Search results for " genetic"
showing 10 items of 7236 documents
Targeted Drug Delivery in Plants: Enzyme‐Responsive Lignin Nanocarriers for the Curative Treatment of the Worldwide Grapevine Trunk Disease Esca
2019
Abstract Nanocarrier (NC)‐mediated drug delivery is widely researched in medicine but to date has not been used in agriculture. The first curative NC‐based treatment of the worldwide occurring grapevine trunk disease Esca, with more than 2 billion infected plants causing a loss yearly of $1.5 billion, is presented. To date, only repetitive spraying of fungicides is used to reduce chances of infection. This long‐term treatment against Esca uses minimal amounts of fungicide encapsulated in biobased and biodegradable lignin NCs. A single trunk injection of <10 mg fungicide results in curing of an infected plant. Only upon Esca infection, ligninolytic enzymes, secreted by the Esca‐associated fu…
Drug Delivery in Plants: Targeted Drug Delivery in Plants: Enzyme-Responsive Lignin Nanocarriers for the Curative Treatment of the Worldwide Grapevin…
2019
In article number 1802315, Jochen Fischer, Frederik R. Wurm, and co‐workers report the first nanocarrier‐mediated drug delivery in plants. Enzyme‐degradable lignin nanocarriers are injected into the trunks of grapevine plants. They release a fungicide selectively inside of the plants and are able to cure the worldwide fungal plant disease Esca for the first time. This strategy will reduce the extensive spraying of pesticides in agriculture. Image credit: Katharina Maisenbacher.
Applying an operating model for the environmental risk assessment in Italian Sites of Community Importance (SCI) of the European Commission Habitats …
2013
The fast development of agro-biotechnologies asks for a harmonized approach in risk analysis of GMO's releases, where "risk analysis" entails the assessment, management and communication of risk. Risk assessment consists in the evaluation of the likelihood that a hazard occurs, associated with the presence of the receptor(s) in the receiving environment, and the determination of their potential degree of exposure to the hazard. The whole process has to be both science based and applied case by case, and it involves a very complicated procedure that needs to be transformed in an operational and standardized tool. Beginning in 2003, an expert group on behalf of the Italian Ministry of the Env…
Clinical characteristics and predictors of death among hospitalized patients infected with SARS‑CoV‑2 in Sicily, Italy: A retrospective observational…
2022
Since late December 2019, severe acute respiratory syndrome coronavirus 2 has spread across the world, which resulted in the World Health Organization declaring a global pandemic. Coronavirus disease 2019 (COVID-19) presents a highly variable spectrum with regard to the severity of illness. Most infected individuals exhibit a mild to moderate illness (81%); however, 14% have a serious disease and 5% develop severe acute respiratory distress syndrome (ARDS), requiring intensive care support. The mortality rate of COVID-19 continues to rise across the world. Data regarding predictors of mortality in patients with COVID 19 are still scarce but are being actively investigated. The present multi…
Hard to catch: Experimental evidence supports evasive mimicry
2021
Most research on aposematism has focused on chemically defended prey, but the signalling difficulty of capture remains poorly explored. Similar to classical Batesian and Müllerian mimicry related to distastefulness, such ‘evasive aposematism' may also lead to convergence in warning colours, known as evasive mimicry. A prime candidate group for evasive mimicry areAdelphabutterflies, which are agile insects and show remarkable colour pattern convergence. We tested the ability of naive blue tits to learn to avoid and generalizeAdelphawing patterns associated with the difficulty of capture and compared their response to that of birds that learned to associate the same wing patterns with distast…
Microbiome and Probiotics in Acne Vulgaris—A Narrative Review
2022
Acne vulgaris is a chronic disease characterised by the appearance of eruptions such as whiteheads, blackheads, pustules, papules, and cysts. Among factors that cause acne vulgaris are the abnormal keratinisation of the sebaceous canal, bacterial colonisation (Cutibacterium acnes), increased sebum production, genotypic factors, and hormonal disorders. Treatment is often long and tedious, and can lead to a reduction in quality of life and social isolation. The intestinal microbiota is greatly important in the formation of acne lesions. It is also responsible for the proper immunity of the organism. Acne is a disease that can be related to the condition of the digestive tract and its microbio…
Reported prevalence of health conditions that affect drivers
2017
Drivers’ health and fitness are essential factors in order to predict performance outcomes and to promote road safety. It is a demonstrated fact that drivers with (physical and mental) health impairments or illnesses have more probabilities of being involved in traffic crashes and suffering (or causing) several injuries. The general objective of this study was to examine the prevalence of adverse health conditions that may affect Spanish drivers and its perceived impact on driving fitness. It was used a sample of 1,200 Spanish drivers (666 men and 534 women). The only selection criteria were to be in possession of any type of driving license for vehicles other than motorcycles and to drive …
Spatial variation in the evolutionary potential and constraints of basal metabolic rate and body mass in a wild bird
2023
An organism's energy budget is strongly related to resource consumption, performance, and fitness. Hence, understanding the evolution of key energetic traits, such as basal metabolic rate (BMR), in natural populations is central for understanding life-history evolution and ecological processes. Here we used quantitative genetic analyses to study evolutionary potential of BMR in two insular populations of the house sparrow (Passer domesticus). We obtained measurements of BMR and body mass (Mb) from 911 house sparrows on the islands of Leka and Vega along the coast of Norway. These two populations were the source populations for translocations to create an additional third, admixed ‘common ga…
Evolutionary trade-offs in a small mammal : a quantitative genetics approach
2017
Limited resources force individuals to trade-off between life-history traits. A vast diversity of life-history strategies, which optimally combine life history traits, can be found. Knowledge of the genetic basis of this phenotypic variation is key to understanding evolutionary processes. I approached life-history evolution by estimating quantitative genetic parameters for a set of life-history traits in the bank vole (Myodes glareolus). The work is based on a laboratory-kept colony subjected to two-way selection for litter size (High- (H) and Low- (L) lines). Costs of the created reproductive strategies were observed in natural conditions. Selection increased the difference in litter size …
Genetics of condition and sexual selection
2007
FM Tarmo Ketolan ekologian ja ympäristönhoidon väitöskirjan ”Genetics of Condition and Sexual Selection” (Kunnon ja seksuaalivalinnan genetiikka) tarkastustilaisuus Jyväskylän yliopistossa. Vastaväittäjänä professori Juha Merilä (Helsingin yliopisto) ja kustoksena dosentti Janne Kotiaho.Linkki väitöksen pdf-versioon tiedotteen lopussa.FM Tarmo Ketola havaitsi väitöstutkimuksessaan, että geneettisesti huonolaatuiset sirkkayksilöt pystyvät käyttämään vähemmän energiaa aktiviteetteihin kuin hyvälaatuiset. Koska sisäsiitos lisäsi perusenergiankulutusta eli ruumiintoimintojen ylläpitoon kulutettua energiaa, se heikensi yksilöiden kuntoa.– Aiemmin on oletettu, että huonolaatuisilla yksilöillä on …