Search results for " igiene"

showing 10 items of 754 documents

Childhood and Adolescence Cancers in the Palermo Province (Southern Italy): Ten Years (2003-2012) of Epidemiological Surveillance

2018

Italy has one of the highest paediatric cancer incidence rates in Europe. We compared cancer incidence and survival rates in children (0&ndash

MaleRegistriecancer incidencejointpoint regressionHealth Toxicology and Mutagenesislcsh:MedicineSettore MED/42 - Igiene Generale E Applicata0302 clinical medicineNeoplasmsMedicine030212 general & internal medicineRegistriesYoung adultcancer survivalChildeducation.field_of_studyIncidence (epidemiology)Incidenceepidemiological surveillancepopulation-based cancer registrieSurvival RateItaly030220 oncology & carcinogenesisChild PreschoolFemaleHumanpopulation-based cancer registriesAdolescentPopulationDisease clusterArticle03 medical and health sciencesYoung AdultHumanseducationSurvival rateSurvival analysistime trendsbusiness.industrylcsh:RPublic Health Environmental and Occupational HealthCancerInfantmedicine.diseaseCancer registrytime trendNeoplasmbusinesscancer in childhood and adolescenceDemography
researchProduct

Changes of QTc interval after opioid switching to oral methadone.

2013

Abstract A consecutive sample of patients who were switched from strong opioids to methadone in a period of 1 year was surveyed. QTc was assessed before switching (T0) and after achieving adequate analgesia and an acceptable level of adverse effects (Ts). Twenty-eight of 33 patients were switched to methadone successfully. The mean initial methadone doses at T0 were 67.1 mg/day (SD ±80.2, range 12-390). The mean QTc interval at T0 was 400 ms (SD ±30, range 330-450). The mean QTc interval at Ts (median 5 days) was 430 ms (SD ±26, range 390-500). The difference (7.7 %) was significant (p < 0.0005). Only two patients had a QTc of 500 ms. No serious arrhythmia was observed. At the linear regres…

MaleRiskCancer pain; Methadone; QT prolongation; Toxicity; Opioid switchingPainSettore MED/41 - AnestesiologiaQT prolongationSettore MED/42 - Igiene Generale E ApplicataQT intervalCONSECUTIVE SAMPLEElectrocardiographyNeoplasmsOpiate Substitution TreatmentmedicineHumansIn patientcardiovascular diseasesCancer painAdverse effectAgedToxicitybusiness.industryMiddle AgedAnalgesics OpioidLong QT SyndromeOncologyOpioidAnesthesiaToxicityLinear Modelscardiovascular systemOpioid switchingFemaleCancer painbusinessMethadoneMethadonemedicine.drug
researchProduct

Analysis of hospitalizations due to intussusception in Sicily in the pre-rotavirus vaccination era (2003–2012)

2015

Background: Intussusception is the most common cause of bowel obstruction in infants with an incidence ranging from 9-328 cases per 100,000 infants aged 0-11 months. Causes underlining this clinical manifestation are still unknown. Possible relationship with a withdrawn tetravalent rotavirus vaccine was not confirmed by post-licensure studies and actually no increased risk of intussusception was found between infants vaccinated with both the recently licensed rotavirus vaccines. Aim of this study is to analyze the intussusception hospitalizations in Sicily from 2003 to 2012 before the introduction of rotavirus universal vaccination and its possible relation with rotavirus gastroenteritis tr…

MaleRotavirusPediatricsmedicine.medical_specialtyInternational classification of diseaseIntestinal invaginationHospitalization rateSettore MED/42 - Igiene Generale E Applicatamedicine.disease_causeRotavirus InfectionsRotavirus gastroenteritiIntussusception (medical disorder)RotavirusHumansMedicineRotavirus gastroenteritisSicilyRetrospective StudiesInternational classification of diseasesbusiness.industryResearchIncidencePublic healthIncidence (epidemiology)Hospitalization ratesVaccinationInfant NewbornRotavirus VaccinesInfantRetrospective cohort studySeasonalitymedicine.diseaseRotavirus vaccineHospitalizationBowel obstructionVaccinationHospitalization rates; International classification of diseases; Intestinal invagination; Rotavirus gastroenteritis; Seasonality; Pediatrics Perinatology and Child HealthChild PreschoolPediatrics Perinatology and Child HealthFemalebusinessIntussusceptionItalian Journal of Pediatrics
researchProduct

Use of QT intervals for a more accurate diagnose of syncope and evaluation of syncope severity.

2014

Abstract BACKGROUND: This study aimed to evaluate the use of QT intervals, their diagnostic predictive value in patients with syncope and their relationship with syncope severity. METHODS: One hundred and forty nine patients with a diagnosis of syncope were admitted to Internal Medicine departments at the University of Palermo, Italy, between 2006 and 2012, and 140 control subjects hospitalised for other causes were enrolled. QT maximum, QT minimum, QTpeak, QT corrected, QT dispersion and Tpeak-to-Tend interval were compared between two groups. The paper medical records were used for scoring with San Francisco Syncope Rule (SFSR), Evaluation of Guidelines in SYncope Study (EGSYS) score and …

MaleSan Francisco Syncope Rulemedicine.medical_specialtySettore MED/09 - Medicina InternaSettore MED/42 - Igiene Generale E ApplicataTHERAPYQT intervalSyncopeRISK STRATIFICATIONElectrocardiographyPROSPECTIVE VALIDATIONDISPERSIONRisk FactorsInternal medicineSCOREmedicineHumansIn patientPREDICT PATIENTSAgedAged 80 and overFramingham Risk ScoreSERIOUS OUTCOMESmedicine.diagnostic_testbiologybusiness.industryMedical recordVENTRICULAR REPOLARIZATION; PROSPECTIVE VALIDATION; RISK STRATIFICATION; DIABETIC-PATIENTS; SERIOUS OUTCOMES; PREDICT PATIENTS; DISPERSION; GENDER; THERAPY; SCORESyncope (genus)General MedicineMiddle AgedControl subjectsbiology.organism_classificationDIABETIC-PATIENTSItalyAnesthesiaCardiologyFemaleGENDERVENTRICULAR REPOLARIZATIONbusinessElectrocardiography
researchProduct

The use of haemostatic agents in thyroid surgery: efficacy and further advantages. Collagen-Fibrinogen-Thrombin Patch (CFTP) versus Cellulose Gauze.

2013

Abstract Aim: To assess the efficacy of two widely used topical haemostatic agents: oxidised regenerated cellulose gauze and Collagen-Fibrinogen-Thrombin Patch in patients undergoing total thyroidectomy. Material of study: This was a prospective, comparative, non-randomised study in which consecutive patients undergoing total thyroidectomy for benign disease received standard treatment with no haemostatic agent, cellulose gauze, or CFTP. Main outcome measures were drainage volume 24 hours after surgical procedure and the occurrence of post-operative complications (haematoma, seroma, surgical-site infection). Results: Two hundred seventy-one (271) patients undergoing total thyroidectomy for …

MaleSurgical haemostasiThrombinFibrinogenMiddle AgedPostoperative HemorrhageSettore MED/42 - Igiene Generale E ApplicataSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheBandagesHemostasis SurgicalHemostaticsSettore MED/18 - Chirurgia GeneraleThyroidectomyHumansFemaleCollagenProspective StudiesCellulose
researchProduct

[Italy 2014: 1,000 new cancer cases every day, but mortality is decreasing].

2015

In Italy in 2014 1,000 new cancer cases every day, but mortality is decreasing

MaleSurvival Ratecancer incidenceItalyNeoplasmsHumansFemaleMorbidityMortalitySex Distributioncancer in Italy cancer registriesSettore MED/42 - Igiene Generale E ApplicataEpidemiologia e prevenzione
researchProduct

Post-vaccine measles in a child with concomitant influenza, Sicily, Italy, March 2015

2015

We describe the occurrence of measles in an 18 month-old patient in Sicily, Italy, in March 2015, who received the first dose of a measles-containing vaccine seven days before onset of prodromal symptoms. Measles virus infection was confirmed by PCR and detection of specific immunoglobulin; viral genotyping permitted the confirmation of a vaccine-associated illness. The patient had a concurrent influenza virus infection, during a seasonal epidemic outbreak of influenza.

MaleTime FactorsMeasles-Mumps-Rubella VaccineGenotypeEpidemiologyAntibodies ViralSettore MED/42 - Igiene Generale E ApplicataMeaslesPolymerase Chain ReactionVirusMeasles virusChickenpox VaccineVirologymedicineHumansVaccines CombinedGenotypingChickenpox Vaccinebiologybusiness.industryPublic Health Environmental and Occupational HealthInfantmedicine.diseasebiology.organism_classificationVirologyMEASLES INFLUENZA VACCINESImmunoglobulin MItalyImmunoglobulin MMeasles virusConcomitantbiology.proteinFemalebusinessMeasles-Mumps-Rubella VaccineMeasles
researchProduct

Universal rotavirus vaccination program in Sicily: Reduction in health burden and cost despite low vaccination coverage

2018

ABSTRACT Rotavirus is considered the main cause of severe gastroenteritis and nosocomial infections in Pediatric units, especially during late winter and early spring season in temperate region. In 2013 Sicilian Region, for the first time in Italy, introduced universal Rotavirus vaccination. This study aims to estimate health and economic impact on rotavirus Gastroenteritis (RVGE) among children aged 0–59 months in Sicily, after rotavirus vaccine introduction. We analyzed hospital discharge records including a diagnosis of RVGE occurred from 1st January 2009 to 31st December 2016 among hospitalized children aged 0 to 59 months, residents in Sicily. RVGEs were defined as all hospitalizations…

MaleVaccination CoverageImmunologyRotavirus gastroenteritisSettore MED/42 - Igiene Generale E Applicatamedicine.disease_causeRotavirus vaccinationRotavirus Infectionscost impact analysis; hospital discharge records; hospitalizations; Rotavirus gastroenteritis; rotavirus vaccination; Immunology and Allergy; Immunology; Pharmacology03 medical and health sciencesRotavirus gastroenteriti0302 clinical medicinestomatognathic system030225 pediatricsEnvironmental healthRotavirushospital discharge recordHumansImmunology and AllergyMedicineRotavirus gastroenteritis030212 general & internal medicinehospital discharge recordshospitalizationsSicilyRetrospective StudiesPharmacologycost impact analysiImmunization Programsbusiness.industrySpring seasonInfant NewbornRotavirus VaccinesInfantrotavirus vaccinationLate winterHealth Care CostshumanitiesChild PreschoolVaccination coverageFemalecost impact analysisbusinessResearch PaperhospitalizationHuman Vaccines &amp; Immunotherapeutics
researchProduct

Can bayesian models play a role in dental caries epidemiology? Evidence from an application to the BELCAP data set

2012

Objectives The aim of this study was to show the potential of Bayesian analysis in statistical modelling of dental caries data. Because of the bounded nature of the dmft (DMFT) index, zero-inflated binomial (ZIB) and beta-binomial (ZIBB) models were considered. The effects of incorporating prior information available about the parameters of models were also shown. Methods The data set used in this study was the Belo Horizonte Caries Prevention (BELCAP) study (Bohning et al. (1999)), consisting of five variables collected among 797 Brazilian school children designed to evaluate four programmes for reducing caries. Only the eight primary molar teeth were considered in the data set. A data aug…

Malebounded dataBest fittingBayesian probabilityDeviance (statistics)informative priorDental CariesSettore MED/42 - Igiene Generale E ApplicataSettore MED/01 - Statistica MedicaOverdispersionPrior probabilityStatisticsHumansMedicineChildGeneral DentistryBayesian analysidmftDMF Indexbusiness.industryBelo Horizonte Caries Preventionzero-inflated betabinomialCaries epidemiologyPublic Health Environmental and Occupational HealthBayes TheoremStatistical modelRegressionzero-inflated binomialFemalebusinessAlgorithmsBrazilBayesian analysis; Belo Horizonte Caries Prevention; bounded data; dmft; informative prior; zero-inflated betabinomial; zero-inflated binomialCommunity Dentistry and Oral Epidemiology
researchProduct

The effects of low doses of pregabalin on morphine analgesia in advanced cancer patients

2012

Abstract OBJECTIVES: The aim of this study was to evaluate the opioid response in patients receiving morphine and pregabalin, independently from the presumed pain mechanisms, in comparison with patients receiving morphine treatment only. METHODS: A multicenter prospective randomized controlled study was carried out in a sample of 70 advanced cancer patients with pain requiring strong opioids. Thirty-five patients (group MO) were randomized to receive sustained-release morphine using initial doses of 60 mg/day. Thirty-five patients (group MO-PR) were randomized to start the same morphine doses and pregabalin in increasing doses, starting with 25 mg/day up to 150 mg/day in one week. The follo…

Malecancer painAnalgesicPregabalinPregabalinPainSettore MED/42 - Igiene Generale E Applicatalaw.inventionDose-Response Relationshipadvanced cancer patientDrug TherapyQuality of lifeRandomized controlled triallawassessment toolsNeoplasmsmedicineHumansDrug Interactionslow doses pregabalinBrief Pain Inventorygamma-Aminobutyric AcidPain Measurementneuropathic painAnalgesicsDose-Response Relationship DrugMorphinebusiness.industryassessment tools; cancer pain; neuropathic pain; opioid response; Analgesics; Dose-Response Relationship Drug; Drug Interactions; Drug Therapy Combination; Female; Humans; Italy; Male; Morphine; Neoplasms; Pain; Pain Measurement; Palliative Care; Pregabalin; Treatment Outcome; gamma-Aminobutyric Acid; Anesthesiology and Pain Medicine; Neurology (clinical)Palliative CareAdvanced cancerTreatment OutcomeAnesthesiology and Pain MedicineItalyOpioidlow doses pregabalin; advanced cancer patients; epidemiologic studyopioid responseAnesthesiaCombinationepidemiologic studyMorphineDrug Therapy CombinationFemaleNeurology (clinical)Drugbusinessmedicine.drug
researchProduct