Search results for " memory"
showing 10 items of 1351 documents
Cannabis use in male and female first episode of non-affective psychosis patients: long-term clinical, neuropsychological and functional differences
2017
BACKGROUND: Numerous studies show the existence of a high prevalence of cannabis use among patients with psychosis. However, the differences between men and women who debut with a first episode of psychosis (FEP) regarding cannabis use have not been largely explored. The aim of this study was to identify the specific sex factors and differences in clinical evolution associated with cannabis use. METHOD: Sociodemographic characteristics at baseline were considered in our sample of FEP patients to find differences depending on sex and the use of cannabis. Clinical, functional and neurocognitive variables at baseline, 1-year, and 3-years follow-up were also explored. RESULTS: A total of 549 pa…
In utero Δ9-tetrahydrocannabinol exposure confers vulnerability towards cognitive impairments and alcohol drinking in the adolescent offspring: Is th…
2020
Background:Cannabinoid consumption during pregnancy has been increasing on the wave of the broad-based legalisation of cannabis in Western countries, raising concern about the putative detrimental outcomes on foetal neurodevelopment. Indeed, since the endocannabinoid system regulates synaptic plasticity, emotional and cognitive processes from early stages of life interfering with it and other excitability endogenous modulators, such as neuropeptide Y (NPY), might contribute to the occurrence of a vulnerable phenotype later in life.Aims:This research investigated whether in utero exposure to Δ9-tetrahydrocannabinol (THC) may induce deficits in emotional/cognitive processes and alcohol vulner…
Conceptual implicit memory: a developmental study.
1995
The widely accepted standpoint that implicit memory emerges earlier in development than explicit memory, and is more stable from childhood to adult age, is based on experimental data essentially collected in perceptual tasks. The present study was aimed at investigating whether these findings still hold when a more conceptual task is used. We compared the performance of children at two age levels (2nd and 4th grades) on a category-exemplar generation task. Results showed that performances of the two groups were comparable when the target items were typical of their categories, as in Experiment 2, and for a subset of the items in Experiment 1. However, the older children outperformed the you…
What makes working memory spans so predictive of high-level cognition?
2005
Working memory (WM) span tasks involving a complex activity performed concurrently with item retention have proven to be good predictors of high-level cognitive performance. The present study demonstrates that replacing these complex self-paced activities with simpler but computer-paced processes, such as reading successive letters, yields more predictive WM span measures. This finding suggests that WM span tasks evaluate a fundamental capacity that underpins complex as well as elementary cognitive processes. Moreover, the higher predictive power of computer-paced WM span tasks suggests that strategic factors do not contribute to the relationship between WM spans and high-level cognition.
Working Memory Task Influence in Postural Stability and Cognitive Function in Adolescents.
2018
This paper describes a study on postural stability and cognitive function according to the difficulty increment of a working memory task (WMT) and age group in adolescents. One hundred and twenty-three participants (13–16 years) performed single and dual tasks in a bipedal standing position while barefoot. Four trials were conducted, consisting of single and dual tasks in three progressively difficult WMT conditions (i.e., 3-, 5-, and 7-digit sequences). Friedman’s analysis of variance and Kruskal–Wallis tests were conducted to test the effect of the WMT and age group, respectively. Both the WMT and age were found to affect performance (p < .01). As the cognitive requirements increased, the…
The cortisol awakening response and memory performance in older men and women.
2012
Summary The activity and regulation of the hypothalamus-pituitary-adrenal axis has been related to cognitive decline during aging. This study investigated whether the cortisol awakening response (CAR) is related to memory performance among older adults. The sample was composed of 88 participants (44 men and 44 women) from 55 to 77 years old. The memory assessment consisted of two tests measuring declarative memory (a paragraph recall test and a word list learning test) and two tests measuring working memory (a spatial span test and a spatial working memory test). Among those participants who showed the CAR on two consecutive days, we found that a greater CAR was related to poorer declarativ…
Children's brain responses to sound changes in pseudo words in a multifeature paradigm.
2011
Abstract Objective The multifeature mismatch negativity (MMN) paradigm has previously been used to study MMN responses to changes in tones or isolated syllables. We tested 4–12year old children's MMNs to changes in a naturally produced pseudo word context. Methods We studied preschoolers' (under the age of 7years, N =15, mean age 5years 4months) and school childrens' (over the age of 7years, N =15, mean age 9years 3months) MMNs to five types of changes (vowel duration, fundamental frequency, gap, intensity, vowel identity) in the middle syllable of a pseudo word [tɑtɑtɑ] using a multifeature paradigm. Results Vowel duration and gap changes elicited larger frontocentral MMN responses than ot…
Neurocognitive and clinical predictors of functional outcome in patients with schizophrenia and bipolar I disorder at one-year follow-up
2007
Abstract Objective Many studies have reported that cognitive ability may be predictive of the functional outcome for patients with schizophrenia. However, no study has prospectively examined these aspects in schizophrenia and bipolar disorders simultaneously. The present study attempted to analyze if neurocognition and clinical status predicts the real-life functioning for patients with schizophrenia or bipolar I disorder, using a longitudinal design. Method Forty-seven schizophrenic and 43 bipolar I outpatients were assessed twice with a neurocognitive battery (Executive Functions, Working Memory, Verbal Memory, Visual Memory, Visual-Motor Processing, Vigilance, Vocabulary and Motor Speed …
Persistent psychogenic déjà vu: a case report.
2014
Introduction: Déjà vu is typically a transient mental state in which a novel experience feels highly familiar. Although extensively studied in relation to temporal lobe epilepsy as part of simple partial seizures, déjà vu has been less studied in other clinical populations. A recent review of temporal lobe epilepsy suggested a possible link between clinical levels of anxiety and debilitating déjà vu, indicating further research is required. Here, for the first time in the literature, we present a case study of a young man with anxiety and depersonalisation who reported experiencing persistent and debilitating déjà vu. This report therefore adds to the limited literature on the relationship …
Functional relevant loss of long association fibre tracts integrity in early Alzheimer's disease.
2007
Abstract The aim of our study was to quantify the structural integrity of the long association fibre tracts in early Alzheimer's disease (AD) and to correlate the findings with the cognitive performance of the patients. We conducted region-of-interest-based analyses of color-coded diffusion-tensor imaging in 12 patients with early AD (age 69.8 ± 8.0 years; MMSE 25.3 ± 1.8) and 16 age- and education-matched healthy controls. Early AD patients showed significantly decreased fractional anisotropy (FA) of the cingulate bundles and the inferior fronto-occipital fascicles bilaterally, whereas FA values of the superior longitudinal fascicles (second division) did not differ significantly between p…