Search results for " functioning"
showing 10 items of 285 documents
The Specific Role of Childhood Abuse, Parental Bonding, and Family Functioning in Female Adolescents With Borderline Personality Disorder.
2015
This study examined a broad variety of adverse childhood experiences in a consecutive sample of female adolescent inpatients with borderline personality disorder (BPD; n = 44) compared with a clinical control (CC; n = 47) group with mixed psychiatric diagnoses. BPD was diagnosed using a structured clinical interview; different dimensions of childhood adversity were assessed using the Childhood Experiences of Care and Abuse Questionnaire, the Parental Bonding Instrument, and the Family Assessment Device. A history of childhood adversity was significantly more common in patients with BPD than in the CC group. Using a multivariate model, sexual abuse (OR = 13.8), general family functioning (OR…
Mental health perspectives of Hunter syndrome: Case reports of two biological siblings
2016
Hunter syndrome is a rare X-linked recessive disorder caused by deficiency of the lysosomal enzyme iduronate-2-sulphatase, leading to progressive accumulation of a substance called glycosaminoglycans in nearly all cell types, tissues, and organs. Hunter syndrome presents with facial dysmorphism, airway diseases, skeletal defects, cardiomyopathies, and neuropsychiatric manifestations. Mental subnormality is a cardinal feature in Hunter syndrome. This is a progressive cognitive decline that is not amenable to enzyme replacement therapy. Due to progressive cognitive decline, training the children to improve the adaptive functioning is a challenge that creates immense stress for the caregivers.…
Chronic Spontaneous Urticaria and Type 1 Diabetes Mellitus—Does Quality of Life Impairment Always Reflect Health Danger?
2020
Background and aims: Chronic spontaneous urticaria (CSU) and diabetes mellitus type 1 (T1DM) may compromise the quality of life (QoL). We decided to compare the QoL of T1DM patients to those suffering from CSU. Materials and methods: Sixty-six patients with well-controlled T1DM (male 52%) in the mean age of (SD) 36.3 (11.09) years and 51 patients with CSU (male 33%) in the mean age of (SD) 35.8 (8.53) years were enrolled in this observational study. All the participants completed a Short-Form 36 (SF-36) QoL. Results: The QoL related to social functioning was significantly worse among CSU patients. There were differences related to gender found in the group of patients with T1DM&mdash
A new capability index for dynamic process analysis
2013
Nowadays, the trend to produce with reduced specification limits width and at a low defectives rate seems to be irreversible. In such conditions, reliable evaluation of the process capability level represents a crucial activity to assess the quality related performance of a production process. By adopting the classical approach, such evaluation is performed by verifying the process in-control condition and by evaluating suitable capability indices. However, considering the natural dynamic behavior of production processes, i.e. the process variability over the time domain, the in-control condition characterizes only a part of the production process functioning cycle, the one with the lowest …
Syntaxin13 expression is regulated by mammalian target of rapamycin (mTOR) in injured neurons to promote axon regeneration.
2014
Injured peripheral neurons successfully activate intrinsic signaling pathways to enable axon regeneration. We have previously shown that dorsal root ganglia (DRG) neurons activate the mammalian target of rapamycin (mTOR) pathway following injury and that this activity enhances their axon growth capacity. mTOR plays a critical role in protein synthesis, but the mTOR-dependent proteins enhancing the regenerative capacity of DRG neurons remain unknown. To identify proteins whose expression is regulated by injury in an mTOR-dependent manner, we analyzed the protein composition of DRGs from mice in which we genetically activated mTOR and from mice with or without a prior nerve injury. Quantitati…
An item response theory analysis of response stability in personality measurement
2001
An item response theory model of response stability is developed, based on the local independence principle. The model predicts response changes under repeated administrations of the same instrument using item and examinee parameter estimates as predictors. Real data were used to assess how the model functioned. Results indicated that the model predictions were approximately fulfilled. Limitations of the model and the empirical study are discussed.
The dawning of perioperative care in esophageal cancer
2017
The currently published paper “ Reduced fitness and physical functioning are long-term sequelae after curative treatment for esophageal cancer: a matched control study ” by Gannon et al . (1) focuses on a highly relevant topic of esophageal surgery, which has been greatly under-addressed in the past. Objective data on physical performance outcomes and health-related quality of life (HRQOL) of disease-free survivors after esophagectomy for cancer compared with a noncancer control group are rare (1). Data by Gannon et al . clearly show that disease-free survivors of curative esophageal cancer treatment display a significant compromise in physical functioning as compared to the control group, …
Structural Validity of the Foot and Ankle Outcome Score for Orthopaedic Pathologies with Rasch Measurement Theory
2022
Publisher Copyright: © 2021 The Authors A B S T R A C T Background: The Foot and Ankle Outcome Score (FAOS) is one of the most frequently used patient reported outcome measures for foot and ankle conditions. The aim is to test the structural validity of the Finnish version of the FAOS using Rasch Measurement Theory. Methods: FAOS scores were obtained from 218 consecutive patients who received operative treatment for foot and ankle conditions. The FAOS data were fitted into the Rasch model and person separation index (PSI) calculated. Results: All the five subscales provided good coverage and targeting. Three subscales presented unidimensional structure. Thirty-eight of the 42 items had orde…
The effects of sharing sustainable technology R&D on EU competition law
2022
This paper explores the significance of EU competition system in attaining envisioned sustainability targets by analysing the prospective symbiosis between European competition and patent law. Furthermore, this research evaluates both the plausible threats in the internal market stemming from lenient competition legislation as well as highlighting the apparent benefits of coordinating EU intellectual property and antitrust law to facilitate innovation. The goal of this research is to determine whether such polar opposites can indeed be merged into sustainable competition policy or will it end up fostering breeding ground for collusive behaviour in the common market.
Learning and motor and mental health profiles in pupils with Borderline Intellectual Functioning and Average Intellectual Functioning
2018
There is a lack of research addressing the study of the Borderline Intellectual Functioning (BIF) in school-aged population. In children and adolescents with BIF high rates of school complaints, movement impairments and mental health disorders have been demonstrated. This study aims at comparing learning, motor and mental health profiles showed by pupils with BIF and pupils with Average Intellectual Functioning (AIF). Participants were 19 children with BIF and 19 with AIF. Learning, motor and mental health profiles were measured by multiple tests. Results show that pupils with BIF showed lower comprehension and decoding reading abilities, lower word and non-word reading as well as lower mat…