Search results for " flaps"

showing 10 items of 187 documents

Non-viral VEGF(165) gene therapy--magnetofection of acoustically active magnetic lipospheres ('magnetobubbles') increases tissue survival in an overs…

2008

Abstract Adenoviral transduction of the VEGF gene in an oversized skin flap increases flap survival and perfusion. In this study, we investigated the potential of magnetofection of magnetic lipospheres containing VEGF165-cDNA on survival and perfusion of ischemic skin flaps and evaluated the method with respect to the significance of applied magnetic field and ultrasound. We prepared perfluoropropane-filled magnetic lipospheres (‘magnetobubbles’) from Tween60-coated magnetic nanoparticles, Metafectene, soybean-oil and cDNA and studied the effect in an oversized random-pattern-flap model in the rats (n= 46). VEGF-cDNA-magnetobubbles were administered under a magnetic field with simultaneousl…

MalePathologymedicine.medical_specialtyNecrosismagneticAngiogenesisGenetic enhancementDermatologic Surgical ProceduresEnzyme-Linked Immunosorbent AssayTransfectionSurgical FlapsRats Sprague-DawleyMagneticsangiogenesismagnetobubblesmedicineAnimalsUltrasonicsSkinbusiness.industryVascular Endothelial Growth FactorsMusclesUltrasoundGraft SurvivalCell BiologyTransfectionGenetic TherapySkin TransplantationArticlesequipment and suppliesLipidsVEGFgene therapyMicrospheresRatsMicrovesselsModels AnimalMagnetofectionMolecular MedicineMagnetic nanoparticleslipospheresmedicine.symptombusinessPerfusionhuman activitiesmagnetofectionJournal of cellular and molecular medicine
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Incidence and types of complications after ablative oral cancer surgery with primary microvascular free flap reconstruction.

2015

Background: The aims of the study were 1) to evaluate the incidence and types of postoperative complications after ablative oral cancer surgery with primary free flap reconstruction and 2) identify prognostic variables for postoperative complications. Material and Methods: Desired data was retrieved from a computer database at the department of Oral and Maxillofacial Department, Queen Elisabeth hospital Birmingham, United Kingdom, between June 2007 and October 2012. Logistic regression was used to study relationships between preoperative variables and postoperative outcomes. Results: The study population consisted 184 patients, comprising 189 composite resections with reconstruction. Compli…

MalePrognostic variablemedicine.medical_specialtyOdontologíaFree flapLogistic regressionFree Tissue FlapsPostoperative ComplicationsSDG 3 - Good Health and Well-beingAblative caseMedicineHumansGeneral DentistryRetrospective StudiesMouth neoplasmbusiness.industryIncidence (epidemiology)IncidenceResearchRetrospective cohort studyLength of StayMiddle Aged:CIENCIAS MÉDICAS [UNESCO]PrognosisCiencias de la saludSurgeryOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASMicrovessels/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingPopulation studySurgeryFemaleMouth NeoplasmsOral SurgerybusinessMedicina oral, patologia oral y cirugia bucal
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The face lift SMAS plication flap for reconstruction of large temporofrontal defects: reconstructive surgery meets cosmetic surgery.

2011

Background: Reconstruction of large defects in the temporal region can be performed with skin grafts or pedicled or free flaps. Results are often not optimal because of the patch of a skin graft, lack of availability of local flaps, and distant skin from free flaps. A technique for reconstruction of these defects with local tissue is presented in this article that uses superficial musculoaponeurotic system (SMAS) plication to allow wide advancement of a cervicofacial flap. Methods: Once the defect is outlined, a face-lift–like skin incision is used to raise the flap. The SMAS is plicated with two purse-string sutures that relieve tension on the flap and allow maximal advancement. Thirteen f…

MaleReconstructive surgerymedicine.medical_specialtyCervicofacial flapTreatment outcomeSettore MED/19 - Chirurgia PlasticaCosmetic TechniquesSurgical FlapsmedicineHumansSurgical FlapsAgedRetrospective StudiesAged 80 and overintegumentary systemPlicaturabiologyface liftbusiness.industrycosmetic surgeryFollow up studiesSkin TransplantationMiddle Agedbiology.organism_classificationreconstructive surgeryeye diseasesSurgeryCosmetic TechniquesFace surgeryTreatment OutcomeFaceRhytidoplastySurgeryFemalesmaFacial NeoplasmsbusinessFollow-Up StudiesPlastic and reconstructive surgery
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XEN-augmented Baerveldt Implantation for Refractory Childhood Glaucoma: A Retrospective Case Series

2019

Background Tube implants can lead to long-term decompensation of the cornea after decades, in particular in complicated childhood glaucoma, because of a variety of causes including contact between the tube tip and the corneal endothelium. The augmentation of a XEN implant with a Baerveldt (250) tube implant, introduced 2016 by Mermoud et al for refractory glaucoma in adult patients, may reduce this risk in children. In our retrospective study, we report on the XEN-augmented Baerveldt (250) tube implant in children. Patients and methods Ten consecutive patients with refractory childhood glaucoma who underwent XEN-augmented Baerveldt implantation by a single surgeon (F.G.) between January 201…

MaleReoperationmedicine.medical_specialtyIntraocular pressureCorneal endotheliumAdolescentgenetic structuresGlaucomaSurgical FlapsProsthesis ImplantationTonometry Ocular03 medical and health sciencesPostoperative Complications0302 clinical medicineCorneaHumansMedicineDecompensationChildGlaucoma Drainage ImplantsIntraoperative ComplicationsIntraocular PressureRetrospective StudiesSlit lampbusiness.industryHydrophthalmosInfantmedicine.diseaseeye diseasesSurgeryPosterior segment of eyeballOphthalmologyTreatment Outcomemedicine.anatomical_structureChild Preschool030221 ophthalmology & optometryFemalesense organsImplantbusinessSclera030217 neurology & neurosurgeryJournal of Glaucoma
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Freestyle-Like V-Y Flaps of the Eyebrow: A New Outlook and Indication of an Historical Technique

2013

The eyebrow region is of utmost importance for facial movement, symmetry, and the overall cosmetic appearance of the face. Trauma or tumor resection often leave scars that may dislocate the eyebrow producing an alteration both in static symmetry of the face and in the dynamic expressivity. The authors present a technique for eyebrow’s defects repair using the remaining eyebrow advancement by means of a “freestyle-like” V-Y flap. In the past two years a total of eight consecutive patients underwent excision of skin lesions in the superciliary region and immediate reconstruction with this technique. On histology, six patients were affected from basal cell carcinomas, one from squamous cell ca…

MaleSkin NeoplasmsReconstructive Surgical Procedures/methodsEyebrowSettore MED/19 - Chirurgia Plasticalcsh:MedicineScarsOphthalmologic Surgical Procedureslcsh:TechnologySurgical Flapslcsh:ScienceSkin Neoplasms/surgeryNevus Intradermal/surgeryGeneral Environmental ScienceAged 80 and overV-Y flap eyebrow defectGeneral MedicineMiddle AgedCarcinoma Basal Cell/surgerymedicine.anatomical_structureTreatment OutcomeNevus Intradermalmedicine.symptomAdultCosmetic appearancemedicine.medical_specialtyArticle SubjectTumor resectionFree Tissue FlapsGeneral Biochemistry Genetics and Molecular BiologymedicineHumansNeoplasms Squamous Cell/surgeryBasal cellNeoplasms Squamous CellFacial movementSurgical FlapsAgedlcsh:Tbusiness.industrylcsh:ROphthalmologic Surgical Procedures/methodsPlastic Surgery ProceduresSurgeryEyebrow regionCarcinoma Basal CellClinical Studylcsh:QEyebrowsbusiness
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Cranioplasty with autologous bone flaps cryopreserved with Dimethylsulphoxide : does tissue processing matter

2021

Este artículo se encuentra disponible en la siguiente URL: https://www.sciencedirect.com/science/article/abs/pii/S1878875021001625?via%3Dihub En este artículo de investigación también participan: Dolores Ocete, Lucas Aranda, Ana Melero, Antonio J. Guillot, Nuria Yagüe y Carlos Botella. Este es el pre-print del siguiente artículo: Mirabet, V., García, D., Roca, A., Quiroz, A. R., Antón, J., Rodríguez-Cadarso, M., Ocete, D., Aranda, L., Melero, A., Guillot, A. J., Yagüe, N., Guillén, I. & Botella, C. (2021). Cranioplasty with autologous bone flaps cryopreserved with Dimethylsulphoxide: does tissue processing matter. World Neurosurgery, vol. 149 (may.), pp. e582?e591, que se ha publicado de fo…

MaleTime Factorsmedicine.medical_treatmentBrain EdemaSurgical Flaps0302 clinical medicineCryoprotective AgentsPostoperative ComplicationsHuesos - Crioconservación.Brain Injuries TraumaticAutograftsAutologous bone flapMiddle AgedCranioplastyResorptionAnti-Bacterial AgentsStrokeCryopreservacion of organs tissues etc.030220 oncology & carcinogenesisTissue bankVancomycinDecompressive craniectomyFemalemedicine.drugCrioconservación de órganos tejidos etc.Adultmedicine.medical_specialtyDecompressive CraniectomyAdolescentDecompressive craniectomyCráneo - Cirugía.CranioplastySkull - Surgery.03 medical and health sciencesYoung AdultmedicineHumansSurgical Wound InfectionDimethyl SulfoxideBones - Cryopreservacion.Bone ResorptionCryopreservationbusiness.industryBone storageSkullPostoperative complicationBone processingPlastic Surgery Proceduresmedicine.diseaseSurgeryHydrocephalusSurgeryNeurology (clinical)businessComplication030217 neurology & neurosurgery
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Advancement Perforator Cheek Flap for Aesthetic One-Stage Reconstruction of Postoncological Extended Split-Thickness Defects of the Nasal Sidewall

2013

Aesthetic reconstruction of soft tissue nasal sidewall loss has an important influence on the appearance of the nose. The unique character of this subunit and the complex relationships with a number of different facial or nasal subunits make the excision of large tumors difficult to manage. Numerous techniques are described in the literature, but a primary reconstruction with a final good result is not often possible. The authors develop an advancement cheek flap for an aesthetic one-stage reconstruction of postoncological extended nasal sidewall defects. Between January 2009 and July 2012, 16 patients (mean age, 63.3 yr) underwent excision of skin tumors of nasal sidewall and immediate rec…

Malemedicine.medical_specialtyArticle Subjectmedicine.medical_treatmentNose NeoplasmsSettore MED/19 - Chirurgia Plasticalcsh:Medicinelcsh:TechnologyNose neoplasmSurgical FlapsGeneral Biochemistry Genetics and Molecular BiologyCheek flapRhinoplastymedicine.arterymedicineHumansSurgical Flapslcsh:ScienceNoseAgedGeneral Environmental Sciencelcsh:Tbusiness.industryCarcinomalcsh:RNose Deformities AcquiredSoft tissueSkin TransplantationGeneral MedicineAnatomyMiddle AgedCheekRhinoplastySuperficial temporal arterySurgeryCheekmedicine.anatomical_structureClinical StudyFemalelcsh:QAdvancement Perforator Cheek Flap Extended Split-Thickness Defects Nasal Sidewall reconstructionbusiness
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Surgical treatment of pharyngostomes in irradiated patients. Our experience with musculocutaneous pectoralis major flap and hyperbaric oxygen therapy

2005

Surgical treatment of pharyngostomes in irradiated patients. Our experience with musculocutaneous pectoralis major flap and hyperbaric oxygen therapy. Cordova A, Corradino B, Pirrello R, Di Lorenzo S, Dispenza C, Moschella F. Source Dipratimento di Discipline Chirurgiche ed Oncologiche, Divisione di Chirurgia Plastica e Ricostruttiva, Facolta di Medicina, Universita di Palermo, Palermo, Italy. chirplas@unipa.it Abstract CONCLUSION: Our experience confirms that pectoralis major flap is the first-choice technique for repairing recurrent hypopharyngeal fistulae in previously irradiated patients in whom microsurgical techniques are not indicated, and that hyperbaric oxygen therapy helps to solv…

Malemedicine.medical_specialtyCutaneous FistulaFistulamedicine.medical_treatmentLaryngectomyHyperbaric oxygen therapy hypopharyngeal fistula pectoralis major flap pharyngolaryngeal carcinoma pharyngolaryngeal reconstruction pharyngostomeSurgical FlapsPectoralis MusclesPostoperative ComplicationsCarcinomamedicineHumansSurgical FlapsPectoralis MuscleLaryngeal NeoplasmsAgedAged 80 and overHyperbaric Oxygenationbusiness.industryPectoralis major musclePharyngeal NeoplasmsPharyngeal DiseasesGeneral MedicineMiddle AgedPlastic Surgery Proceduresmedicine.diseaseSurgeryLaryngectomyTreatment OutcomePharyngeal NeoplasmOtorhinolaryngologyFemaleRadiotherapy AdjuvantComplicationbusiness
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Fistulectomy and sphincteric reconstruction for complex cryptoglandular fistulas

2009

Objective  Complex anal fistulas (CFs) are difficult to treat. Endoanal advancement flap (EAF) is one of the standard treatment options for such clinical conditions. Immediate sphincter repair after fistulectomy (ISR) is not commonly performed because of the fear of causing postoperative incontinence. The objective of this study was to compare the results of both techniques. Method  We retrospectively analysed a prospectively entered database composed of 146 patients (112 M; 34 F), undergoing operations for CF of cryptoglandular origin. The patients were divided in two groups: Group A: (EAF); n = 71 patients; Group B: (ISR); n = 75 patients. Results  Forty-two fistulas (28.7%) were recurren…

Malemedicine.medical_specialtyFistulaFistulectomyAnal CanalGroup ASurgical FlapsGroup BQuality of lifeRisk FactorsSecondary PreventionmedicineHumansRectal FistulaRetrospective Studiesbusiness.industryStandard treatmentGastroenterologyRetrospective cohort studyColonoscopyMiddle AgedPlastic Surgery Proceduresmedicine.diseaseSurgeryTreatment Outcomemedicine.anatomical_structureQuality of LifeSphincterFemalebusinessFecal IncontinenceColorectal Disease
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Post laryngectomy speech rehabilitation outcome in elderly patients

2013

The aim of our work has been to evaluate the different options of tracheoesophageal voice rehabilitation in over 70-year-old patients, who had undergone laryngectomy, assessing advantages and drawbacks of this method of vocal recovery. A retrospective study has been carried out. This has included 40 subjects, all aged more than 70 years old, who have been referred to tracheoesophageal voice rehabilitation. It has been realized a phonatory fistula between trachea and esophagus with prosthesis positioning by means of a primary puncture in 18 cases and it has been realized a secondary puncture in 22 cases. The results gathered in these patients were compared with data obtained from a group mad…

Malemedicine.medical_specialtyFistulamedicine.medical_treatmentPunctureslaryngectomy; aged; laryngeal prosthesisSpeech TherapyProsthesisSurgical FlapsAlaryngeal speechPostoperative ComplicationsLaryngectomy Alaryngeal speech Laryngeal prosthesis Aged OutcomemedicineHumanslaryngeal prosthesislaryngectomyRetrospective StudiesAged 80 and overRehabilitationbusiness.industryRetrospective cohort studyGeneral Medicinemedicine.diseaseSurgeryLaryngectomySpeech AlaryngealagedTreatment OutcomeOtorhinolaryngologyOtorhinolaryngologyCase-Control StudiesFemalebusinessLarynx ArtificialTracheoesophageal Puncture
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