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showing 10 items of 1548 documents
The impact of corporate social responsibility initiative on sustainable livelihood capitals of cocoa farmers in Ghana : a case study of cocoa livelih…
2015
The Cocoa Livelihood Programme (CLP), an initiative of corporate organizations in collaboration with the World Cocoa Foundation (WFC) in line with their corporate social responsibility (CSR), was introduced in Ghana by Solidaridad West Africa in the year 2009. This CSR initiative is to promote sustainable livelihoods of cocoa farmers. Qualitative research method of approach was used to examine the impact of the CLP on the livelihoods of participating cocoa farmers in the Ahafo Ano South District using the five capitals of the Sustainable Livelihood (SL) Framework. Two research questions were answered using thematic coding and analysis. The findings show that the cocoa livelihood programme (…
Black lives matter : rakenteellisen rasismin äärellä
2020
Syrjinnänvastaiset protestit ovat nostaneet rasismin historian huomion keskipisteeksi eri puolilla maailmaa. Patsaiden ja muiden kulttuuristen symboleiden sijaan mielenosoituksen perimmäisenä kohteena on laajalle levinnyt rakenteellinen rasismi, joka on keskeinen osa myös suomalaista yhteiskuntaa. nonPeerReviewed
Book review: Student Lives in Crisis : Deepening Inequality in the Times of Austerity
2018
Immunoaffinity purification and characterization of mitochondrial membrane-bound D-3-hydroxybutyrate dehydrogenase from Jaculus orientalis.
2008
Abstract Background The interconversion of two important energy metabolites, 3-hydroxybutyrate and acetoacetate (the major ketone bodies), is catalyzed by D-3-hydroxybutyrate dehydrogenase (BDH1: EC 1.1.1.30), a NAD+-dependent enzyme. The eukaryotic enzyme is bound to the mitochondrial inner membrane and harbors a unique lecithin-dependent activity. Here, we report an advanced purification method of the mammalian BDH applied to the liver enzyme from jerboa (Jaculus orientalis), a hibernating rodent adapted to extreme diet and environmental conditions. Results Purifying BDH from jerboa liver overcomes its low specific activity in mitochondria for further biochemical characterization of the e…
CEUS LI-RADS: a pictorial review
2020
AbstractContrast-enhanced ultrasound (CEUS) greatly improved the diagnostic accuracy of US in the detection and characterization of focal liver lesions (FLLs), and it is suggested and often included in many international guidelines as an important diagnostic tool in the imaging work-up of cirrhotic patients at risk for developing hepatocellular carcinoma (HCC). In particular, CEUS Liver Imaging Reporting and Data System (LI-RADS) provides standardized terminology, interpretation, and reporting for the diagnosis of HCC. The aim of this pictorial essay is to illustrate CEUS features of nodules discovered at US in cirrhotic liver according to LI-RADS categorization.
Article Commentary: Clinical Medicine: Endocrinology and Diabetes: Insulin Resistance–-a Link between Inflammation and Hepatocarcinogenesis?
2009
The incidence of hepatocellular carcinoma (HCC) is increasing world wide. The risk factors for the development of HCC include liver cirrhosis, chronic alcohol intake, and chronic viral hepatitis. These conditions are associated with inflammation, liver cell injury, and oxidative stress. The signaling pathways that contribute to liver cell injury have been shown to also promote insulin resistance in hepatocytes. On the other hand, obesity and diabetes have been suggested as risk factors for the development of chronic liver disease and HCC. The molecular mediators (e.g. stress kinases) and signaling pathways that contribute to cellular injury, proliferation and insulin resistance are also ac…
Analisi di funzionalità delle rotatorie a fiore
2012
Le attività di ricerca inerenti la geometria dei nodi viari, svolte soprattutto in Enti di ricerca europei, in tempi relativamente recenti hanno consentito di ideare nuove tipologie di intersezioni stradali che presentano un indubbio interesse, soprattutto in termini di funzionalità e di sicurezza della circolazione. Tra le soluzioni più interessanti si annoverano gli schemi affini alle tradizionali rotatorie come ad esempio le rotatorie a spirale, le turbo rotatorie e le rotatorie a fiore. Pur trattandosi di soluzioni con circolazione rotatoria, in genere negli schemi di nuova concezione le modalità di regolamentazione dei flussi veicolari risultano assai diverse rispetto a quanto avviene …
Impact of SARS-CoV-2 Pandemic on the Management of Patients with Hepatocellular Carcinoma.
2022
Worldwide, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) significantly increases mortality and morbidity. The Coronavirus Disease 2019 (COVID-19) outbreak has had a considerable impact on healthcare systems all around the world, having a significant effect on planned patient activity and established care pathways, in order to meet the difficult task of the global pandemic. Patients with hepatocellular carcinoma (HCC) are considered a particularly susceptible population and conceivably at increased risk for severe COVID-19 because of two combined risk factors: chronic advanced liver disease and HCC itself. In these challenging times, it is mandatory to reshape clinical pra…
Role of LI-RADS Indeterminate Observations in the Risk of Hepatocellular Carcinoma after HCV Eradication with Direct-Acting Antivirals.
2022
Purpose: To assess whether HCC (LR-5) occurrence may be associated with the presence of Liver Imaging Reporting and Data System (LI-RADS) indeterminate observations in patients with hepatitis C virus infection treated with direct acting antiviral (DAA) therapy. Materials and methods: This retrospective study included patients with HCV-related cirrhosis who achieved sustained virologic response (SVR) after DAA therapy between 2015 and 2019 and submitted to CT/MRI follow-ups with a minimum interval time of six months before and after DAA. Two blinded readers reviewed CT/MRI to categorize observations according to LI-RADS version 2018. Differences in rate of LI-RADS 5 observations (i.e., LR-5)…
Validity and reliability of the Italian version of the Chronic Liver Disease Questionnaire (CLDQ-I) for the assessment of health-related quality of l…
2005
Background.: The Chronic Liver Disease Questionnaire is a specific health-related quality of life assessment designed for patients with liver diseases. Aim.: The aim of this paper is to report on the validity, reliability and sensitivity to change of the Italian version (Chronic Liver Disease Questionnaire-I) in subjects with HCV infection. Subjects.: The Chronic Liver Disease Questionnaire-I was administered to 350 subjects with HCV infection together with the World Health Organization Quality of Life Assessment, abbreviated version, a generic quality of life assessment. Methods.: The instrument was translated from English, backtranslated and reviewed in focus groups in the framework of a …