Search results for " methodology."
showing 10 items of 520 documents
The conditional censored graphical lasso estimator
2020
© 2020, Springer Science+Business Media, LLC, part of Springer Nature. In many applied fields, such as genomics, different types of data are collected on the same system, and it is not uncommon that some of these datasets are subject to censoring as a result of the measurement technologies used, such as data generated by polymerase chain reactions and flow cytometer. When the overall objective is that of network inference, at possibly different levels of a system, information coming from different sources and/or different steps of the analysis can be integrated into one model with the use of conditional graphical models. In this paper, we develop a doubly penalized inferential procedure for…
A computationally fast alternative to cross-validation in penalized Gaussian graphical models
2015
We study the problem of selection of regularization parameter in penalized Gaussian graphical models. When the goal is to obtain the model with good predicting power, cross validation is the gold standard. We present a new estimator of Kullback-Leibler loss in Gaussian Graphical model which provides a computationally fast alternative to cross-validation. The estimator is obtained by approximating leave-one-out-cross validation. Our approach is demonstrated on simulated data sets for various types of graphs. The proposed formula exhibits superior performance, especially in the typical small sample size scenario, compared to other available alternatives to cross validation, such as Akaike's i…
Multiscale Granger causality
2017
In the study of complex physical and biological systems represented by multivariate stochastic processes, an issue of great relevance is the description of the system dynamics spanning multiple temporal scales. While methods to assess the dynamic complexity of individual processes at different time scales are well-established, multiscale analysis of directed interactions has never been formalized theoretically, and empirical evaluations are complicated by practical issues such as filtering and downsampling. Here we extend the very popular measure of Granger causality (GC), a prominent tool for assessing directed lagged interactions between joint processes, to quantify information transfer a…
Multivariate nonparametric estimation of the Pickands dependence function using Bernstein polynomials
2017
Abstract Many applications in risk analysis require the estimation of the dependence among multivariate maxima, especially in environmental sciences. Such dependence can be described by the Pickands dependence function of the underlying extreme-value copula. Here, a nonparametric estimator is constructed as the sample equivalent of a multivariate extension of the madogram. Shape constraints on the family of Pickands dependence functions are taken into account by means of a representation in terms of Bernstein polynomials. The large-sample theory of the estimator is developed and its finite-sample performance is evaluated with a simulation study. The approach is illustrated with a dataset of…
Identifying Causal Effects with the R Package causaleffect
2017
Do-calculus is concerned with estimating the interventional distribution of an action from the observed joint probability distribution of the variables in a given causal structure. All identifiable causal effects can be derived using the rules of do-calculus, but the rules themselves do not give any direct indication whether the effect in question is identifiable or not. Shpitser and Pearl constructed an algorithm for identifying joint interventional distributions in causal models, which contain unobserved variables and induce directed acyclic graphs. This algorithm can be seen as a repeated application of the rules of do-calculus and known properties of probabilities, and it ultimately eit…
Blind source separation for non-stationary random fields
2022
Regional data analysis is concerned with the analysis and modeling of measurements that are spatially separated by specifically accounting for typical features of such data. Namely, measurements in close proximity tend to be more similar than the ones further separated. This might hold also true for cross-dependencies when multivariate spatial data is considered. Often, scientists are interested in linear transformations of such data which are easy to interpret and might be used as dimension reduction. Recently, for that purpose spatial blind source separation (SBSS) was introduced which assumes that the observed data are formed by a linear mixture of uncorrelated, weakly stationary random …
Confidence bands for Horvitz-Thompson estimators using sampled noisy functional data
2013
When collections of functional data are too large to be exhaustively observed, survey sampling techniques provide an effective way to estimate global quantities such as the population mean function. Assuming functional data are collected from a finite population according to a probabilistic sampling scheme, with the measurements being discrete in time and noisy, we propose to first smooth the sampled trajectories with local polynomials and then estimate the mean function with a Horvitz-Thompson estimator. Under mild conditions on the population size, observation times, regularity of the trajectories, sampling scheme, and smoothing bandwidth, we prove a Central Limit theorem in the space of …
Bayesian models for data missing not at random in health examination surveys
2018
In epidemiological surveys, data missing not at random (MNAR) due to survey nonresponse may potentially lead to a bias in the risk factor estimates. We propose an approach based on Bayesian data augmentation and survival modelling to reduce the nonresponse bias. The approach requires additional information based on follow-up data. We present a case study of smoking prevalence using FINRISK data collected between 1972 and 2007 with a follow-up to the end of 2012 and compare it to other commonly applied missing at random (MAR) imputation approaches. A simulation experiment is carried out to study the validity of the approaches. Our approach appears to reduce the nonresponse bias substantially…
Deducing self-interaction in eye movement data using sequential spatial point processes
2016
Eye movement data are outputs of an analyser tracking the gaze when a person is inspecting a scene. These kind of data are of increasing importance in scientific research as well as in applications, e.g. in marketing and man-machine interface planning. Thus the new areas of application call for advanced analysis tools. Our research objective is to suggest statistical modelling of eye movement sequences using sequential spatial point processes, which decomposes the variation in data into structural components having interpretation. We consider three elements of an eye movement sequence: heterogeneity of the target space, contextuality between subsequent movements, and time-dependent behaviou…
Purification of recovered phosphoric acid by extracting aluminium with di-2-ethylhexyl phosphoric acid
2021
AbstractThe extraction of aluminium from dilute phosphoric acid with di-2-ethylhexyl phosphoric acid (DEHPA) was optimized using response surface methodology. The optimization was based on the experimental three-level central composite face-centred design (CCF) and was conducted on real-life samples. The three variables included were pH, extractant concentration and aqueous to organic phase ratio (AO). Under the optimized conditions (pH 2.5, 0.6 M DEHPA and AO ratio 1:2), extraction efficiency of 99% for aluminium in four extraction stages is achieved. The purified phosphoric acid solution can then be utilized by the fertilizing industry. Stripping tests for organic phase loaded with alumin…