Search results for " malattie."
showing 10 items of 1941 documents
Tono e reattività bronchiale nell'anziano
2008
L’iperreattività bronchiale e la BPCO nel paziente anziano
2006
The Attenuation of the Bronchodilatory Effect of Deep Inspiration (DI) in COPD Is Related to Reduced Airway Distensibility as Measured by HRCT
2005
Italian Registry of Haemophilia and Allied Disorders. Objectives, methodology and data analysis
2008
Epidemiology, Physiology and Clinical Approach to Sleepiness at the Wheel in OSA Patients: A Narrative Review
2022
Sleepiness at the wheel (SW) is recognized as an important factor contributing to road traffic accidents, since up to 30 percent of fatal accidents have been attributed to SW. Sleepiness-related motor vehicle accidents may occur both from falling asleep while driving and from behavior impairment attributable to sleepiness. SW can be caused by various sleep disorders but also by behavioral factors such as sleep deprivation, shift work and non-restorative sleep, as well as chronic disease or the treatment with drugs that negatively affect the level of vigilance. An association between obstructive sleep apnea (OSA) and motor vehicle accidents has been found, with an increasing risk in OSA pati…
Network meta-analysis of randomized trials in multiple myeloma: Efficacy and safety in frontline therapy for patients not eligible for transplant
2022
The treatment scenario for newly-diagnosed transplant-ineligible multiple myeloma patients (NEMM) is quickly evolving. Currently, combinations of proteasome inhibitors (PI) and/or immunomodulatory drugs (IMiD) +/- the monoclonal antibody Daratumumab are used for first-line treatment, even if head-to-head comparisons are lacking. To compare efficacy and safety of these regimens, we performed a network meta-analysis (NMA) of 27 phase 2/3 randomized trials including a total of 12935 patients and 23 different schedules. Four efficacy/outcome and one safety indicators were extracted and integrated to obtain (for each treatment) the surface under the cumulative ranking-curve (SUCRA), a metric use…
ABSOLUTE LYMPHOCYTE COUNT AS PREDICTOR FOR SURVIVAL IN NEWLY DIAGNOSED ELDERLY PATIENTS WITH MULTIPLE MYELOMA
2011
ABSOLUTE LYMPHOCYTE COUNT IS NOT A PREDICTOR FOR SURVIVAL IN NEWLY DIAGNOSED ELDERLY PATIENTS WITH MULTIPLE MYELOMA. FINAL RESULTS OF A MULTICENTER S…
2012
Conseguenze metaboliche dell'ipossia
2011
Riassunto La sopravvivenza in condizioni di ipossia dipende dall’attivazione di processi cellulari complessi, con risposte di adattamento (quali il potenziamento del trasporto di O2 attraverso l’aumento dell’eritropoiesi, l’attivazione dell’angiogenesi e l’aumento della glicolisi anaerobica) e l’inibizione di processi metabolici che richiedono alta disponibilità di O2. Ciò consente di mantenere l’omeostasi energetica anche in condizioni di ridotta disponibilità di O2. Nel modello fisiologico del soggiorno ad alta quota si verificano riduzione di peso e della capacità di lavoro associata a riduzione della massa muscolare, che però sono reversibili al ripristino di condizioni di normossia. Le…
Dairy calcium intake and lifestyle risk factors for bone loss in hiv-infected and uninfected mediterranean subjects
2012
Abstract Background Despite the reported high prevalence of osteoporosis in the human immunodeficiency virus (HIV)-population, there have been no previous studies examining dairy calcium intake and bone mineral density (BMD) in HIV-subjects. We assessed the prevalence of low BMD in HIV-infected and uninfected subjects and analyzed the effects of calcium intake, lifestyle and HIV-related risk factors on BMD. Methods One hundred and twelve HIV-infected subjects were consecutively enrolled. Seventy- six HIV-uninfected subjects matched for age and sex were enrolled as the control group. The HIV-subjects were interviewed about lifestyle habits and completed a weekly food-frequency questionnaire …