Search results for " low"
showing 10 items of 972 documents
Voltammetric Investigation on Uranyl Sorption by Alginate Based Material. Influence of Hydrolysis and pH Dependence
2015
The removal of U(VI) as uranyl (UO22+) from aqueous solutions was investigated by sorption onto alginate based material. The hydrolysis of uranyl ion was always taken into account in the calculations of free (22UO) ion in aqueous solution, in the experimental pH range considered, as well as the acid-base properties of alginate polymer. The sorption process follows a pseudo-second order kinetic model and the sorption rate decreases when the pH value increases. In addition to the classical Langmuir and Freundlich models, the equilibrium data were fitted by using a modified multi-component equilibrium model, never tested before. Differential Pulse Voltammetry (DPV) and Inductively Coupled Plas…
THE 1-HARMONIC FLOW WITH VALUES IN A HYPEROCTANT OF THE N-SPHERE
2014
We prove the existence of solutions to the 1-harmonic flow — that is, the formal gradient flow of the total variation of a vector field with respect to the [math] -distance — from a domain of [math] into a hyperoctant of the [math] -dimensional unit sphere, [math] , under homogeneous Neumann boundary conditions. In particular, we characterize the lower-order term appearing in the Euler–Lagrange formulation in terms of the “geodesic representative” of a BV-director field on its jump set. Such characterization relies on a lower semicontinuity argument which leads to a nontrivial and nonconvex minimization problem: to find a shortest path between two points on [math] with respect to a metric w…
Cascaded Multilevel Inverter-Based Asymmetric Static Synchronous Compensator of Reactive Power
2022
The topology of the static synchronous compensator of reactive power for a low-voltage three-phase utility grid capable of asymmetric reactive power compensation in grid phases has been proposed and analysed. It is implemented using separate, independent cascaded H-bridge multilevel inverters for each phase. Every inverter includes two H-bridge cascades. The first cascade operating at grid frequency is implemented using thyristors, and the second one—operating at high frequency is based on the high-speed MOSFET transistors. The investigation shows that the proposed compensator is able to compensate the reactive power in a low-voltage three-phase grid when phases are loaded by highly asymmet…
New Lipid Modulating Drugs: The Role of Microsomal Transport Protein Inhibitors
2011
Microsomal triglyceride transfer protein (MTP) is involved in the synthesis of very low density lipoprotein in the liver. Its deficiency results in abetalipoproteinemia. MTP inhibitors target the assembly and secretion of apolipoprotein B-containing lipoproteins. These agents may potentially play a role, alone or in combination, in the treatment of hypercholesterolemia or hypertriglyceridemia. Clinical applications of MTP inhibitors initially focused primarily on high-dose monotherapy in order to produce substantial reductions in LDL-cholesterol levels but these proved to induce significant hepatic steatosis and transaminase elevations. However, likely orphan indications for MTP inhibitors,…
On the pathogenesis of atherosclerosis: enzymatic transformation of human low density lipoprotein to an atherogenic moiety.
1995
Combined treatment with trypsin, cholesterol esterase, and neuraminidase transforms LDL, but not HDL or VLDL, to particles with properties akin to those of lipid extracted from atherosclerotic lesions. Single or double enzyme modifications, or treatment with phospholipase C, or simple vortexing are ineffective. Triple enzyme treatment disrupts the ordered and uniform structure of LDL particles, and gives rise to the formation of inhomogeneous lipid droplets 10-200 nm in diameter with a pronounced net negative charge, but lacking significant amounts of oxidized lipid. Enzymatically modified LDL (E-LDL), but not oxidatively modified LDL (ox-LDL), is endowed with potent complement-activating c…
Common genetic variation of the cholesteryl ester transfer protein gene strongly predicts future cardiovascular death in patients with coronary arter…
2003
OBJECTIVES We sought to evaluate the association between cholesteryl ester transfer protein (CETP) genotypes and the risk of future cardiovascular mortality in patients with coronary artery disease (CAD). BACKGROUND Polymorphisms of the CETP gene influence CETP activity and high-density lipoprotein (HDL) cholesterol concentration and might affect the long-term prognosis and response to statin therapy in patients with CAD. METHODS We used serum samples and deoxyribonucleic acid collected at baseline from a prospective cohort of 1,211 patients with CAD prospectively followed up (median follow-up of 4.1 years), 82 of whom experienced a fatal cardiovascular event. The CETP/C-629A and I405V poly…
Enzymatically modified nonoxidized low-density lipoprotein induces interleukin-8 in human endothelial cells: role of free fatty acids.
2002
Background— Treatment of low-density lipoprotein (LDL) with a protease and cholesterolesterase transforms the lipoprotein to an entity that resembles lipoprotein particles in atherosclerotic lesions, which have a high content of free cholesterol, reflecting extensive de-esterification in the intima. Because de-esterification would occur beneath the endothelium, we examined the effects of enzymatically modified LDL (E-LDL) on cultured endothelial cells. Methods and Results— Incubation of endothelial cells with E-LDL provoked selective accumulation of interleukin (IL)-8 mRNA and production of the cytokine. Chemical analyses and depletion experiments indicated that the effect was caused by th…
Periodontal treatment on patients with cardiovascular disease : systematic review and meta-analysis
2018
Podeu consultar la versió en castellà del document a: http://hdl.handle.net/2445/153580
The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study
2020
Funder: Opetus- ja Kulttuuriministeriö; doi: http://dx.doi.org/10.13039/501100003126
Aggregation of fuzzy structures based on equivalence relations
2016
Elektroniskā versija nesatur pielikumus