Search results for " induction"

showing 10 items of 526 documents

Highly-parallelized simulation of a pixelated LArTPC on a GPU

2023

The rapid development of general-purpose computing on graphics processing units (GPGPU) is allowing the implementation of highly-parallelized Monte Carlo simulation chains for particle physics experiments. This technique is particularly suitable for the simulation of a pixelated charge readout for time projection chambers, given the large number of channels that this technology employs. Here we present the first implementation of a full microphysical simulator of a liquid argon time projection chamber (LArTPC) equipped with light readout and pixelated charge readout, developed for the DUNE Near Detector. The software is implemented with an end-to-end set of GPU-optimized algorithms. The alg…

multiplication and inductionpulse formationscintillationtutkimuslaitteethiukkasfysiikkaelectric fieldsnoble liquid detectorscharge transportdetector modelling and simulations IIsimulation methods and programsMonte Carlo -menetelmätilmaisimetelectron emissiondouble-phaseprosessointiionizationalgoritmittime projection chamberssimulointiTPC
researchProduct

Adalimumab in active ulcerative colitis: A “real-life” observational study

2013

Abstract Background and aims The effectiveness of adalimumab in the treatment of ulcerative colitis is under debate. Although controlled trials have shown that adalimumab is significantly better than placebo, the absolute clinical benefit is modest. We report data on the effectiveness of adalimumab in a cohort of ulcerative colitis patients treated in 22 Italian centres. Methods All patients with active disease treated with adalimumab were retrospectively reviewed. Co-primary endpoints were clinical remission at weeks 4, 12, 24 and 54. Secondary endpoints were sustained clinical remission, steroid discontinuation, endoscopic remission and need for colectomy. Results Eighty-eight patients we…

musculoskeletal diseasesAdultMaleAdalimumab “Real-life” study Ulcerative colitismedicine.medical_specialtymedicine.medical_treatmentIBDAnti-Inflammatory AgentsAdalimumab; “Real-life” study; Ulcerative colitisAntibodies Monoclonal HumanizedPlaceboCohort StudiesYoung AdultRefractoryAdrenal Cortex HormonesInternal medicineAdalimumabmedicineHumansskin and connective tissue diseases“Real-life” studyRetrospective StudiesColectomySettore MED/12 - GastroenterologiaHepatologybusiness.industryRemission InductionSettore MED/09 - MEDICINA INTERNAGastroenterologyAdalimumabmedicine.diseaseUlcerative colitishumanitiesInfliximabSurgeryDiscontinuationTreatment OutcomeUlcerative colitisCohortColitis UlcerativeDrug Therapy CombinationFemalebusinessmedicine.drug
researchProduct

Early Treatment of Systemic Juvenile Idiopathic Arthritis with Canakinumab and Complete Remission After 2 Years of Treatment Suspension: Case Report …

2019

Systemic juvenile idiopathic arthritis (sJIA) is an autoinflammatory disease characterised by fever and arthritis. We describe the case of a 14-year-old girl hospitalised with fever associated with rash, myalgia, arthralgia and polyarticular involvement. Examinations revealed increased levels of C-reactive protein, erythrocyte sedimentation rate, ferritin, triglycerides, leukocytes, neutrophils, lactate dehydrogenase, fibrinogen, aspartate aminotransferase (AST), alanine aminotransferase (ALT) and γ-glutamyl transferase (GGT). Bone marrow biopsy showed polyclonal leukocyte activation. A genetic study revealed a heterozygous mutation of the MEFV gene, c.442G>C (E148Q), which is typical of…

myalgiaAbdominal painmedicine.medical_specialtyTime FactorsAdolescentCanakinumabFamilial Mediterranean feverArthritisCase Report030204 cardiovascular system & hematologyAntibodies Monoclonal Humanized030226 pharmacology & pharmacyGastroenterology03 medical and health sciences0302 clinical medicineautoinflammatory diseaseInternal medicinemedicineHumansPharmacology (medical)medicine.diagnostic_testbusiness.industryRemission InductionAntibodies MonoclonalGeneral MedicineExanthemamedicine.diseaseMEFVRashdigestive system diseasesArthritis JuvenileCanakinumabTreatment OutcomeErythrocyte sedimentation rateSystemic juvenile idiopathic arthritiFemalemedicine.symptombusinessmedicine.drug
researchProduct

Pedagogical leadership to support new teachers' growth

2016

This study aims to discover the impact of pedagogical leadership on new teachers’ growth. The research is focused on three questions: 1) Are new teachers’ feelings and challenges being understood?; 2) How do new teachers receive support from principals and the school community?; and 3) How does pedagogical leadership impact new teachers’ growth? The research uses the qualitative approach of case studies. Four Finnish schools were selected as participants. The principals of each school and their five new teachers, with less than three years of experience, participated in the interviews. Teachers in Finland have common challenges when they first enter the profession. Finnish school communitie…

new teacherinservice teacher educationtukeminenammatillinen kehitysbasic educationpedagogical leadershipprofessional growthpedagoginen johtaminenFinnish teacheropettajatopettajankoulutusteacher induction
researchProduct

Do newborn infants sense the beat?

2009

newbornsRhythmbeat induction
researchProduct

The modelling of the behaviour of solid inclusions in the EM induced recirculated turbulent flows of liquid metal

2014

Promocijas darbā skaitliski un eksperimentāli pētītas noslēgtas elektromagnētiski ierosinātas šķidrā metāla turbulentās plūsmas ar cietām daļiņām. Šādas plūsmas veidojas metalurģiskajās indukcijas krāsnīs. Darbā ir izveidots uz LES plūsmas aprēķina pieejas bāzēts Lagranža modelis ar paplašinātu spēku kopu inerciālo daļiņu pārneses aprakstam. Veikts eksperimentāls daļiņu koncentrācijas pētījums kvazi-stacionārā stāvoklī, izmantojot jaunu ideju: ferromagnētiskās daļiņas izmantotas kā nevadošu daļiņu fiziskais modelis šķidrajā metālā - tas ir pirmais zināmais eksperimentālais darbs cietu ieslēgumu sadalījuma analīzē elektormagnētiski ierosinātu šķidro metālu plūsmu iekšienē. Eksperiments pierā…

particlesliquid metalPhysicsdaļiņasLESturbulenceFizikašķidrais metālselectromagnetic inductionelektromagnētiskā indukcijaMechanics of Fluids and Gases
researchProduct

The effect of a temperature-sensitive prophage on the evolution of virulence in an opportunistic bacterial pathogen.

2022

https://doi.org/10.1111/mec.16638 Abstract Viruses are key actors of ecosystems and have major impacts on global biogeochemical cycles. Prophages deserve particular attention as they are ubiquitous in bacterial genomes and can enter a lytic cycle when triggered by environmental conditions. We explored how temperature affects the interactions between prophages and other biological levels by using an opportunistic pathogen, the bacterium Serratia marcescens, that harbours several prophages and that had undergone an evolution experiment under several temperature regimes. We found that the release of one of the prophages was temperature-sensitive and malleable to evolutionary changes. We furthe…

prophage inductionMARINE VIRUSESbiologiset vaikutuksetviruksetProphagesvirusLIPOPOLYSACCHARIDESEQUENCEbakteriofagitGeneticsBacteriophagesexperimental evolutionPHYSIOLOGYEcology Evolution Behavior and SystematicsEcosystem11832 Microbiology and virologySERRATIA-MARCESCENSepigeneticsVirulenceINDUCTIONopportunistic pathogenTemperatureLYSOGENYekosysteemit (ekologia)taudinaiheuttajatMUTANTSepigenetiikkalämpötilaBACTERIOPHAGERESISTANCEGenome BacterialMolecular ecologyREFERENCES
researchProduct

Apoptotic induction on HeLa tumor cell line. A comparison of activity between pyrazolo[1,2-a]benzo[1,2,3,4]tetrazinone derivatives and their syntheti…

2009

pyrazolo[12-a]benzo[1234]tetrazinone derivativeApoptotic inductionSettore CHIM/08 - Chimica Farmaceutica
researchProduct

Active disturbance rejection control of linear induction motor

2017

This paper proposes the theoretical framework and the experimental application of the active disturbance rejection control to linear induction motors. Such a nonlinear control (ADRC) technique can be viewed as a particular kind of input-output linearization control, where the nonlinear transformation of the state is not computed by means of the model, but it is estimated online. Such an approach permits to cope with unmodelling dynamics, as well as uncertainty in the knowledge of the model parameters and exogenous disturbances. The effectiveness of the proposed ADRC control law has been verified both by numerical simulations and experimentally on a suitably developed test setup. Moreover, t…

rejection of disturbanceEngineering0209 industrial biotechnologyExtended state observer (ESO)rejection of disturbancesComputer scienceLinear induction motor02 engineering and technologyNonlinear controlInductorActive disturbance rejection controlIndustrial and Manufacturing Engineeringextended state observer020901 industrial engineering & automationSettore ING-INF/04 - AutomaticaControl theoryLinearizationstate feedback control0202 electrical engineering electronic engineering information engineeringlinear induction motor (LIM)Feedback linearizationElectrical and Electronic EngineeringTest setupbusiness.industry020208 electrical & electronic engineeringControl engineeringTransformation (function)Control and Systems EngineeringLinear induction motorA priori and a posterioriState (computer science)Robust controlbusinessNonlinear transformationInduction motor
researchProduct

Good clinical response, remission, and predictors of remission in rheumatoid arthritis patients treated with tumor necrosis factor-α blockers: The GI…

2007

OBJECTIVE: To assess the prevalence of good clinical response and remission in rheumatoid arthritis (RA) patients with longstanding disease treated with anti-tumor necrosis factor-alpha (TNF-alpha) drugs at outpatient clinics. METHODS: Retrospective national study of 14 academic tertiary referral rheumatology medical centers. RA patients with a Disease Activity Score (DAS28) > 3.2 were defined as having active disease and could start TNF-alpha blockers. All patients received one TNF-alpha blocker plus methotrexate (10-20 mg/wk). At the third month the patients were categorized as responders or nonresponders, based on improvement of at least 0.25 of the Health Assessment Questionnaire (HAQ).…

rheumatoid arthritisAdultMaleQuality Assurance Health Carepredictors of remissionTumor Necrosis Factor blockersAntibodies Monoclonal HumanizedSeverity of Illness IndexReceptors Tumor Necrosis FactorEtanerceptArthritis RheumatoidRheumatoid arthritis; Good clinical response; Tumor Necrosis Factor blockersPredictive Value of TestsHumansRheumatoid arthritispredictors of remission; rheumatoid arthritis; tumor necrosis factor-alpha blockersAgedRetrospective StudiesGood clinical responseTumor Necrosis Factor-alphatumor necrosis factor-alpha blockersRemission InductionAdalimumabAntibodies MonoclonalMiddle AgedPrognosisInfliximabLogistic ModelsMethotrexateTreatment Outcomedisability score; good clinical response; remission; rheumatoid arthritis; tumor necrosis factor-α blockersItalyAntirheumatic AgentsImmunoglobulin GFemale
researchProduct