Search results for " graf"

showing 10 items of 456 documents

Tunica vaginalis Free Grafts for Closure of Urethrocutaneous Fistulas

1990

In 32 patients a tunica vaginalis free graft was used for closure of urethrocutaneous fistulas (n = 26) or complicated hypospadias repair (n = 6). All patients had at least one operation (average 3.9) for urethral reconstruction prior to this procedure. 12 patients had recurrent fistulas (average 2.2). The technique proved to be very successful. Only 2 patients had to undergo subsequent reoperation for recurrent fistulas. The use of a free tunica vaginalis graft interposed between skin and urethra is our method of choice in the repair of recurrent or complicated urethrocutaneous fistulas.

AdultMalemedicine.medical_specialtyPenile DiseasesAdolescentUrinary FistulaUrologyEpispadiasPostoperative ComplicationsTestisUrethral DiseasesMethodsHypospadias repairHumansMedicineChildHypospadiasbusiness.industryFree graftTunica vaginalisTunica vaginalis testismedicine.diseaseSurgerymedicine.anatomical_structureUrethraHypospadiasChild PreschoolbusinessUrologia Internationalis
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Lattice Corneal Dystrophy Type 1

2014

PURPOSE To evaluate the question whether lattice corneal dystrophy type 1 (LCD1) is of epithelial or stromal origin. METHODS The landmark of advanced LCD1 shows central superficial haze and paracentral stromal lattice lines. In 16 eyes of 8 affected individuals of 2 families, a penetrating keratoplasty was performed. The follow-up was 8 to 16 years after penetrating keratoplasty. Slit-lamp documentation of the patients was evaluated in direct and indirect illumination with dilated pupil to assess the horizontal and vertical pattern of new deposits on the corneal graft. Three affected patients of 2 families are demonstrated in detail. A DNA analysis was performed. RESULTS Gene identification…

AdultMalemedicine.medical_specialtyStromal cellCorneal StromaDNA Mutational AnalysisCorneal graftCorneal KeratocytesCorneal erosionDirect illuminationTransforming Growth Factor betaOphthalmologyTGFBI genemedicineHumansCorneal Dystrophies HereditaryExtracellular Matrix Proteinsbusiness.industryEpithelium Cornealmedicine.diseaseeye diseasesOphthalmologyMutationLattice corneal dystrophyFemalebusinessKeratoplasty PenetratingTGFBICornea
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Lung Preservation With Perfadex or Celsior in Clinical Transplantation: A Retrospective Single-Center Analysis of Outcomes.

2015

BACKGROUND Despite improvement of lung preservation by the introduction of low-potassium dextran (LPD) solution, ischemia-reperfusion injury remains a major contributor to early post-lung transplant graft dysfunction and mortality. After favorable experimental data, Celsior solution was used in our clinical lung transplant program. Data were compared with our historic LPD cohort. METHODS Between January 2002 and January 2005, 209 consecutive lung transplantations were performed with LPD. These were compared to 208 transplants between February 2005 and September 2007 with Celsior. Endpoints included posttransplant PaO2/FiO2 ratio at different timepoints after intensive care unit (ICU) admiss…

AdultMalemedicine.medical_specialtyTime FactorsOrgan Preservation SolutionsBronchiolitis obliteransKaplan-Meier EstimateSingle CenterDisaccharidesDisease-Free Survivallaw.inventionElectrolytesGlutamateslawRisk FactorsGermanymedicineHumansHistidineMannitolCitratesProportional Hazards ModelsRetrospective StudiesTransplantationLungProportional hazards modelbusiness.industryRetrospective cohort studyOrgan PreservationLength of StayMiddle Agedmedicine.diseaseIntensive care unitGlutathioneRespiration ArtificialSurgeryTransplantationIntensive Care Unitsmedicine.anatomical_structureTreatment OutcomeCohortBronchiolitisFemalePrimary Graft DysfunctionbusinessLung TransplantationTransplantation
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Multiple periscope and chimney grafts to treat ruptured thoracoabdominal and pararenal aortic aneurysms

2011

Purpose: To report midterm outcomes after urgent endovascular repair of ruptured pararenal or thoracoabdominal aortic aneurysms using multiple periscope and chimney grafts to preserve renovisceral branch perfusion and facilitate aneurysm exclusion. Methods: Nine consecutive men (mean age 72614 years, range 40–88) presenting with ruptured thoracoabdominal (n56), pararenal (n52), or infrarenal (n51) aortic aneurysm underwent urgent endovascular repair with at least 1 periscope graft delivered via a transfemoral access; chimney grafts were installed from an axillary access. In all, 17 periscope and 7 chimney grafts were used to reperfuse 11 renal and 13 visceral arteries in the 9 patients. The…

AdultMalemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentAortic RuptureLess invasive610 Medicine & healthRuptured Aortic AneurysmProsthesis DesignEndovascular aneurysm repairSettore MED/22 - Chirurgia VascolareAortography2705 Cardiology and Cardiovascular Medicinelaw.inventionBlood Vessel Prosthesis ImplantationlawmedicineHumans2741 Radiology Nuclear Medicine and ImagingRadiology Nuclear Medicine and imagingChimneyAgedRetrospective Studiesendodebranching renovisceral arteries chimney graft periscope graft stentgraft endograft ruptured aortic aneurysm ruptured thoracoabdominal aortic aneurysm ruptured pararenal aortic aneurysm ruptured AAA endovascular aneurysm repairAged 80 and overAortic Aneurysm Thoracicbusiness.industry10042 Clinic for Diagnostic and Interventional RadiologyEndovascular ProceduresChimney graftBlood flowMiddle AgedSurgeryBlood Vessel Prosthesis10020 Clinic for Cardiac Surgery2746 SurgeryTreatment Outcomecardiovascular systemSurgeryFemaleStentsRadiologyPeriscopeCardiology and Cardiovascular MedicinebusinessTomography X-Ray ComputedAortic Aneurysm Abdominal
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Crucial Role of Extended Criteria Donors in Deceased Donor Single Kidney Transplantation to Face Chronic Shortage in the Heart of the Mediterranean B…

2019

Background: The gap between organ availability and patients on the waiting list for deceased donor kidney transplants has resulted in the wide use of extended criteria donors (ECDs).We aimed to compare the surgical outcomes of single kidney transplantation (KT) performed at our institute with standard criteria donor (SCD) or ECD grafts, according to the Organ Procurement and Transplantation Network definition. Patients and methods. Our retrospective analysis studied 115 adult recipients of KT from January 2016 to July 2018, with kidney grafts procured from adult donors after brain or circulatory death, performed at our institute. Among the 2 recipients’ groups, we compared the incidence of …

AdultMalemedicine.medical_specialtyTissue and Organ ProcurementDelayed Graft FunctionSingle CenterMedicineHumansSurvival analysisKidney transplantationRetrospective StudiesTransplantationKidneyContinental Population Groupsbusiness.industryIncidence (epidemiology)IncidenceGraft SurvivalRacial GroupsRetrospective cohort studyMiddle Agedmedicine.diseaseKidney TransplantationSurvival AnalysisTissue DonorsSurgeryTransplantationsurgical procedures operativemedicine.anatomical_structureTreatment OutcomeSurgeryFemalebusinessBody mass indexTransplantation proceedings
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Durability of open popliteal artery aneurysm repair

2014

Objective The objective of this study was to analyze our long-term results after open surgery for popliteal artery aneurysm. Methods Records of patients who received surgery between 1998 and 2010 were retrieved from a computerized database and analyzed retrospectively. End points of the study were perioperative mortality and morbidity and patency and limb salvage rate. Results Two hundred and six popliteal aneurysms (median diameter, 30 mm; interquartile range, 18 mm) were treated (161 elective, 45 emergent) in 154 patients (mean age, 67 ± 11 years) using vein grafts (82%) via the medial approach (92%). Above-knee popliteal artery (45%) and below-knee popliteal artery (65%) were the predomi…

AdultMalemedicine.medical_specialtyUmbilical VeinsLimb salvageVein graftInterquartile rangemedicine.arteryMedicineHumansPopliteal ArteryAgedRetrospective StudiesComputerized databasesAged 80 and overUltrasonography Doppler Duplexbusiness.industryOpen surgeryAnastomosis SurgicalPopliteal artery aneurysmAngiography Digital SubtractionPerioperativeMiddle AgedPlastic Surgery ProceduresAneurysmPopliteal arterySurgeryTreatment OutcomeAnesthesiaFemaleSurgerybusinessCardiology and Cardiovascular MedicineVascular Surgical ProceduresMagnetic Resonance AngiographyFollow-Up StudiesForecastingJournal of Vascular Surgery
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The tongue as an alternative donor site for graft urethroplasty: A pilot study

2006

Purpose: Urethroplasty with a buccal mucosal graft provides excellent clinical results but it may also cause oral complications in some cases. The mucosa covering the lateral and under surface of the tongue is identical in structure with that lining the rest of the oral cavity. We evaluated LMGs for urethroplasty.Materials and Methods: From January 2001 to September 2004, 8 men 34 to 65 years old (mean age 46.1) with urethral strictures 1.5 to 4.5 cm long were selected for 1-stage dorsal onlay urethroplasty. The site of the harvest graft was the lateral mucosal lining of the tongue. Postoperatively all patients were followed with urethrography, uroflowmetry, cystourethrography and flexible …

AdultMalemedicine.medical_specialtyUrethral strictureUrologyUrethroplastymedicine.medical_treatmentTransplantsPilot ProjectsTransplantTongueUrethraTonguemedicineHumansAlternative donorUrethral strictureAgedbusiness.industryMouth MucosaMucous membraneMucous membraneBuccal administrationMiddle Agedmedicine.diseaseSurgerymedicine.anatomical_structureUrethraMucosal graftUrethra; Urethral stricture; Tongue; Mucous membrane; TransplantsUrologic Surgical Proceduresbusiness
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Lingual mucosal graft urethroplasty for anterior urethral reconstruction.

2008

Objective: Evaluate the use of lingual mucosal graft (LMG) in anterior urethral strictures.Methods: From January 2001 to December 2006, 29 men (mean age, 48.5 yr) with anterior urethral strictures underwent graft urethroplasty with LMG. The mean length of stricture was 3.6 cm. Patients with bulbar, penile, or bulbopenile strictures received one-stage dorsal free graft urethroplasties. In patients with failed hypospadias repair we performed a two-stage urethroplasty. Criteria for successful reconstruction were spontaneous voiding with no postvoid residual urine and no postoperative instrumentation of any kind. Clinical assessment included the donor site morbidity.Results: Mean follow-up was …

AdultMalemedicine.medical_specialtyUrethroplastyUrologic Surgical Procedures MaleUrethral strictureUrologyUrethroplastymedicine.medical_treatmentTransplantsFree flapTransplantUrethral stenosisUrethraTongueTonguemedicineHumansOral mucosaAgedBuccal mucosa Free grafts Hypospadias Oral mucosa Tongue Transplants Urethra Urethral stricture UrethroplastyUrethral StrictureHypospadiasbusiness.industryMouth MucosaFree graftMiddle AgedPlastic Surgery Proceduresmedicine.diseaseSurgerymedicine.anatomical_structureUrethraFree graftsTreatment OutcomeHypospadiasHypospadiaBuccal mucosaOral mucosabusinessEuropean urology
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Use of Hepatitis C-Positive Deceased Liver Donors in Response to the Organ Shortage in an Endemic Area

2017

The region of Sicily, Italy, is witnessing a chronic organ shortage. Thus, to face this critical issue, the use of marginal donors has increased over time. An example of marginal donor expansion is the use of liver donors who are positive for the hepatitis C antibody (HCV+) for HCV+ patients requiring liver transplantation (LT). In view of new advances in HCV therapy, including direct-acting agents (DAAs) to treat HCV in the post-transplant setting, our study focused on a monocentric experience in a series of consecutive LTs performed in adult patients receiving HCV+ liver donor allografts. From 2003 to 2016 at our institute we performed 10 LT using HCV+ deceased donors. In particular, the …

AdultMalemedicine.medical_specialtymedicine.medical_treatmentHepacivirusHepacivirusLiver transplantationAntiviral AgentsGastroenterologyDonor SelectionFibrosisInternal medicinemedicineHumansAntiviral Agents; Donor Selection; Hepacivirus; Liver TransplantationSurvival rateAgedRetrospective StudiesTransplantationbiologybusiness.industryDonor selectionGraft SurvivalGeneral MedicineHepatitis CMiddle Agedmedicine.diseasebiology.organism_classificationHepatitis CTissue DonorsIshak ScoreLiver TransplantationSurvival RateItalyLiverFemaleSteatosisbusinessAntiviral agents Donor selection Hepacivirus Liver transplantation Adult Graft Survival Hepatitis C Liver Liver Transplantation Middle Aged Retrospective Studies Survival Rate Tissue DonorsAnnals of Transplantation
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Vascular Grafts and Flow-through Flaps for Microsurgical Lower Extremity Reconstruction

2017

Background The use of vascular grafts is indicated in case of insufficient pedicle length or for complex defects involving both soft tissues and vessels. Venous grafts (for both venous and arterial reconstructions) and arterial grafts (arterial reconstruction) can be used. This study retrospectively evaluated the needs for vascular reconstruction and its results in a clinical series of lower limb reconstructions with microsurgical free flaps. Materials and Methods From 2010 to 2015, a total of 16 vascular grafts or flow-through flaps were used in 12 patients out of a total of 150 patients undergoing microsurgical reconstruction (8%). Arterial reconstruction was performed in seven cases (si…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentSettore MED/19 - Chirurgia PlasticaScarsVein graft030204 cardiovascular system & hematology030230 surgerySurgical Flapslower limb reconstruction03 medical and health sciences0302 clinical medicinemedicine.arterymedicineHumansRadial arteryUlnar arteryAgedRetrospective Studiesbusiness.industryvascular graftGraft SurvivalSoft tissueRetrospective cohort studymicrosurgeryMiddle AgedPlastic Surgery ProceduresMicrosurgerySurgeryTreatment OutcomeBypass surgeryFemaleSurgerymedicine.symptombusinessVascular Surgical ProceduresLeg Injuries
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