Search results for " jun"

Applications and non-idealities of submicron Al–AlOx–Nb tunnel junctions

2016

We have developed a technique to fabricate sub-micron, 0.6µm×0.6µm Al-AlOx-Nb tunnel junctions using a standard e-beam resist, angle evaporation and double oxidation of the tunneling barrier, resulting in high quality niobium, as determined by the the high measured values of the critical temperature TC ∼ 7.5 K and the gap ∆ ∼ 1.3 meV. The devices show great promise for local nanoscale thermometry in the temperature range 1 - 7.5 K. Electrical characterization of the junctions was performed at sub-Kelvin temperatures both with and without an external magnetic field, which was used to suppress superconductivity in Al and thus bring the junction into a normal-metal-insulator-superconductor (NI…

Co-culture of rat brain cells as a tool for studying cell-cell interactions

2012

Brain capillary endothelial cells (BCECs) form the blood-brain barrier (BBB) in response to interaction with other brain cells (astrocytes, pericytes and neurons). BCECs are characterized by tight junctions (TJ), maturation and stabilization of which require different proteins, such as occludin. When co-cultured with astrocytes and neurons, BCECs were found to form a monolayer resembling the natural BBB: paracellular flux of dopamine and sucrose (i.e. compounds which are unable to cross the BBB in vivo) significantly decreased (1), while the transendothelial electrical resistance (TEER) increased. In these conditions, BCECs produced a larger amount of occludin and tended to localize it at t…

Variants of human CLDN9 cause mild to profound hearing loss

2021

Hereditary deafness is clinically and genetically heterogeneous. We investigated deafness segregating as a recessive trait in two families. Audiological examinations revealed an asymmetric mild to profound hearing loss with childhood or adolescent onset. Exome sequencing of probands identified a homozygous c.475G>A;p.(Glu159Lys) variant of CLDN9 (NM_020982.4) in one family and a homozygous c.370_372dupATC;p.(Ile124dup) CLDN9 variant in an affected individual of a second family. Claudin 9 (CLDN9) is an integral membrane protein and constituent of epithelial bicellular tight junctions that form semi-permeable, paracellular barriers between inner ear perilymphatic and endolymphatic compartment…

Development of an inductive NIS thermometer

2012

Normal metal-Insulator-Superconductor (NIS) tunnel junction thermometers have been under heavy research since 1976 after Rowell and Tsui first presented thanks to their excellent sensitivity to the temperature change in millikelvin regime. In this work, we have designed and studied an inductive readout for NIS tunnel junctions by using on-chip planar inductors and a DC SQUID (Superconducting Quantum Interference Device) to develop a sensitive and fast thermometer for studies of nanoscale heat conduction and bolometry. In this thesis, the processing of the samples fabricated in Nanoscience Center in Jyväskylä are presented, and several processing challenges have been dealt with and the fabri…

Bias and temperature dependence analysis of the tunneling current of normal metal-insulator-normal metal tunnel junctions

2003

Reducing 1/f noise in Al-AlOx-Al tunnel junctions by thermal annealing

2009

Early diagnosis of ureteropelvic junction obstruction in a solitary kidney: when to correctly perform pyeloplasty.

2009

Tendon length estimates are influenced by tracking location

2022

Abstract Purpose Measurement of medial gastrocnemius (MG) tendon length using ultrasonography (US) requires the muscle–tendon junction (MTJ) to be located. Previously, the MG MTJ has been tracked from different proximo-distal locations near the MTJ, which could influence estimates of tendon length change due to the different characteristics of the aponeurosis and tendon. We used US to evaluate the effect of tracking point location on MG MTJ displacement during maximal and submaximal (10, 20 and 30% of the non-injured maximal) isometric plantar flexion contractions. Methods Displacement behaviour of MTJ was tracked from (1) the exact MTJ; and (2) from an insertion point of a muscle fascicle …

Viv Groskop: Älä heittäydy junan alle

2020

Kirja-arvostelu teoksesta Viv Groskop: Älä heittäydy junan alle ja muita elämänoppeja venäläisistä klassikoista (suom. Heli Naski, Atena 2019, 299.s) nonPeerReviewed

Arhetipi “Tūkstoš un vienas nakts pasakās” un latviešu tautas pasakās

2019

Bakalaura darba “Arhetipi “Tūkstoš un vienas nakts pasakās” un latviešu tautas pasakās” mērķis ir atrast gan kopīgo, gan atšķirīgo abu tautu pasaku tēlos, veidu, kā arhetipi izpaužas šajās pasakās, kādas ir viņu īpašības un darbības un, kā ar tām šie arhetipi pauž tautas mentalitāti, vērtības un uzskatus. Bakalaura darbs sastāv no četrām nodaļām: Pirmajā nodaļā tiek apskatīts teorētiskais materiāls par “Tūkstoš un vienas nakts pasakām”, to vēsturi un pirmajiem tulkojumiem gan Eiropā, gan Latvijā. Otrajā nodaļā tiek apskatītas latviešu tautas pasakas, to vēsture un “Latviešu tautas brīnumpasakas”. Trešajā nodaļā autore apskatījusi teorētisko materiālu par K. G. Junga arhetipiem un V. Propa a…