Search results for " fever"

showing 10 items of 173 documents

Interleukin-12 in Human Boutonneuse Fever Caused by Rickettsia conorii

2000

Interleukin (IL)-12 contributes to the resistance against a number of intracellular pathogens. We examined the potential biological role of IL-12 by studying peripheral blood mononuclear cells (PBMC), its production and its effect on cytokine synthesis in 20 Sicilian patients with boutonneuse fever (BF) caused by Rickettsia conorii. Data indicate that PBMC from acute BF patients were able to produce IL-12 in response to in vitro stimulation with rickettsial antigen (Ag): this production was higher than that detected in healed patients. Monocytes were the main source of IL-12 by PBMC from BF patients. IL-12 secretion by in vitro Ag-stimulated PBMC from BF patients was potentiated by recombin…

medicine.drug_classImmunologyInterleukinGeneral MedicineRecombinant Interferon GammaBiologyBoutonneuse Fevermedicine.diseaseMonoclonal antibodybiology.organism_classificationInterleukin-12Peripheral blood mononuclear cellInterleukin-10Boutonneuse feverInterferon-gammaRickettsia conoriiImmunityImmunologyLeukocytes MononuclearmedicineInterleukin 12HumansInterleukin-4Rickettsia conoriiScandinavian Journal of Immunology
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Prevalence of ulcerative stomatitis in arbovirus infections in a Brazilian Northeast population

2020

Background Although there are no population-based studies that support an association, there are reports in the literature of mucocutaneous, vesiculobullous and ulcerated lesions in the oral mucosa in cases of arbovirus infection. The aim of this study is to analyze the prevalence of ulcerative stomatitis in individuals affected by arboviruses in a population of the municipality of Arcoverde, Pernambuco, Brazil. Material and Methods 1,003 people living in an area assigned to a Primary Health Care Unit were interviewed. A structured questionnaire was used for data collection, with questions about sociodemographic variables, residence conditions, general health information, as well as informa…

medicine.medical_specialtyArbovirus InfectionsArbovirus infectionsvirusesMucocutaneous zonePopulationArbovirus Infectionsmedicine.disease_causeArbovirusDengue feverZika virusDengue03 medical and health sciences0302 clinical medicineUlcerative StomatitismedicinePrevalenceHumansChikungunyaOral mucosaeducationGeneral DentistryChikungunya fevereducation.field_of_studyOral Medicine and Pathologybusiness.industryResearchvirus diseases030206 dentistrybiochemical phenomena metabolism and nutrition:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseDermatologymedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASChikungunya FeverSurgerybusinessArbovirusesBrazil
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The History of Rheumatic Diseases

1975

The lectures of Schonlein* (1873) (Fig. 1) state: The nature of this disease being more dynamic, explains the fact that few abnormalities of significance have been found at autopsy. This statement stems from the inadequacy of the then current methods but also suggests a concept of rheumatic diseases, some ingredients of which have survived to this day. However, even a short review of medical history shows progressive differentiation of various disease entities: originally Hippocrates (460–377 BC) took “Rheuma” and “Catarrh” to be synonymous with a process during which “mucous flux” left the brain for various foci in the entrails and also the joints, and there produced disease. He mentions “…

medicine.medical_specialtyCollagen diseasebusiness.industryCatarrhRheumatic diseaseAutopsyDiseasemedicine.diseaseDermatologymedicineRheumatic feverMedical historybusinessRheumatism
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Is respiratory protection appropriate in the Ebola response?

2014

medicine.medical_specialtyInfectious Disease Transmission Patient-to-ProfessionalText miningProtective Clothingbusiness.industrymedicineHumansGeneral MedicineHemorrhagic Fever EbolaRespiratory systemIntensive care medicinebusinessThe Lancet
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Fokussuche bei neutro- penischem Fieber

2000

medicine.medical_specialtyLeukopeniamedicine.diagnostic_testbusiness.industryNeutropenic feverInterventional radiologyNeutropeniamedicine.diseaseEtiologyMedicineRadiology Nuclear Medicine and imagingRadiologymedicine.symptombusinessCardiac imagingNeuroradiologyDer Radiologe
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Juvenile Rheumatoid Arthritis and Still’s Disease

1975

In the Anglo-American literature, the term “Still’s disease”, based on the observations of ○Cornil (1864) and Still (1897) is generally employed to cover the juvenile forms of rheumatoid arthritis, defined by Ansell and Bywaters (1959). German paediatricians, on the other hand, particularly Storber and Kolle, regard Still’s disease as a separate syndrome. Kolle uses the following characteristics for this distinction: 1. High fever at the commencement of illness. 2. Enlargement of lymph nodes, spleen and liver. 3. Myocarditis and pericarditis. 4. High leucocyte count. 5. Erythema multiforme in about 70% of patients.

medicine.medical_specialtyMyocarditisbusiness.industryInterstitial nephritisDiseasemedicine.diseaseDermatologyPericarditisRheumatoid arthritismedicineRheumatic feverErythema multiformebusinessJuvenile rheumatoid arthritis
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Turpentine-induced fever during stimulation and inhibition of hepatic protein synthesis

2003

Abstract 1. Male Wistar rats pretreated with d -galactosamine (500 mg/kg, i.p.), a specific inhibitor of hepatic protein synthesis, developed attenuated and prolonged fever in response to turpentine (0.5 ml/rat, s.c.). 2. Hepatic protein synthesis stimulator epinephrine (1.8 mg/kg, s.c.) did not affect body temperature response of Wistar rats to turpentine. 3. Both d -galactosamine (500 mg/kg) and epinephrine (1.8 mg/kg) failed to affect body temperature in non-febrile rats. 4. These data support the hypothesis that liver-synthesised acute phase proteins might be involved in mechanisms of fever, probably, as modulators of activated cytokine network, mediating febrile response.

medicine.medical_specialtyPhysiologybusiness.industryProlonged feverAcute-phase proteinTurpentineStimulationBiochemistrychemistry.chemical_compoundEpinephrineEndocrinologychemistryInternal medicineGalactosaminemedicineGeneral Agricultural and Biological SciencesbusinessHEPATIC PROTEINTemperature responseDevelopmental Biologymedicine.drugJournal of Thermal Biology
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AB0715 THE PREVALENCE OF FIBROMIYALGIA IN PATIENTS WITH FAMILIAL MEDITERRANEAN FEVER AND THE RELATIONSHIP BETWEEN FATIGUE AND QUALITY OF LIFE

2021

Background:Familial Mediterranean Fever (FMF) can cause various muscle diseases. Because it is a chronic auto inflammatory disease, painful trigger points may be encountered in the examination due to a decrease in the pain threshold (1-3).Objectives:The aim of this study was to determine the prevalence of Fibromiyalgia in patients with FMF, at the same time to identify the relationship between fatigue and quality of life.Methods:Sixtyseven patients (38 female, 29 male) with FMF were enrolled in the study. They were diagnosed with FMF based on the Livneh diagnostic criteria (4). Fibromyalgia involvement of the patients was evaluated according to the Fibromyalgia Impact Questionnaire (FIQ). P…

medicine.medical_specialtybusiness.industryImmunologyFamilial Mediterranean fevermedicine.diseaseGeneral Biochemistry Genetics and Molecular BiologyRheumatologyRheumatologyQuality of lifeFibromyalgiaInternal medicineThreshold of painImmunology and AllergyMedicineFamily historybusinessBody mass indexDepression (differential diagnoses)Annals of the Rheumatic Diseases
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Subclinical Infections with Boutonneuse Fever in Western Sicily

1985

medicine.medical_specialtybusiness.industryRickettsiaceae InfectionsBoutonneuse Fevermedicine.diseaseDermatologyBoutonneuse feverInfectious DiseasesHumansImmunology and AllergyMedicinebusinessSicilySubclinical infectionJournal of Infectious Diseases
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Early Treatment of Systemic Juvenile Idiopathic Arthritis with Canakinumab and Complete Remission After 2 Years of Treatment Suspension: Case Report …

2019

Systemic juvenile idiopathic arthritis (sJIA) is an autoinflammatory disease characterised by fever and arthritis. We describe the case of a 14-year-old girl hospitalised with fever associated with rash, myalgia, arthralgia and polyarticular involvement. Examinations revealed increased levels of C-reactive protein, erythrocyte sedimentation rate, ferritin, triglycerides, leukocytes, neutrophils, lactate dehydrogenase, fibrinogen, aspartate aminotransferase (AST), alanine aminotransferase (ALT) and γ-glutamyl transferase (GGT). Bone marrow biopsy showed polyclonal leukocyte activation. A genetic study revealed a heterozygous mutation of the MEFV gene, c.442G>C (E148Q), which is typical of…

myalgiaAbdominal painmedicine.medical_specialtyTime FactorsAdolescentCanakinumabFamilial Mediterranean feverArthritisCase Report030204 cardiovascular system & hematologyAntibodies Monoclonal Humanized030226 pharmacology & pharmacyGastroenterology03 medical and health sciences0302 clinical medicineautoinflammatory diseaseInternal medicinemedicineHumansPharmacology (medical)medicine.diagnostic_testbusiness.industryRemission InductionAntibodies MonoclonalGeneral MedicineExanthemamedicine.diseaseMEFVRashdigestive system diseasesArthritis JuvenileCanakinumabTreatment OutcomeErythrocyte sedimentation rateSystemic juvenile idiopathic arthritiFemalemedicine.symptombusinessmedicine.drug
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