Search results for " function"

Mutant p53 gain of function in human osteosarcoma 3AB-OS cancer stem cells

2012

The non-Gaussian distribution of galaxies gravitational fields

2016

We perform a theoretical analysis of the observational dependence between angular momentum of the galaxy clusters and their mass (richness), based on the method introduced in our previous paper. For that we obtain the distribution function of astronomical objects (like galaxies and/or smooth halos of different kinds) gravitational fields due to their tidal interaction. Within the statistical method of Chandrasekhar we are able to show that the distribution function is determined by the form of interaction between objects and for multipole (tidal) interaction it is never Gaussian. Our calculation permits to demonstrate how the alignment of galaxies angular momenta depend on the cluster richn…

The gallium anomaly revisited

2019

The gallium anomaly, i.e. the missing electron-neutrino flux from $^{37}$Ar and $^{51}$Cr electron-capture decays as measured by the GALLEX and SAGE solar-neutrino detectors, has been among us already for about two decades. We present here a new estimate of the significance of this anomaly based on cross-section calculations using nuclear shell-model wave functions obtained by exploiting recently developed two-nucleon interactions. The gallium anomaly of the GALLEX and SAGE experiments is found to be smaller than that obtained in previous evaluations, decreasing the significance from 3.0σ to 2.3σ. This result is compatible with the recent indication in favor of short-baseline ν¯e disappeara…

Mathematical Models and their Solutions for Domains of Compex Form

2014

Promocijas darbā tiek apskatīti dažādi oriģināli modeļi un to risinājumi sarežģītas formas apgabaliem. Intensīvās tērauda rūdīšanas procesi sistēmām ar ribām tiek aprakstīti ar 3D hiperbolisko, kā arī ar klasisko siltuma vadīšanas vienādojumu. Precīzā atrisinājuma iegūšanai izmantota Grīna funkciju metode un tās vispārinājums. Modernajos datoros sastopamajām sistēmām ar dubulsieniņu un dubultribu dota stacionārā un nestacionārā siltumvadīšanas problēma 2D gadījumā. Tās risinājums tiek iegūts ar konservatīvās viduvēšanas metodi, galīgo diferenču metodi un tās modifikāciju robežnosacījumiem. Piedāvāts jauns matemātiskais modelis vītola flautai, problēmas formulējumā izmantojot 1D lineāru viļņ…

The anthropogenic sealing of soils in urban areas

2009

The sealing of soils by impervious materials is, normally, detrimental to its ecological functions. Exchanges of energy, water and gases are restricted or hampered and an increasing pressure is being exerted on adjacent, non sealed areas. The negative effects span from loss of plant production and natural habitats to increased floods, pollution, and health risks and consequently higher social costs. Environmental Agencies produce periodical reports where the phenomenon of soil consumption by urban infrastructures is monitored with extremely sophisticated geographical tools but little specific research is available that describes the effects of soil sealing. This paper reviews some recent co…

A note on some fundamental results in complete gauge spaces and application

2015

We discuss the extension of some fundamental results in nonlinear analysis to the setting of gauge spaces. In particular, we establish Ekeland type and Caristi type results under suitable hypotheses for mappings and cyclic mappings. Our theorems generalize and complement some analogous results in the literature, also in the sense of ordered sets and oriented graphs. We apply our results to establishing the existence of solution to a second order nonlinear initial value problem.

Genome-wide association study identifies five loci associated with lung function

2010

Pulmonary function measures are heritable traits that predict morbidity and mortality and define chronic obstructive pulmonary disease (COPD). We tested genome-wide association with forced expiratory volume in 1 s (FEV1) and the ratio of FEV1 to forced vital capacity (FVC) in the SpiroMeta consortium (n = 20,288 individuals of European ancestry). We conducted a meta-analysis of top signals with data from direct genotyping (n ≤ 32,184 additional individuals) and in silico summary association data from the CHARGE Consortium (n = 21,209) and the Health 2000 survey (n ≤ 883). We confirmed the reported locus at 4q31 and identified associations with FEV1 or FEV1/FVC and common variants at five ad…

On Descriptive Characterizations of an Integral Recovering a Function from Its $$L^r$$-Derivative

2022

The notion of Lr-variational measure generated by a function F ∈ Lr[a, b] is introduced and, in terms of absolute continuity of this measure, a descriptive characterization of the HKr -integral recovering a function from its Lr-derivative is given. It is shown that the class of functions generating absolutely continuous Lr-variational measure coincides with the class of ACGr -functions which was introduced earlier, and that both classes coincide with the class of the indefinite HKr-integrals under the assumption of Lr-differentiability almost everywhere of the functions consisting these classes

¿Cabe hablar de una «generación de la crisis»? Discusión en torno a una noción sobreexplotada

2018

This article states that nowadays there is an overuse (or a misuse) of the «Generation» idea. The discussion among many authors over the «Generation of crisis» concept suggests that it is useful to outline the characteristics of the target of population of the collective of youth who are mainly affected by the economic and social crisis over the past years. Nevertheless, through analyzing the meanings of the «Generation of Crisis» made by Mannheim, Ortega and other classic authors, it is clear that the social class approach together with the generational one are needed to define this concrete concept. The conclusion of the articleis that both approaches are seen as underpinning their utilit…

Modulation transfer function in refractive-diffractive multifocal intraocular lenses in vitro

2007

Purpose: The optical quality of two types of multifocal, hybrid refractive-diffractive, intraocular lenses (IOL) is analyzed in vitro. Following the EN-ISO international standard, the IOLs’ modulation transfer functions (MTF) are determined for both distance and near vision. The behaviour of these curves when the pupil size varies is studied. Methods: The IOLs analyzed were: AcrySoft ResTor SN60D3 (Alcon) and Tecnis ZM900 (AMO). The MTF was calculated from the cross line-spread function recorded with the OPAL Vector System (Image Science Ltd. Oxford) by using fast Fourier transform techniques. The artificial eye model used simulates in vivo conditions of the anterior chamber including an ar…