Search results for " light"
showing 10 items of 1141 documents
Optical properties and structure particularities of LiNbO 3 crystals grown from a boron-doped melt
2019
A series of LiNbO3:B crystals was grown from the melt doped by boron. It is shown that LiNbO3:B crystals possess an increased resistance to optical damage. We have found changes according to Raman spectra confirming the ordering of Li+, Nb5+ cations and vacancies along the polar axis. The chemical interactions were studied in the system Li2O–B2O3–Nb2O5. Boron cations are unable to incorporate into a cation sublattice of LiNbO3, but they change the physic-chemical structure of a melt. It contributes to an increased structure and optical uniformity of LiNbO3:B.
Cerebrospinal Fluid Analysis in Multiple Sclerosis Diagnosis: An Update
2019
Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system (CNS) with brain neurodegeneration. MS patients present heterogeneous clinical manifestations in which both genetic and environmental factors are involved. The diagnosis is very complex due to the high heterogeneity of the pathophysiology of the disease. The diagnostic criteria have been modified several times over the years. Basically, they include clinical symptoms, presence of typical lesions detected by magnetic resonance imaging (MRI), and laboratory findings. The analysis of cerebrospinal fluid (CSF) allows an evaluation of inflammatory processes circumscribed to the CNS and reflects chan…
Comparison of high‐speed optical observations of a lightning flash from space and the ground
2020
We analyze a nighttime negative cloud-to-ground lightning flash in Colombia observed from the ground with a high-speed camera at 5,000 images per second and from space by the Atmosphere-Space Interactions Monitor (ASIM) on the International Space Station (ISS), the Lightning Imaging Sensor also on the ISS (ISS-LIS), and the Geostationary Lightning Mapper (GLM) on GOES-16. The space instruments measure the oxygen band at 777.4 nm, allowing for direct comparisons of measurements, and the ground-based camera observes in a wide visible band. After conversion to energy emitted at the cloud top, we find a good linear correspondence of the optical energies measured by the three space instruments, …
Reliable Detection and Smart Deletion of Malassez Counting Chamber Grid in Microscopic White Light Images for Microbiological Applications
2015
AbstractIn biology, hemocytometers such as Malassez slides are widely used and are effective tools for counting cells manually. In a previous work, a robust algorithm was developed for grid extraction in Malassez slide images. This algorithm was evaluated on a set of 135 images and grids were accurately detected in most cases, but there remained failures for the most difficult images. In this work, we present an optimization of this algorithm that allows for 100% grid detection and a 25% improvement in grid positioning accuracy. These improvements make the algorithm fully reliable for grid detection. This optimization also allows complete erasing of the grid without altering the cells, whic…
New Insights Into the Skin Microbial Communities and Skin Aging
2020
Although it is well-known that human skin aging is accompanied by an alteration in the skin microbiota, we know little about how the composition of these changes during the course of aging and the effects of age-related skin microbes on aging. Using 16S ribosomal DNA and internal transcribed spacer ribosomal DNA sequencing to profile the microbiomes of 160 skin samples from two anatomical sites, the cheek and the abdomen, on 80 individuals of varying ages, we developed age-related microbiota profiles for both intrinsic skin aging and photoaging to provide an improved understanding of the age-dependent variation in skin microbial composition. According to the landscape, the microbial composi…
Microscope system with on axis programmable Fourier transform filtering
2017
Abstract We propose an on-axis microscope optical system to implement programmable optical Fourier transform image processing operations, taking advantage of phase and polarization modulation of a liquid crystal on silicon (LCOS) display. We use a Hamamatsu spatial light modulator (SLM), free of flickering, which therefore can be tuned to fully eliminate the zero order component of the encoded diffractive filter. This allows the realization of filtering operation on axis (as opposed to other systems in the literature that require operating off axis), therefore making use of the full space bandwidth provided by the SLM. The system is first demonstrated by implementing different optical proce…
Two-photon light-sheet microscopy for high-speed whole-brain functional imaging of zebrafish neuronal physiology and pathology
2020
We present the development of a custom-made two-photon light-sheet microscope optimized for high-speed (5 Hz) volumetric imaging of zebrafish larval brain for the analysis of neuronal physiological and pathological activity. High-speed volumetric two-photon light-sheet microscopy is challenging to achieve, due to constrains on the signal-to-noise ratio. To maximize this parameter, we optimized our setup for high peak power of excitation light, while finely controlling its polarization, and we implemented remote scanning of the focal plane to record without disturbing the sample. Two-photon illumination is advantageous for zebrafish larva studies since infra-red excitation does not induce a …
Handheld and cost-effective Fourier lightfield microscope
2022
In this work, the design, building, and testing of the most portable, easy-to-build, robust, handheld, and cost-effective Fourier Lightfield Microscope (FLMic) to date is reported. The FLMic is built by means of a surveillance camera lens and additional off-the-shelf optical elements, resulting in a cost-effective FLMic exhibiting all the regular sought features in lightfield microscopy, such as refocusing and gathering 3D information of samples by means of a single-shot approach. The proposed FLMic features reduced dimensions and light weight, which, combined with its low cost, turn the presented FLMic into a strong candidate for in-field application where 3D imaging capabilities are pursu…
Optical-Microwave Sensor for Real-Time Measurement of Water Contamination in Oil Derivatives
2023
This paper presents a novel microwave sensor using optical activation for measuring in real-time the water contamination in crude oil or its derivatives. The sensor is constructed from an end-coupled microstrip resonator that is interconnected to two pairs of identical fractal structures based on Moore curves. Electromagnetic (EM) interaction between the fractal curves is mitigated using a T-shaped microstrip-stub to enhance the performance of the sensor. The gap in one pair of fractal curves is loaded with light dependent resistors (LDR) and the other pair with microwave chip capacitors. The chip capacitors were used to increase the EM coupling between the fractal gaps to realize a high Q-…
Polarization Modulation Instability in All-Normal Dispersion Microstructured Optical Fibers With Quasi-Continuous Pump
2019
We report the experimental observation of the polarization modulation instability (PMI) effect in all-normal dispersion (ANDi) microstructured optical fibers (MOFs) with quasi-continuous pumping. The small unintentional birefringence (~10-5), that any realistic non-polarization maintaining MOF exhibits, contributes to this nonlinear effect. PMI can produce two sidebands whose polarization state is orthogonal to the polarization of the pump. In this work, only one type of PMI process is observed, i.e., when the pump is polarized along the slow axis of the fiber and sidebands are generated in the fast axis mode. This PMI process was studied experimentally in two ANDi fibers with different dis…