compoundTumor Cells CulturedGlycerolmedicineAnimalsCells CulturedChromatography High Pressure LiquidPhospholipidschemistry.chemical_classificationChromatographyAdrenal cortexPhosphatidylethanolaminesGeneral ChemistryMetabolismAdrenal Cortex NeoplasmsIn vitromedicine.anatomical_structurechemistryBiochemistryCell cultureAdrenal CortexPhosphatidylcholinesTetradecanoylphorbol AcetateIndicators and Reagentslipids (amino acids peptides and proteins)Polyunsaturated fatty acidJournal of Chromatography B: Biomedical Sciences and Applications
researchProduct

The metabolic versatility of PAOs as an opportunity to obtain a highly P-enriched stream for further P-recovery

2015

The effects of two sequencing batch reactor operation strategies for phosphorus stream enrichment over the biological phosphorus removal performance have been studied. The objective of both strategies is of performing an extraction cycle in order to obtain a new stream highly enriched with phosphorus. In the 1st strategy the amount of influent volatile fatty acids (VFAs) is the same in each cycle; while in the 2nd strategy the influent VFAs concentration is increased during phosphorus extraction experiments. Despite the strong decrease of the stored poly-P inside the cells in both strategies after the recovery cycles, the ability of the systems to remove phosphorus was not affected. The P-r…

Glycogen degradationGeneral Chemical EngineeringPhosphorusExtraction (chemistry)chemistry.chemical_elementSequencing batch reactorGeneral ChemistryPulp and paper industrySequencing batch reactor (SBR)Polyphosphate accumulating metabolism (PAM)Industrial and Manufacturing EngineeringVolatile fatty acidsEnhanced biological phosphorus removalchemistryBiochemistryPhosphorus recoveryPolyphosphate (poly-P)Carbon sourceEnhanced biological phosphorus removal (EBPR)Environmental ChemistryDegradation (geology)Glycogen accumulating metabolism (GAM)TECNOLOGIA DEL MEDIO AMBIENTE
researchProduct

Effects of diet on casein and fatty acid profiles of milk from goats differing in genotype for αS1-casein synthesis

2013

This study investigated the interactions between nutrition and the genotype at αS1-CN loci (CSN1S1) in goats, evaluating the impact of fresh forage-based diets and an energy supplement on the casein and fatty acid (FA) profiles of milk from Girgentana goats. Twelve goats were selected for having the same genotype at the αS2-CN, β- CN, and κ-CN loci and differing in the CSN1S1 genotype: homozygous for strong alleles (AA) or heterozygous for strong and weak alleles (AF). Goats of each genotype were divided into three groups and, according to a 3 × 3 Latin square design, fed ad libitum three diets: sulla fresh forage (SFF), SFF plus 800 g/day of barley (SFB), and mixed hay plus 800 g/day of ba…

Goat milkGoat milk; CSN1S1 genotype; Nutrition; Casein fraction; Milk fatty acidBiologyBiochemistryIndustrial and Manufacturing Engineeringchemistry.chemical_compoundCasein fractionLatin squareCaseinGenotypeSettore AGR/18 - Nutrizione E Alimentazione AnimaleDry matterFood scienceNutritionMilk fatty acidchemistry.chemical_classificationRumenic acidfood and beveragesFatty acidGeneral ChemistryOleic acidchemistryCSN1S1 genotypeHayFood ScienceBiotechnologyEuropean Food Research and Technology
researchProduct

Effects of Grazing Season on Physico-Chemical Characteristics and Fatty Acids of Nutritional Interest of Caciocavallo Palermitano Cheese

2022

The aim of this work was to evaluate, in the different production seasons of the year, the physico-chemical quality of an artisanal cheese traditionally obtained from autochthonous grazing cows, with particular reference to fatty acids (FA) of nutritional interest that play an important role in the risk or prevention of some human pathologies. For this purpose, cheeses were sampled in 11 farms, repeating the samplings in 3 different periods of the year (summer, autumn–winter, and spring) when the productive conditions of the pastures varied. The cheeses produced in the spring period, when cows ingest a greater amount of grazed forage, resulted in a more adequate composition of the main FA, …

GrazingSettore AGR/19 - Zootecnica SpecialeGeneral Veterinarygrazing; autochthonous cow breeds; artisanal cheese; fatty acids; nutritional indices; human healthHuman healthAnimal Science and ZoologyArtisanal cheeseNutritional indicesAutochthonous cow breedFatty acid
researchProduct

Lentil Fortified Spaghetti: Technological Properties and Nutritional Characterization

2021

Lentil (Lens culinaris), consumed as a part of the diet worldwide, is a functional dietary ingredient that plays a function in human nutrition as a rich source of bioactive nutrients (low quantities of fat, sodium, and vitamin K

Health (social science)Absorption of waterSettore CHIM/10 - Chimica Degli AlimentiPotassiumSodiumchemistry.chemical_elementPlant Scienceessential fatty acidsdurum wheat spaghettilcsh:Chemical technologyHealth Professions (miscellaneous)MicrobiologyArticlelentilNutrientmedicinelcsh:TP1-1185Food sciencefortified pastachemistry.chemical_classificationcarboxymethyl cellulosefood and beveragesessential amino acidsCarboxymethyl celluloseHuman nutritionchemistryPolyphenolcmcFood SciencePolyunsaturated fatty acidmedicine.drugFoods
researchProduct

Improvement of Fatty Acid Profile in Durum Wheat Breads Supplemented with Portulaca oleracea L. Quality Traits of Purslane-Fortified Bread

2020

The addition of functional ingredients to breads could have effects on preventing cardiovascular diseases, cancers and inflammation. The incorporation of 0&ndash

Health (social science)Antioxidant<i>Portulaca oleracea</i> L.Settore CHIM/10 - Chimica Degli Alimenti030309 nutrition & dieteticsmedicine.medical_treatmentWheat flouressential fatty acidsPlant ScienceNutritional qualityPortulacaAntioxidant potentialdurum wheat breadlcsh:Chemical technologyHealth Professions (miscellaneous)Microbiology03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologydurum wheat bread; Portulaca oleracea L.; essential fatty acids; omega-6/omega-3 ratio; antioxidantsmedicineessential fatty acidlcsh:TP1-1185Food sciencePhenolschemistry.chemical_classification0303 health sciencesABTSPortulaca oleracea L.biologydigestive oral and skin physiologyfood and beveragesFatty acid04 agricultural and veterinary sciencesbiology.organism_classification040401 food scienceantioxidantschemistryomega-6/omega-3 ratioFood Science
researchProduct

Land Snails as a Valuable Source of Fatty Acids: A Multivariate Statistical Approach

2019

The fatty acid (FA) profile of wild Theba pisana, Cornu aspersum, and Eobania vermiculata land snail samples, collected in Sicily (Southern Italy), before and after heat treatment at +100 °C were examined by gas chromatography with a flame ionization detector (GC-FID). The results show a higher content of polyunsaturated fatty acids (PUFAs) in all of the examined raw snails samples, representing up to 48.10% of the total fatty acids contents, followed by monounsaturated fatty acids (MUFAs). The thermal processing of the snail samples examined determined an overall reduction of PUFA levels (8.13%, 7.75%, and 4.62% for T. pisana, C. aspersum and E. vermiculata samples, respectively) and a spe…

Health (social science)principal component analysis030309 nutrition & dieteticsTheba pisanaPlant Sciencefatty acidsHealth Professions (miscellaneous)MicrobiologyArticle03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologyland snailsfatty acids; land snails; GC‐FID; heat processing; principal component analysisparasitic diseasesFood sciencechemistry.chemical_classification0303 health sciencesheat processingbiologyChemistryland snailLand snailFatty acidFatty acids GC-FID Heat processing Land snails Principal component analysis04 agricultural and veterinary sciencesbiology.organism_classification040401 food scienceOleic acidSaturated fatty acidfatty acidGC-FIDCornu aspersumEobania vermiculataFood SciencePolyunsaturated fatty acidfatty acids; land snails; GC-FID; heat processing; principal component analysisFoods; Volume 8; Issue 12; Pages: 676
researchProduct