Search results for " malaria."

Artesunate – An anti-malarial natural product derivative for cancer therapy

2015

Continental-scale patterns of pathogen prevalence: a case study on the corncrake

2014

Pathogen infections can represent a substantial threat to wild populations, especially those already limited in size. To determine how much variation in the pathogens observed among fragmented populations is caused by ecological factors, one needs to examine systems where host genetic diversity is consistent among the populations, thus controlling for any potentially confounding genetic effects. Here, we report geographic variation in haemosporidian infection among European populations of corncrake. This species now occurs in fragmented populations, but there is little genetic structure and equally high levels of genetic diversity among these populations. We observed a longitudinal gradient…

Dimensions de la vulnérabilité liée au paludisme dans deux zones de Madagascar : apports d'une approche mixte

2019

Le risque de décès, d’aggravation d’une maladie ou d’endettement dans ses suites, dépend des dispositifs et moyens disponibles et accessibles à la population pour y faire face. Ainsi, la vulnérabilité liée au paludisme dépend des contextes socio-économique et géoclimatique qui déterminent le risque de transmission, des comportements individuels ou collectifs, et des moyens des ménages pour faire face à la maladie, la prendre en charge ou la prévenir.La présente étude vise à identifier les déterminants de la vulnérabilité liée au paludisme de la population de Madagascar, en analysant le contexte et les comportements de prévention et de recours aux soins médicaux en cas de fièvre. Une étude q…

Chronicles of rice, mosquitoes and malaria in Spain: the case of the province of Valencia (18th-20th centuries)

2010

This study analyzes the situation of the rice fields in the Valencia province (Eastern Spain) during the centuries XVIII-XX. This area, together with the region of Campo Arañuelo (Western Spain), is one of the territories with highest malaria prevalence during the Spain's Modern History. Medical, demographic, social, economic and legal issues related with the problematic of the rice during this epoch are also discussed. Furthermore, this article provides information about the supposed transmission mechanisms of the disease, as well as the fight against it through chemotherapeutic and environmental sanitation techniques.

Data from: Continental-scale patterns of pathogen prevalence: a case study on the corncrake

2014

Pathogen infections can represent a substantial threat to wild populations, especially those already limited in size. To determine how much variation in the pathogens observed among fragmented populations is caused by ecological factors, one needs to examine systems where host genetic diversity is consistent among the populations, thus controlling for any potentially confounding genetic effects. Here, we report geographic variation in haemosporidian infection among European populations of corncrake. This species now occurs in fragmented populations, but there is little genetic structure and equally high levels of genetic diversity among these populations. We observed a longitudinal gradient…

Amphoteric polyamidoamines in the treatment of malaria

2012

The present invention relates to the use of amphoteric polyamidoamines with MW of 10-100 kDa as antimalarial agents or carriers of antimalarial drugs and to formulations thereof.

Data from: Impact of host nutritional status on infection dynamics and parasite virulence in a bird-malaria system

2013

1. Host resources can drive the optimal parasite exploitation strategy by offering a good or a poor environment to pathogens. Hosts living in resource-rich habitats might offer a favourable environment to developing parasites because they provide a wealth of resources. However, hosts living in resource-rich habitats might afford a higher investment into costly immune defences providing an effective barrier against infection. Understanding how parasites can adapt to hosts living in habitats of different quality is a major challenge in the light of the current human-driven environmental changes. 2. We studied the role of nutritional resources as a source of phenotypic variation in host exploi…