Search results for " hydrolysis"

showing 2 items of 142 documents

Intracellular acidosis in murine fibrosarcomas coincides with ATP depletion, hypoxia, and high levels of lactate and total Pi

1994

Bioenergetic and metabolic status of murine FSaII tumours were evaluated using 31P MRS, acid extracts ('global' techniques) and quantitative bioluminescence ('microregional' assay). Data obtained from s.c. tumours of varying sizes (44-600 mm3) have been correlated with the oxygenation status evaluated using O2-sensitive needle electrodes. beta-NTP/Pi and phosphocreatine (PCr)/Pi ratios derived from 31P MRS were positively correlated to the median tissue pO2 values. pH declined during growth with intracellular acidosis being evident in tumours > 350 mm3. Whereas lactic acid formation greatly contributed to this decline in small- and medium-sized tumours, ATP hydrolysis and slowing down of th…

medicine.medical_specialtyMagnetic Resonance SpectroscopyAlkalosisPhosphocreatineBioenergeticsFibrosarcomaAdenylate kinaseBiologyPhosphatesPhosphocreatineMicechemistry.chemical_compoundAdenosine TriphosphateATP hydrolysisInternal medicinemedicineAnimalsRadiology Nuclear Medicine and imagingLactic AcidEnergy chargeSpectroscopyAcidosisMice Inbred C3HHydrogen-Ion Concentrationmedicine.diseaseCell HypoxiaOxygenGlucoseEndocrinologychemistryLactatesMolecular MedicineFemalemedicine.symptomAcidosisEnergy MetabolismIntracellularNMR in Biomedicine
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Optimization of the Red Tilapia (Oreochromis spp.) Viscera Hydrolysis for Obtaining Iron-Binding Peptides and Evaluation of In Vitro Iron Bioavailabi…

2020

Iron deficiencies continue to cause significant health problems in vulnerable populations. A good strategy to combat mineral deficiency includes fortification with iron-binding peptides. This research aims to determine the optimal conditions to hydrolyze red tilapia viscera (RTV) using Alcalase 2.4 L and recovery of iron-binding protein hydrolysate. The result showed that under the optimal hydrolysis condition including pH 10, 60 &deg

protein hydrolysisHealth (social science)food.ingredientHydrolyzed proteinsurface response designMineral deficiencyPlant Sciencelcsh:Chemical technologyHealth Professions (miscellaneous)MicrobiologyArticleAlcalaseHydrolysateHydrolysisfoodmedicinelcsh:TP1-1185Food scienceCaco-2 cellsbiologyChemistryTilapiamedicine.diseasebiology.organism_classificationBioavailabilityFerritinOreochromisbiology.proteiniron bioavailabilityiron-binding activityFood ScienceFoods
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