Search results for " iva"

showing 10 items of 60 documents

Inhalable nano into micro dry powders for ivacaftor delivery: The role of mannitol and cysteamine as mucus-active agents.

2020

In this paper the innovative approach of Nano into micro (NiM9 was developed to produce Nanoparticles loaded Ivacaftor to incorporate into mannitol or mannitol/cysteamine micromatrices for drug pulmonary administration in CF. Nanoparticles composed by a mixture of two polyhydrohydroxyethtylaspartamide copolymers containing a loading of Ivacaftor of 15.5 % w/w were produced. These Nanoparticles were incorporated into microparticles to obtain NiM that were characterized in terms of size and size distribution, interaction with CF-AM by rheological and turbidimetric studies as well as by aerodynamic diameter measurements. Finally the activity of Ivacaftor into these NiM was evaluated by in vitr…

Cystic Fibrosisαβ-poly-(N-2-hydroxyethyl)-DL-aspartamide (PHEA) copolymer PHEA ivacaftor mucus-penetrating nanoparticle cell penetrating peptide nano into micro strategy. CysteamineDrug CompoundingPharmaceutical ScienceNanoparticleCystic Fibrosis Transmembrane Conductance Regulator02 engineering and technologyQuinolonesAminophenols030226 pharmacology & pharmacyIvacaftor03 medical and health scienceschemistry.chemical_compound0302 clinical medicineNano-Administration InhalationMucus-penetrating nanoparticlemedicineCopolymerAnimalsMannitolChloride Channel AgonistsCells CulturedExpectorantsCell penetrating peptideNano into micro strategyChemistry021001 nanoscience & nanotechnologyMucusRats Inbred F344IvacaftorCopolymer PHEADrug LiberationSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoMutationNanoparticlesCysteamineMannitolPowders0210 nano-technologyPeptidesαβ-poly-(N-2-hydroxyethyl)-DL-aspartamide (PHEA)medicine.drugNuclear chemistryInternational journal of pharmaceutics
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LA DICHIARAZIONE INFEDELE

2011

IL CONTRIBUTO HA PER OGGETTO IL COMMENTO ALL'ART.5 DEL D.LGS.N.471/1997, NELLA PARTE IN CUI DISCIPLINA LA SANZIONE IRROGABILE PER L'INFEDELTA' DELLA DICHIARAZIONE ANNUALE AI FINI DELL'IVA

DICHIARAZIONE INFEDELE IVASettore IUS/12 - Diritto Tributario
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De l'utilité d'une enquête à court terme ?

1997

This contribution focuses on the pertinence of a short-time survey about professional situations of young trainees in a region, the "decentralized survey. It is analyzed throughout two approaches : the comparison between two surveys, a postal one, carried out seven months after leaving school and a phone survey realized four years after ; the predictive side of the beginning of working life.

EfficacitéEnquête IVA[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationFrance[SHS.ECO] Humanities and Social Sciences/Economics and Finance[SHS.ECO]Humanities and Social Sciences/Economics and Finance
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A la sortie du lycée ... évolution sur trois ans

1988

Enquête IVADevenir professionnel[SHS.EDU]Humanities and Social Sciences/EducationEmploi des jeunes[SHS.EDU] Humanities and Social Sciences/EducationEnseignement secondaireJeuneChômage des jeunesFranceMarché du travail des jeunesInsertion professionnelle des jeunesPassage à la vie activeEnseignement technique long
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Insertion des jeunes en 1985 : premiers résultats

1985

Enquête IVAEmploi des jeunesInsertion des jeunes[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationJeune sans qualificationChômage des jeunesFranceInsertion professionnelle des jeunes
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L'entrée des jeunes dans la vie active en Bourgogne

1986

Enquête IVAEmploi des jeunes[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationBourgogneChômage des jeunesFranceMarché du travail des jeunesInsertion professionnelle des jeunesPassage à la vie active
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L'entrée des jeunes dans la vie active en Bourgogne

1993

International audience

Enquête IVAEmploi des jeunes[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationBourgogneChômage des jeunesFranceMarché du travail des jeunesInsertion professionnelle des jeunesPassage à la vie activeComputingMilieux_MISCELLANEOUS
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De la formation à l'emploi : une transition difficile

2013

En Bourgogne, près de 8 900 jeunes ont quitté le lycée ou l'apprentissage en juin 2011. Sept mois plus tard, 58 pour cent des garçons et 48 pour cent des filles ont trouvé un emploi non aidé. Les effets de la crise économique perdurent avec le tiers des jeunes au chômage. A l'issue d'un contrat d'apprentissage, les garçons connaissent des situations professionnelles plus favorables que les sortants de l'an passé. A contrario, Les filles titulaires d'un CAP rencontrent des débuts difficiles qu'elles sortent du lycée ou de l'apprentissage. Dans un contexte marqué par la récession économique et la réforme de la voie professionnelle, la hiérarchie des diplômes n'est pas remise en cause. Un nive…

Enquête IVAEnquête IPA[SHS.EDU] Humanities and Social Sciences/EducationAnalyse statistiqueInsertion professionnelle des jeunesRelation formation-emploi
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L'enquête Insertion dans la Vie Active, regards croisés national et régional

2002

After a conceptual presentation of the decentralized Integration survey (IVA), the main transformations of this scheme are outlined in a changing economic, social and technological context. Above all, the authors analyse the appropriation of data and the main actors' involvement according to institutional logics at the national and regional levels.

Enquête IVAEnquête IPA[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationFrance
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Beaucoup d'emplois instables à la sortie de l'école

1991

National audience

Enquête IVA[SHS.EDU]Humanities and Social Sciences/EducationEmploi des jeunes[SHS.EDU] Humanities and Social Sciences/EducationChômage des jeunesInsertion professionnelle des jeunesPrécaritéComputingMilieux_MISCELLANEOUS
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