Search results for " light"
showing 10 items of 1141 documents
Visual Performance after AcrySof ReSTOR Aspheric Intraocular Lens Implantation
2008
Purpose: To evaluate distance, intermediate and near visual performance in patients who had undergone implantation of the multifocal aspheric AcrySof ReSTOR intraocular lens (IOL). Methods: Binocular best distance corrected visual acuity (BCVA) at high and low contrast [4 m], best distance corrected near visual acuity (BCNVA) [40 cm], intermediate visual acuity [80 and 60 cm], and distance contrast sensitivity (CS) under photopic [85 cd/m2] and mesopic [3 cd/m2] conditions, were measured in 36 eyes that underwent implantation of the AcrySof ReSTOR Aspheric IOL (SN6AD3). Results: At the 3-month postoperative visit, binocular BCVA was -0.058±0.091, 0.200±0.079, and 0.258±0.071 logMAR, for 100…
Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee.
2018
OBJECTIVE To determine the current state of knowledge and provide evidence-based recommendations that could be valid for all specialists taking care of female pattern hair loss (FPHL), a common form of hair loss in women that is characterized by the reduction of hair density in the central area of the scalp, whereas the frontal hairline is generally well conserved. PARTICIPANTS An expert task force appointed by the Androgen Excess and PCOS Society, which included specialists from dermatology, endocrinology, and reproductive endocrinology. DESIGN Levels of evidence were assessed and graded from A to D. Peer-reviewed studies evaluating FPHL published through December 2017 were reviewed. Crite…
Commissioning and quality assurance procedures for the HDR Valencia skin applicators
2016
The Valencia applicators (Nucletron, an Elekta company, Elekta AB, Stockholm, Sweden) are cup-shaped tungsten applicators with a flattening filter used to collimate the radiation produced by a high-dose-rate (HDR) 192 Ir source, and provide a homogeneous absorbed dose at a given depth. This beam quality provides a good option for the treatment of skin lesions at shallow depth (3-4 mm). The user must perform commissioning and periodic testing of these applicators to guarantee the proper and safe delivery of the intended absorbed dose, as recommended in the standards in radiation oncology. In this study, based on AAPM and GEC-ESTRO guidelines for brachytherapy units and our experience, a set …
LAight® Therapy Significantly Enhances Treatment Efficacy of 16 Weeks of Topical Clindamycin Solution in Hurley I and II Hidradenitis Suppurativa: Re…
2021
<b><i>Background:</i></b> Hidradenitis suppurativa (HS) is a chronic, inflammatory, burdensome skin disease where medical first-line treatment is still limited to long-term, topical and/or systemic antibiotics. The RELIEVE study aimed at evaluating the efficacy of LAight® therapy – a combination of intense pulsed light and radiofrequency – as an adjunct treatment to first-line therapies in Hurley stage I and II HS. <b><i>Methods:</i></b> The RELIEVE study was performed as a two-period multicenter randomized controlled trial with blinded assessment. For period A from week 0 to week 16, the 88 participating subjects were randomized into either a…
Low-level laser therapy for treatment of neurosensory disorders after orthognathic surgery : a systematic review of randomized clinical trials
2017
Background Low-level laser has been widely used in Dentistry and many studies have focused on its application in oral surgeries. This study was conducted with the aim of searching for scientific evidence concerning the effectiveness of laser to reduce pain or paresthesia related to orthognathic surgery. Material and methods An electronic search was performed in PubMed, Scopus, Science Direct, LILACS, SciELO, CENTRAL, Google Scholar, OpenGrey, and ClinicalTrials.gov, up to November 2016, with no restrictions on language or year of publication. Additionally, a hand search of the reference list of the selected studies was carried out. The PICOS strategy was used to define the eligibility crite…
Combining Deroofing with LAight® Therapy for Long-Term Disease Control of Hurley Stage II Hidradenitis Suppurativa: Case Report
2021
There is an increasing consensus that the treatment of Hidradenitis suppurativa (HS) significantly varies with the degree of inflammation and that treatment according to guidelines is not always successful. Here, we report the case of a 31-year-old male with widespread, highly inflammatory Hurley Stage II HS in multiple locations who failed to respond to any kind of established medical treatment, including biologics. As an alternative approach, Ustekinumab was maintained, and additionally the patient was treated with LAight therapy, a combination of intense pulsed light and radiofrequency. After 10 sessions, deroofing of multiple lesions was performed in a two-step process. After a few week…
A single mutation in the recombinant light chain of tetanus toxin abolishes its proteolytic activity and removes the toxicity seen after reconstituti…
1994
Specific proteolysis by the tetanus toxin light chain of a vesicle-associated membrane protein (VAMP) involved in exocytosis is thought to underlie its intracellular blockade of neurotransmitter release. To substantiate this mechanism, recombinant light chain was expressed as a maltose binding protein-light chain fusion product in Escherichia coli. After purification of affinity chromatography and cleavage with factor Xa, the resultant light chain was isolated and its identity confirmed by Western blotting and N-terminal sequencing. It exhibited activity similar to that of the native light chain in proteolyzing its target in isolated bovine small synaptic vesicles and in hydrolyzing a 62-re…
Investigation on the stability of dispersion of zirconia nanoparticles prepared by microwave- hydrothermal synthesis
2005
Difficulties in reproducing the performances of nanoparticles dispersions are obstructive for the progress of the nanotechnology. A plausible reason for this variability is the lack of the control of the stability as well as the dimensions of the nanoparticles in the dispersions. In this work we report results of investigations on the stability of zirconia nanoparticles in aqueous medium, monitoring nanoparticles sizes by means of Transmission Electron Microscopy (TEM), Dynamic Light Scattering (DLS). Nanocrystalline zirconia powders, prepared by microwave-hydrothermal synthesis, were determined to be 6-8 nm in size by TEM observations. By using DLS technique the as-prepared dispersions wit…
The influence of blue light on the Dionaea muscipula cultivation
2018
Rośliny wykorzystują światło jako źródło energii do fotosyntezy, reagują na jego intensywność, długość fali świetlnej i kierunek światła. Jest ono także swoistym sygnałem środowiskowym. Światło jest odbierane przez fotoreceptory roślin, takie jak: kryptochromy, fototropiny oraz fitochromy, a rośliny generują szeroki zakres specyficznych odpowiedzi fizjologicznych przez te receptory. Do badań wykorzystano dwie hodowle roślinne składające się z dwóch odmian muchołówki amerykańskiej - Dionaea muscipula: Regular form oraz Red green. Jedną z hodowli poddano oddziaływaniu światła niebieskiego, a drugą - kontrolną prowadzono w warunkach oddziaływania światła słonecznego. Prowadzono pomiary morfolo…
Les impacts sanitaires de la lumière artificielle nocturne - Un état des lieux des connaissances et des hypothèses
2008
Face à la lumière artificielle nocturne (LAN - Light At Night - dans la littérature médicale), la recherche clinique n'en est qu'à ses prémices, dans une situation comparable à celle dans laquelle elle se trouvait face à la pollution par le bruit il y a une trentaine d'années. Pour autant, les scientifiques s'intéressent de plus en plus aux impacts que l'éclairage artificiel peut avoir sur la santé humaine par le biais d'un dérèglement des rythmes circadiens (d'environ 24 heures - du latin circa, environ, et dies, jour), cycles biologiques souvent " calés " sur l'alternance naturelle d'un jour et d'une nuit. Pour l'être humain, comme pour la plupart des espèces complexes, cette rythmicité j…