Search results for " intellectual"

Johann Heinrich Pestalozzi nell’attuale panorama della scuola multiculturale.

2017

Il contributo presenta una riflessione sulla scuola attraverso il contributo pedagogico dello zurighese Johann Heinrich Pestalozzi. Partendo dalla sua idea degli “stati dell'umanità”, viene analizzata la situazione dell'educazione nella scuola italiana, sempre più multiculturale. Inoltre, si terrà conto dei metodi di didattica interculturale più appropriati, considerando le inclinazioni e la storia di ciascun alunno e al fine di accompagnare ciascuno nella realizzazione delle proprie potenzialità, per vivere in futuro da protagonista in un mondo che cambia velocemente. The paper presents a reflection on the current Italian educational system, starting from the conceptual legacy of the Swiss…

On the Returns to Invention within Firms: Evidence from Finland

2018

International audience; In this paper we merge individual income data, firm-level data, patenting data, and IQ data in Finland over the period 1988–2012 to analyze the returns to invention for inventors and their coworkers or stakeholders within the same firm. We find that: (i) inventors collect only 8 percent of the total private return from invention; (ii) entrepreneurs get over 44 percent of the total gains; (iii) bluecollar workers get about 26 percent of the gains and the rest goes to white-collar workers. Moreover, entrepreneurs start with significant negative returns prior to the patent application, but their returns subsequently become highly positive.

Ewolucja ludzkości według Hoene-Wrońskiego

2017

The aim of this article is to recall and, at the same time, to update, the theory of the evolution of humanity by Josef Hoëné-Wronski. I am trying to show that the author of Metapolitics (Métapolitique messianique) and of other philosophical and mathematical works was much ahead of his contemporaries concerning his ideas about evolution and these ideas, although expressed in a somewhat archaic and obscure language, are still valid for us today. Hoëné-Wronski has boldly challenged the deterministic picture of the world emerging from modern science and has derived human evolution from the moral and rational development of human beings. He divided it into seven stages. My interpretation of Hoë…

Knowledge as a fictitious commodity: a Polanyian reading of the 'digital economy'

2020

Since the 2008 financial crisis, the attempts to use Karl Polanyi's framework to make sense of current developments have multiplied, producing a noticeable and lively debate. This debate centres on the notion of double movement put forward by the Hungarian thinker in his masterpiece – The Great Transformation. The paper is a contribution to this debate. The first part addresses a series of questions that make the interpretations of the double movement advanced so far not very compelling. To this end, a close reading of Polanyi's text, with the aim of dismantling and rearticulating its analytical structure, is carried out. The upshot is a dynamic and multistage picture of the double process …

Polanyi's double movement and the making of the ‘knowledge economy'

2019

In this chapter, we want to re-evaluate the heuristic role of Polanyi’s double movement by suggesting an alternative reading that could answer several criticisms that have been levelled against it. Moreover, we believe that this reading can give us greater insight into both the nature of the current crisis and its failure to unravel the neoliberal consensus.1 According to our reading, since the Speenhamland measures introduced in 1795 in Britain, faulty welfarist solutions have had the ability to undermine the political force of countermovements calling for protective measures while helping pro-market coalitions to periodically regenerate themselves. For us, this means that the future resol…

Orientālistika (Latvijas Universitātes Raksti, 803. sēj.)

2015

New Insights into Potocki-Shaffer Syndrome: Report of Two Novel Cases and Literature Review

2020

Potocki-Shaffer syndrome (PSS) is a rare non-recurrent contiguous gene deletion syndrome involving chromosome 11p11.2. Current literature implies a minimal region with haploinsufficiency of three genes, ALX4 (parietal foramina), EXT2 (multiple exostoses), and PHF21A (craniofacial anomalies, and intellectual disability). The rest of the PSS phenotype is still not associated with a specific gene. We report a systematic review of the literature and included two novel cases. Because deletions are highly variable in size, we defined three groups of patients considering the PSS-genes involved. We found 23 full PSS cases (ALX4, EXT2, and PHF21A), 14 cases with EXT2-ALX4, and three with PHF21A only…

High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies

2017

Item does not contain fulltext Developmental and epileptic encephalopathy (DEE) is a group of conditions characterized by the co-occurrence of epilepsy and intellectual disability (ID), typically with developmental plateauing or regression associated with frequent epileptiform activity. The cause of DEE remains unknown in the majority of cases. We performed whole-genome sequencing (WGS) in 197 individuals with unexplained DEE and pharmaco-resistant seizures and in their unaffected parents. We focused our attention on de novo mutations (DNMs) and identified candidate genes containing such variants. We sought to identify additional subjects with DNMs in these genes by performing targeted sequ…

Towards text simplification for poor readers with intellectual disability: When do connectives enhance text cohesion?

2013

Abstract Cohesive elements of texts such as connectives (e.g., but, in contrast) are expected to facilitate inferential comprehension in poor readers. Two experiments tested this prediction in poor readers with intellectual disability (ID) by: (a) comparing literal and inferential text comprehension of texts with and without connectives and/or high frequency content words (Experiment 1) and (b) exploring the effects of type and familiarity of connectives on two-clause text comprehension by means of a cloze task (Experiment 2). Neither the addition of high frequency content words nor connectives in general produced inferential comprehension improvements. However, although readers with ID wer…

Association of a functional deficit of the BKCa channel, a synaptic regulator of neuronal excitability, with autism and mental retardation

2006

International audience; Objective: Autism is a complex, largely genetic psychiatric disorder. In the majority of cases, the cause of autism is not known, but there is strong evidence for a genetic etiology. To identify candidate genes, the physical mapping of balanced chromosomal aberrations is a powerful strategy, since several genes have been characterized in numerous disorders. In this study, the authors analyzed a balanced reciprocal translocation arising de novo in a subject with autism and mental retardation. Method: The authors performed the physical mapping of the balanced 9q23/ 10q22 translocation by fluorescent in situ hybridization experiments using bacterial artificial chromosom…