Search results for " function"

showing 10 items of 9395 documents

Nierenfunktionspr�fung bei Ratten durch den Phenolsulfonphthalein-Test

1963

Ein Verfahren zur Durchfuhrung des Phenolsulfonphthalein-Testes an Ratten wird beschrieben. Die Tiere erhalten 5 mg Phenolsulfonphthalein/kg Korpergewicht als i.v. Injektion. 1 min und 10 min nach der Farbstoffgabe werden die Farbstoffkonzentrationen im Serum gemessen. Die Farbstoffretention nach 10 min ausgedruckt in Prozenten des 1 min-Wertes wird als Mas der Nierenfunktionsleistung angesehen.

Andrologybusiness.industryDrug DiscoveryMolecular MedicineMedicineRenal functionGeneral MedicinebusinessGenetics (clinical)Klinische Wochenschrift
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Endothelial Leptin Receptor Deletion Promotes Cardiac Autophagy and Angiogenesis Following Pressure Overload by Suppressing Akt/mTOR Signaling.

2019

Background: Cardiac remodeling is modulated by overnutrition or starvation. The adipokine leptin mediates energy balance between adipose tissue and brain. Leptin and its receptors are expressed in the heart. Methods and Results: To examine the importance of endothelial leptin signaling in cardiac hypertrophy, transverse aortic constriction was used in mice with inducible endothelium-specific deletion of leptin receptors (End.LepR-KO) or littermate controls (End.LepR-WT). End.LepR-KO was associated with improved left ventricular function (fractional shortening, 28.4% versus 18.8%; P =0.0114), reduced left ventricular dilation (end-systolic inner left ventricular diameter, 3.59 versus 4.08 m…

AngiogenesisAdipose tissueAdipokineCardiomegaly030204 cardiovascular system & hematologyVentricular Function Left03 medical and health sciences0302 clinical medicineAutophagyMedicineAnimalsHumansGenetic Predisposition to Disease030212 general & internal medicineProtein kinase BCells Cultured2. Zero hungerPressure overloadHeart FailureMice KnockoutLeptin receptorNeovascularization Pathologicbusiness.industryLeptinMyocardiumTOR Serine-Threonine KinasesAutophagyEndothelial CellsFibrosisCell biologyDisease Models AnimalPhenotypeReceptors LeptinFemaleCardiology and Cardiovascular MedicinebusinessProto-Oncogene Proteins c-aktGene DeletionSignal TransductionCirculation. Heart failure
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Gauge-origin independent calculation of magnetizabilities and rotational g tensors at the coupled-cluster level.

2007

An implementation of the gauge-origin independent calculation of magnetizabilities and rotational g tensors at the coupled-cluster (CC) level is presented. The properties of interest are obtained as second derivatives of the energy with respect to the external magnetic field (in the case of the magnetizability) or with respect to magnetic field and rotational angular momentum (in the case of the rotational g tensor), while gauge-origin independence and fast basis-set convergence are ensured by using gauge-including atomic orbitals (London atomic orbitals) as well as their extension to treat rotational perturbations (rotational London atomic orbitals). The implementation within our existing …

Angular momentumCoupled clusterMagnetic momentAtomic orbitalChemistryQuantum mechanicsGeneral Physics and AstronomyRotational transitionRotational temperatureTensorPhysical and Theoretical ChemistryAtomic physicsRotational partition functionThe Journal of chemical physics
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Solution of the Skyrme-Hartree–Fock–Bogolyubovequations in the Cartesian deformed harmonic-oscillator basis. (VIII) hfodd (v2.73y): A new version of …

2017

We describe the new version (v2.73y) of the code HFODD which solves the nuclear Skyrme Hartree-Fock or Skyrme Hartree-Fock-Bogolyubov problem by using the Cartesian deformed harmonic-oscillator basis. In the new version, we have implemented the following new features: (i) full proton-neutron mixing in the particle-hole channel for Skyrme functionals, (ii) the Gogny force in both particle-hole and particle-particle channels, (iii) linear multi-constraint method at finite temperature, (iv) fission toolkit including the constraint on the number of particles in the neck between two fragments, calculation of the interaction energy between fragments, and calculation of the nuclear and Coulomb ene…

Angular momentumNuclear Theory[PHYS.NUCL]Physics [physics]/Nuclear Theory [nucl-th]SYMMETRYNuclear TheoryHartree–Fock methodGeneral Physics and AstronomyFOS: Physical sciencesGogny forceSkyrme interactionNuclear density functional theorySelf-consistent mean-field01 natural sciences114 Physical sciencesNuclear Theory (nucl-th)Energy density functional theorySYSTEMSQuantum mechanics0103 physical sciences010306 general physicsHarmonic oscillator[ PHYS.NUCL ] Physics [physics]/Nuclear Theory [nucl-th]PhysicsHartree–Fock–Bogolyubovta114010308 nuclear & particles physicsAugmented Lagrangian methodInteraction energyAngular-momentum projection113 Computer and information sciencesHardware and ArchitecturePairingIsospintheoretical nuclear physicsSelf-consistent mean fieldHartree-Fock-BogolyubovPairing correlations
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Thouless-Valatin Rotational Moment of Inertia from the Linear Response Theory

2017

Spontaneous breaking of continuous symmetries of a nuclear many-body system results in appearance of zero-energy restoration modes. Such modes introduce a non-physical contributions to the physical excitations called spurious Nambu-Goldstone modes. Since they represent a special case of collective motion, they are sources of important information about the Thouless-Valatin inertia. The main purpose of this work is to study the Thouless-Valatin rotational moment of inertia as extracted from the Nambu-Goldstone restoration mode that results from the zero-frequency response to the total angular momentum operator. We examine the role and effects of the pairing correlations on the rotational cha…

Angular momentumNuclear Theorymedia_common.quotation_subjectNuclear TheoryFOS: Physical sciencesRotary inertiaInertia114 Physical sciences01 natural sciencesbinding energy and massesMoment of inertia factorNuclear Theory (nucl-th)symbols.namesake0103 physical sciences010306 general physicsRotational partition functionEuler's equationsEQUATIONSmedia_commonPhysicsta114nuclear density functional theory010308 nuclear & particles physicstiheysfunktionaaliteoriacollective modelsMoment of inertianuclear structure and decayssuprajuoksevuusRotational energyClassical mechanicssuperfluiditysymbolsydinfysiikka
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Local Berry curvature signatures in dichroic angle-resolved photoelectron spectroscopy from two-dimensional materials

2020

Orbital polarization and Berry curvature signatures are mapped out by circular dichroism in angle-resolved photoemission.

Angular momentumtopologyAb initioPhysics::OpticsPosition and momentum spaceAngle-resolved photoemission spectroscopy02 engineering and technologyDichroic glass01 natural sciencesSettore FIS/03 - Fisica Della MateriaCondensed Matter::Materials ScienceQuantum mechanicsCondensed Matter::Superconductivity0103 physical sciences010306 general physicsResearch ArticlesPhysicsMultidisciplinaryPhysicsSciAdv r-articles021001 nanoscience & nanotechnologyARPESCondensed Matter PhysicsDensity functional theoryCondensed Matter::Strongly Correlated ElectronsBerry connection and curvatureMathematics::Differential Geometry0210 nano-technologyGround stateResearch Article
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Scope and Limitations of Baird's Theory on Triplet State Aromaticity: Application to the Tuning of Singlet–Triplet Energy Gaps in Fulvenes

2007

Utilizing Baird's theory on triplet state aromaticity, we show that the singlet-triplet energy gaps (DeltaE(ST)) of pentafulvenes are easily varied through substitution by as much as 36 kcal mol(-1). This exploits the fact that fulvenes act as aromatic chameleons in which the dipoles reverse on going from the singlet ground state (S(0)) to the lowest pipi* triplet state (T1); thus, their electron distributions are adapted so as to achieve some aromaticity in both states. The results are based on quantum chemical calculations with the OLYP density functional theory method and the CASPT2 ab initio method, as well as spectroscopic determination of DeltaE(ST) by triplet sensitization. The findi…

Aniline CompoundsMolecular StructureOrganic ChemistryTemperatureAb initioAromaticityCyclopentanesGeneral ChemistryElectronAlkenesCarbon DioxideHydrogen-Ion ConcentrationHydrocarbons AromaticCatalysischemistry.chemical_compoundchemistryAb initio quantum chemistry methodsChemical physicsComputational chemistryMicroscopy Electron ScanningDensity functional theorySinglet statePhysics::Chemical PhysicsTriplet stateFulveneChemistry - A European Journal
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NMR Spectroscopic Evidence for the Intermediacy of XeF3− in XeF2/F− Exchange, Attempted Syntheses and Thermochemistry of XeF3− Salts, and Theoretical…

2010

The existence of the trifluoroxenate(II) anion, XeF(3)(-), had been postulated in a prior NMR study of the exchange between fluoride ion and XeF(2) in CH(3)CN solution. The enthalpy of activation for this exchange, ΔH(⧧), has now been determined by use of single selective inversion (19)F NMR spectroscopy to be 74.1 ± 5.0 kJ mol(-1) (0.18 M) and 56.9 ± 6.7 kJ mol(-1) (0.36 M) for equimolar amounts of [N(CH(3))(4)][F] and XeF(2) in CH(3)CN solvent. Although the XeF(3)(-) anion has been observed in the gas phase, attempts to prepare the Cs(+) and N(CH(3))(4)(+) salts of XeF(3)(-) have been unsuccessful, and are attributed to the low fluoride ion affinity of XeF(2) and fluoride ion solvation in…

AnionsAcetonitrilesMagnetic Resonance SpectroscopyXenonChemistryInorganic chemistrySolvationNuclear magnetic resonance spectroscopyElectron localization functionIonInorganic ChemistryFluoridesCrystallographyMolecular geometryThermochemistryQuantum TheoryThermodynamicsSaltsDensity functional theoryPhysical and Theoretical ChemistryLone pairInorganic Chemistry
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Theoretical Study on the Photo-Oxidation and Photoreduction of an Azetidine Derivative as a Model of DNA Repair

2021

Photocycloreversion plays a central role in the study of the repair of DNA lesions, reverting them into the original pyrimidine nucleobases. Particularly, among the proposed mechanisms for the repair of DNA (6-4) photoproducts by photolyases, it has been suggested that it takes place through an intermediate characterized by a four-membered heterocyclic oxetane or azetidine ring, whose opening requires the reduction of the fused nucleobases. The specific role of this electron transfer step and its impact on the ring opening energetics remain to be understood. These processes are studied herein by means of quantum-chemical calculations on the two azetidine stereoisomers obtained from photocyc…

AnionsAcetonitrilesPyrimidineLightPhotochemistryAzetidinePharmaceutical ScienceOrganic chemistryDNA repair010402 general chemistryRing (chemistry)PhotochemistryOxetane01 natural sciencesArticleAnalytical ChemistryNucleobaseElectron transferchemistry.chemical_compoundElectron transferQUIMICA ORGANICAQD241-441AzetidineCationsredox propertiesDrug DiscoveryPhotosensitizerPhysical and Theoretical ChemistryPhotolyasering openingdensity functional theoryphotochemistry010405 organic chemistryRing openingModels Theoreticalelectron transfer0104 chemical scienceschemistryChemistry (miscellaneous)Density functional theoryMolecular MedicineAzetidinesThermodynamicsGasesazetidineOxidation-ReductionRedox propertiesMolecules
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Island Homoaromaticity in the W-Shaped 2,4-Diphospha-3-arsapentadienide Anion and Related Compounds - Theoretical and Experimental Investigations

2012

A series of anions with general formula (R2C=P)2Pn– (Pn = N, P, As, Sb; R = H, Me, CF3, SiH3, SiMe3, SiF3) was investigated theoretically at the DFT (RI-BP86/TZVP) and RI-MP2/TZVP levels of approximation. Significantly sharpened central PPnP bond angles were predicted for the species with π-acceptor R substituents. The corresponding bond angle values decrease in the order Pn = N >> P > As > Sb. This finding is in agreement with the previously published structural data for [(Me3Si)2C=P]2P–. An island homoaromaticity was proposed as a suitable explanation for the observed effect. In more detail, it consists of shifting negative charge to the electron-withdrawing terminal groups with formation…

AnionsHomoaromaticity010405 organic chemistryChemistryCharge (physics)010402 general chemistry01 natural sciencesHomoaromaticity0104 chemical sciencesIonInorganic ChemistryCrystallographyDensity functional calculationsMolecular geometryComputational chemistryAb initio quantum chemistry methodsMolecular orbitalsMoleculeMoietyMolecular orbitalAb initio calculations
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