Search results for " hip"
showing 10 items of 381 documents
Prenatal low-level exposure to CO alters postnatal development of hippocampal nitric oxide synthase and haem-oxygenase activities in rats.
2001
The effects of prenatal CO exposure (150 ppm from days 0 to 20 of pregnancy) on the postnatal development of hippocampal neuronal NO synthase (nNOS) and haem-oxygenase (HO-2) isoform activities in 15-, 30- and 90-d-old rats were investigated. Unlike HO-2, hippocampal nNOS activity increased from postnatal days 15-90 in controls. Prenatal CO produced a long-lasting decrease in either nNOS or HO-2. The results suggest that the altered developmental profile of hippocampal nNOS and HO-2 activities could be involved in cognitive deficits and long-term potentiation dysfunction exhibited by rats prenatally exposed to CO levels resulting in carboxyhaemoglobin (HbCO) levels equivalent to those obser…
Revisió sistemàtica dels tractaments per al trastorn d'identitat dissociatiu
2015
La finalitat d'aquesta revisió sistemàtica va ser determinar l'eficàcia dels mètodes terapèutics per al Trastorn d'Identitat Dissociatiu (DID), en què es diferencia entre tractament psicoterapèutic i farmacològic, així com el tractament per a pacients amb comorbilitat. D'un total de 1.209 referències obtingudes a la base de dades PsycInfo, s'hi seleccionaren 15 estudis a partir dels criteris de selecció establerts prèviament. Un dels estudis s'ha obtingut a la base de dades Web of Science. Els criteris seguits per seleccionar els articles són aquells amb pacients adults diagnosticats de DID que rebien alguna o ambdues modalitats terapèutiques esmentades més amunt, i foren rebutjats aquells …
The von Hippel-Lindau tumor suppressor gene
1997
Abstract The von Hippel-Lindau (VHL) disease is an inherited tumor susceptibility syndrome featuring a high variety of benign and malignant tumors. The gene has been localized and cloned at 3p25-26. Recent functional analysis defined the VHL gene product as an inhibitor of the transcription elongation process. Its possible involvement in the vascularization process may explain the histologic features of VHL tumors providing insight into basic mechanism of tumorigenesis. Direct genetic testing is available for patients affected with VHL. Seventy to eighty percent of the germline mutations expected could be detected. As first geno/phenotype correlations have been established, we are now begin…
Conventional karyotype, nucleolar organizer regions and genome size in five Mediterranean species of Syngnathidae (Pisces, Syngnathiformes)
1998
Conventional karyotypes, NOR-bearing chromosomes by means of silver impregnation and genome size were investigated in five Mediterranean species in three genera of the Syngnathidae. A karyotype of 48 subtelocentric-acrocentric chromosomes was found in the seahorse Hippocampus hippocampus (FN=48) while a diploid value of 44 occurred in H. guttulatus (2 sm-m+42 a; FN=46) and the pipefish Syngnathus abaster (44 a; FN=44) and S. typhle (44 a; FN=44). The pipefish Nerophis ophidion, possessing a diploid chromosomal set of 58 made up of 50 meta-submetacentric and eight subteloacrocentric elements (FN=108) and a genome size three to four times larger than those known to date, differs cytogenetical…
Multiple sex-chromosome system and other karyological characterizations of Pterotrachea hippocampus (Mollusca: Mesogastropoda)
1993
Two modal diploid numbers of chromosomes were found for Pterotraches hippocampus Philippi (Mollusca: Mesogastropoda) collected from the Gulf of Palermo in 1990: 2n=31 and 32 for males and females, respectively. This, along with other karyological characteristics such as the occurrence of a trivalent configuration at diakinesis and two types of metaphase-II spreads in spermatocytes, supports the notion that a X1X2Y♂/X1X1X2X2♀ sex mechanism operates in the species investigated here. Silver nitrate procedure revealed an intraindividual variation in the Ag-staining pattern occurring in this species. The majority of the chromosome pair displayed terminal and/or interstitial heterochromatic block…
Detection of a novel germline mutation in the von Hippel-Lindau tumour-suppressor gene by fluorescence-labelled base excision sequence scanning (F-BE…
1999
The von Hippel Lindau (VHL) syndrome is an inherited multi-tumour disorder characterised by clinical heterogeneity and high penetrance. The VHL gene has been shown to be a tumour-suppressor gene. A carrier of a germline mutation will be predisposed to a high variety of benign and malign tumours affecting different organ systems. As treatment of VHL malformations in presymptomatic stages will improve significantly the clinical outcome and the patient's quality of life, early and unambiguous detection of a germline mutation is mandatory. Direct sequencing especially of large genes might be laborious and time consuming. Therefore, most laboratories apply single strand conformational polymorphi…
Aproximación a la lengua de los tratados hipocráticos De fistulis y De haemorrhoidibus
2003
A partir de una aproximación previa en un trabajo anterior a propósito de aspectos fonéticos y morfológicos en dos tratados quirúrgicos del Corpus Hippocraticum, De fistulis y De haemorrhoidibus, en el presente artículo se quiere continuar esta labor en el terreno de la sintaxis y el vocabulario, con vistas a poner de relieve algunos rasgos de griego helenístico que, claramente, aparecen en estos tratados. Todo ello refuerza la opinión de que estos tratados son obras de pleno siglo IV a. C., De haemorrhoidibus probablemente de mediados de siglo y De fistulis quizá algo anterior. From a previous approach about phonetic and morphological features in the Hippocratic treatrises De fistulis and …
Asociación de pravastatina y fenofibrato (Pravafenix®). Estudios de seguridad
2014
Resumen Aunque el colesterol unido a lipoproteinas de baja densidad (cLDL) es el objetivo primario de tratamiento para reducir el riesgo cardiovascular, el incremento de trigliceridos y el descenso del colesterol unido a lipoproteinas de alta densidad (cHDL) constituyen el denominado riesgo cardiovascular residual. El tratamiento con estatinas asociado a fibratos es una posibilidad real de tratamiento del riesgo cardiovascular total. Sin embargo, esta asociacion puede con frecuencia asociarse a efectos adversos, especialmente musculares y hepaticos. Por sus caracteristicas farmacologicas, la asociacion de pravastatina con fenofibrato puede ser eficaz y segura, con escasos efectos secundario…
The Symmetry and Predictive Factors in Two-Stage Bilateral Hip Replacement Procedures
2021
Background: Approximately 10–25% of total hip replacement patients undergo a bilateral procedure. The purpose of this study was to compare selected parameters associated with the first and second hip arthroplasty in patients undergoing two-stage treatment due to bilateral hip osteoarthritis and establish the predictive factors for the second procedure. Methods: This study compared the data on bilateral total hip replacement surgeries conducted in the period between 2017 and 2021 (42 patients). The following parameters from the first and second procedure were compared: the prosthetic stem, head, and insert cup size
Aspectos fonéticos y morfológicos de dos tratados del Corpus Hippocraticum
2002
Entre otras consideraciones, en este artículo se quieren poner de relieve algunos rasgos lingüísticos de los tratados hipocráticos De fistulis y De haemorrhoidibus, dentro del grupo de los tratados quirúrgicos de la Colección, con vistas a mostrar cómo se entreveran en ellos rasgos jónicos y áticos en dirección al griego helenístico. En nuestra opinión, estos tratados son obras de pleno siglo IV a. C., De haemorrhoidibus probablemente de mediados de siglo y De fistulis quizá algo anterior. Among other considerations, in this paper the author tries to point out some specific and linguistic features of the Hippocratic treatrises De fistulis and De haemorrhoidibus, both among the surgical trea…