Search results for " locali"
showing 10 items of 539 documents
Rediscovery of Hieracium nebrodense (Asteraceae), a little-known endemic of Sicily (Italy)
2016
Hieracium nebrodense Tineo ex Lojac., a little-known endemic of Sicily, has been rediscovered from the type locality after almost two centuries since its first and only collection made in 1830 in the Madonie Mountains (N Sicily). In line with the treatment in ‘Med-Checklist 2’, it is reclassified as a subspecies of H. schmidtii. A new combination is made and a detailed description and illustration are provided.
Tetraspan vesicle membrane proteins: Synthesis, subcellular localization, and functional properties
2002
Tetraspan vesicle membrane proteins (TVPs) are characterized by four transmembrane regions and cytoplasmically located end domains. They are ubiquitous and abundant components of vesicles in most, if not all, cells of multicellular organisms. TVP-containing vesicles shuttle between various membranous compartments and are localized in biosynthetic and endocytotic pathways. Based on gene organization and amino acid sequence similarities TVPs can be grouped into three distinct families that are referred to as physins, gyrins, and secretory carrier-associated membrane proteins (SCAMPs). In mammals synaptophysin, synaptoporin, pantophysin, and mitsugumin29 constitute the physins, synaptogyrin 1-…
Multiple Surface Cracking and Debonding Failure for Thin Thermal Coatings
2019
Abstract A mechanical analysis of thin films of quasi-brittle materials used as thermal coatings for superalloy substrate is proposed. The study considers a bi-material element subjected to uniform tension formed by a thin layer of quasi-brittle material (typically a ceramic) bonded on an elastic substrate. The bounding between the coating film and the substrate is realized by a very thin primer which mechanically modeled as a zero thickness cohesive frictional interface. The analysis is developed by a non-linear finite element simulation in which, in order to consider damage size effects, a non-local isotropic damage model is adopted for the quasi-brittle coating. The results of the analys…
Mutational analysis of the RNA-binding domain of the Prunus necrotic ringspot virus (PNRSV) movement protein reveals its requirement for cell-to-cell…
2005
AbstractThe movement protein (MP) of Prunus necrotic ringspot virus (PNRSV) is required for cell-to-cell movement. MP subcellular localization studies using a GFP fusion protein revealed highly punctate structures between neighboring cells, believed to represent plasmodesmata. Deletion of the RNA-binding domain (RBD) of PNRSV MP abolishes the cell-to-cell movement. A mutational analysis on this RBD was performed in order to identify in vivo the features that govern viral transport. Loss of positive charges prevented the cell-to-cell movement even though all mutants showed a similar accumulation level in protoplasts to those observed with the wild-type (wt) MP. Synthetic peptides representin…
Heterogeneity in shore flies – the case ofGlenantheHaliday (Diptera: Ephydridae) in the Old World
2011
Abstract Old World species of the genus Glenanthe are treated comprehensively with an emphasis on the unusually diverse morphological heterogeneity discovered in structures of the male terminalia. As perspective for this treatment, the tribe Lipochaetini, in which Glenanthe is placed, is characterized and discussed, and an annotated key to the four included genera is provided to facilitate their identification. Glenanthe is demonstrated to be a monophyletic lineage within Lipochaetini. Seven Old World species of Glenanthe are now known, including two new Afrotropical species as follows (type locality in parenthesis): G. namibia n. sp. (Namibia. Mukwe: Divuju: Okavango River [18°04’04”S, 21°…
p75NTRin the spleen: Age-dependent changes, effect of NGF and 4-methylcatechol treatment, and structural changes in p75NTR-deficient mice
2003
In addition to their well-known actions within the nervous system, neurotrophins and their receptors are involved in immune system functioning, as demonstrated by their wide distribution in lymphoid tissues and their in vitro actions on immunocompetent cells. Nevertheless, the in vivo roles of neurotrophin-receptor systems in lymphoid tissues, as well as the scope of their influence throughout development and adulthood, are yet to be clarified. In the present study, we used combined morphological and immunohistochemical techniques to investigate the presence and cellular localization of p75NTR, the pan-neurotrophin receptor protein, in rat spleen from newborns to aging individuals, and the …
Post-translational modifications on RNA-binding proteins: accelerators, brakes, or passengers in neurodegeneration?
2021
RNA-binding proteins (RBPs) are critical players in RNA expression and metabolism, thus, the proper regulation of this class of proteins is critical for cellular health. Regulation of RBPs often occurs through post-translational modifications (PTMs), which allow the cell to quickly and efficiently respond to cellular and environmental stimuli. PTMs have recently emerged as important regulators of RBPs implicated in neurodegenerative disorders, in particular amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Here, we summarize how disease-associated PTMs influence the biophysical properties, molecular interactions, subcellular localization, and function of ALS/FTD-linked …
HSP90 and eNOS partially co-localize and change cellular localization in relation to different ECM components in 2D and 3D cultures of adult rat card…
2007
Background information. Cultivation techniques promoting three-dimensional organization of mammalian cells are of increasing interest, since they confer key functionalities of the native ECM (extracellular matrix) with a power for regenerative medicine applications. Since ECM compliance influences a number of cell functions, Matrigel-based gels have become attractive tools, because of the ease with which their mechanical properties can be controlled. In the present study, we took advantage of the chemical and mechanical tunability of commonly used cell culture substrates, and co-cultures to evaluate, on both two- and three-dimensional cultivated adult rat cardiomyocytes, the impact of ECM c…
Scelta varietale nei distretti tradizionali e nuovi areali
2019
Tonda di Giffoni, Tonda Gentile Romana e Tonda Gentile Trilobata: il panorama varietale italiano è piuttosto ristretto e anche le nuove aree in cui il nocciolo è in espansione puntano sulle cultivar tradizionali più apprezzate dall’industria. Ma dopo l’esperienza positiva della Tonda Francescana® alcune isolate iniziative di miglioramento genetico puntano ad ampliare la piattaforma varietale e clonale
Comments on `Nonlocal strain softening bar revisited' by Christer Nilsson: [International Journal of Solids and Structures 34 (1997) 4399-4419]
1999
Nilsson (1997) addressed the analytical solution of an elastic plastic softening bar in extension within the framework of nonlocal plasticity, making use to this purpose of a theory of nonlocal plasticity preliminary devised in the same paper (Section 2). The results there presented - from the thermodynamic arguments supporting the devised theory, to the bar solution - are quite interesting. The writers, involved in the same research area, wish to discuss a few points of the paper in a fully collaborative spirit. We use the same notation as in Nilsson's paper.