Search results for " lactate"
showing 10 items of 79 documents
Titrated hypertonic/hyperoncotic solution for hypotensive fluid resuscitation during uncontrolled hemorrhagic shock in rats.
2002
In volume- or pressure-controlled hemorrhagic shock (HS) a bolus intravenous infusion of hypertonic/hyperoncotic solution (HHS) proved beneficial compared to isotonic crystalloid solutions. During uncontrolled HS in animals, however, HHS by bolus increased blood pressure unpredictably, and increased blood loss and mortality. We hypothesized that a titrated i.v. infusion of HHS, compared to titrated lactated Ringer's solution (LR), for hypotensive fluid resuscitation during uncontrolled HS reduces fluid requirement, does not increase blood loss, and improves survival.We used our three-phased uncontrolled HS outcome model in rats. HS phase I began with blood withdrawal of 3 ml/100g over 15 mi…
Alteration of hypothalamic glucose and lactate sensing in 48h hyperglycemic rats.
2013
International audience; Hypothalamic detection of nutrients is involved in the control of energy metabolism and is altered in metabolic disorders. Although hypothalamic detection of blood lactate lowers hepatic glucose production and food intake, it is unknown whether it also modulates insulin secretion. To address this, a lactate injection via the right carotid artery (cephalad) was performed in Wistar rats. This triggered a transient increase in insulin secretion. Rats made hyperglycemic for 48h exhibited prolonged insulin secretion in response to a glucose injection via the carotid artery, but lactate injection induced two types of responses: half of the HG rats showed no difference comp…
Association of Monocarboxylate Transporter-1 (MCT1) A1470T Polymorphism (rs1049434) with Forward Football Player Status.
2018
AbstractThe aim of this study was to investigate the association between the MCT1 (monocarboxylate transporter 1) A1470T polymorphism and positional roles in a large cohort of professional football players from five different countries. We compared genotype distributions of the MCT1 A1470T polymorphism between football players (n=694) and non-athlete controls (n=781) from Italy, Poland, Lithuania, Ukraine and Malta, and we analyzed the MCT1 genotype distributions with respect to the players’ positions in the field (e. g. forwards, midfielders, defenders and goalkeepers). Genomic DNA was extracted from either buccal epithelium or peripheral blood using a standard protocol. In the pooled coho…
Comparison of blood lactate and perceived exertion responses in two matched time-under-tension protocols.
2019
PurposeThe aim of this study was to compare the concentration of blood lactate [bLa-] and the subjective perception of exertion of trained men in a moderate repetition protocol (MRP) versus a high repetition protocol (HRP) equated for time under tension.MethodsA sample of 40 healthy young men (aged, 23.2 ± 4.0 years; height, 177.3 ± 7.0 cm; BMI, 24.3 ± 2.2) performed two sessions of 8 sets of bicep curls with a one-week recovery interval between the trials. In the HRP protocol, 20 repetitions were performed with a cadence of 2 seconds of eccentric and 1 second of concentric, while in the MRP protocol 10 repetitions were performed with 4 seconds of eccentric and 2 seconds of concentric. Cade…
Comparison of Exclusive Double Poling to Classic Techniques of Cross-country Skiing
2018
Introduction: This study aimed to 1) determine basic physiological demands during a simulated on-snow cross-country skiing (XCS) race when using grip-waxed skis (all classic XCS techniques [CLASSIC]), versus glide-waxed skis for exclusive double poling (DP) and 2) analyze in which track sections DP is different from CLASSIC under controlled gliding conditions in elite junior and senior skiers. Methods: Nineteen male and female elite XC skiers performed 1) two randomized simulated XCS races over 5.3 km using DP or CLASSIC measuring section times, V˙ O2, HR, blood lactate, and RPE; and 2) V˙ O2peak tests using diagonal stride and DP on treadmill. Results: The total group showed no differences…
Effects of work-interval duration and sport specificity on blood lactate concentration, heart rate and perceptual responses during high intensity int…
2018
The aim of this study was to examine the impacts on blood lactate concentration, measured heart rate and assessment of perceived exertion during split sessions of equal relative load, as also their relationship to the specific sport practised. Nineteen regional-level athletes (nine middle and long-distance runners (cyclic group) and ten field-sport team players (acyclic group)) performed four high-intensity interval training (HIIT) sessions with work-interval durations of 10 s, 50 s, 90 s and 130 s. The sessions were carried out at their usual training sites with a separation of at least 48 hours. Blood lactate concentration was measured at rest and 3 min after the completion of each protoc…
Combined creatine and sodium bicarbonate supplementation enhances interval swimming.
2004
This study examined the effect of simultaneous supplementation of creatine and sodium bicarbonate on consecutive maximal swims. Sixteen competitive male and female swimmers completed, in a randomized order, 2 different treatments (placebo and a combination of creatine and sodium bicarbonate) with 30 days of washout period between treatments in a double-blind crossover procedure. Both treatments consisted of placebo or creatine supplementation (20 g per day) in 6 days. In the morning of the seventh day, there was placebo or sodium bicarbonate supplementation (0.3 g per kg body weight) during 2 hours before a warm-up for 2 maximal 100-m freestyle swims that were performed with a passive recov…
Effect of Pool Length on Blood Lactate, Heart Rate, and Velocity in Swimming
2006
Exercise testing in water has been used to follow the progression of conditioning during regular training in swimmers. The present study examined the effects of pool length in eleven male swimmers on a set of 5 x 200-m freestyle swims with increasing speed from submaximal to maximal. Mean velocity of swimming, blood lactate and heart rate were examined in both 25-m and 50-m pools. Turning benefit as a marker for turning skill was measured separately by a underwater video system (speed difference between pre- and post-turning) during short all-out swims. Maximum force during swimming was measured in tethered swimming and explosive strength of leg extensor muscles was evaluated by a counter m…
Six Hundred Meter–Run and Broken 800’s Contribution to Pacing Improvement in Eight Hundred Meter–Athletics
2013
Little is known about the influence of speed endurance workouts on the improvement of pacing strategies in the 800-m running event. This study aims to analyze it, comparing continuous repetitions vs. interval training workouts. Because we hypothesize that pacing is susceptible to expertise, there might be age differences. Nineteen male 800-m runners (age: 21.36 ± 5.26, season best [SB]: 117.14 ± 5.18 seconds) were tested. Athletes were asked to run 1 × 600 m (6r) at 100% (SB) and 2 × 4 (200 m per 30 seconds) per 15 minutes (B8) at 102% (SB), counterbalanced and randomized within 1 week of difference. Pacing strategy (velocity dynamics) was analyzed by means of time differences in 200-m segm…
The cadence and water temperature effect on physiological responses during water cycling
2013
The aim of the study was to compare the maximal physiological responses during three protocols: maximal test on land cycle ergometer, maximal test on water cycling in an indoor pool at 27 °C (WC27) and at 31 °C (WC31). Moreover, the submaximal physiological responses were compared according cycling cadences and water temperatures during the water protocols. Ten young men were included and performed the protocols in separate days. Blood lactate (BL) concentration, heart rate (HR), oxygen uptake (VO2), ventilation (VE) and thermal comfort (TC) were collected during the exercise. The maximal HR and VO2 showed no significant differences between the protocols: HRmax: 189 ± 7 (Land), 188 ± 14 (WC…