Search results for " middle"

showing 10 items of 1097 documents

Canine fossa puncture in endoscopic sinus surgery: report of two cases

2017

Abstract Introduction Chronic rhinosinusitis with nasal polyposis is a common chronic disease that often affects maxillary sinus. Endoscopic sinus surgery is the most common procedure for treating the majority of maxillary sinus lesions. Objective To demonstrate the role of canine fossa puncture during endoscopic sinus surgery procedure in patients with severe maxillary sinus disease. Methods We present 2 cases where canine fossa puncture has been performed as method to obtain a complete access to the maxillary antrum. Results According our experience, 2 cases on 296 endoscopic sinus surgery (0.6%) where antrostomy and used of angled microdebrider were not sufficient, canine fossa puncture …

medicine.medical_specialtyMaxillary sinusChronic rhinosinusitissinusitisCanine fossa punctureMiddle meatal antrostomyPuncturesMaxillary antrumMaxillary sinusYoung Adult03 medical and health sciencesNasal Polyps0302 clinical medicineMaxillary sinusitisotorhinolaryngologic diseasesmedicineHumansIn patient030223 otorhinolaryngologyAgedMaxillary sinus sinusitis Maxillary sinusitisAlternative methodsAngled microdebriderbusiness.industryOtorhinolaryngology2734 Pathology and Forensic MedicineEndoscopylcsh:Otorhinolaryngologylcsh:RF1-547SurgeryEndoscopic sinus surgerymedicine.anatomical_structureChronic diseaseOtorhinolaryngologyCanine fossaAngled microdebrider; Canine fossa puncture; Maxillary sinusitis; Middle meatal antrostomy; Otorhinolaryngology2734 Pathology and Forensic MedicineChronic DiseaseFemaleTomography X-Ray Computedbusiness030217 neurology & neurosurgery
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Double localization and multiple recurrences of dermatofibrosarcoma protuberans of the female breast: a rare clinical case.

2015

Not available

medicine.medical_specialtySkin NeoplasmsMEDLINEBreast NeoplasmsNeoplasm RecurrenceInternal MedicinemedicineDermatofibrosarcoma protuberansBreast Neoplasms; Dermatofibrosarcoma; Female; Humans; Middle Aged; Neoplasm Recurrence Local; Skin Neoplasms; Internal Medicine; Oncology; Surgery; Medicine (all)HumansSkin NeoplasmUltrasonographybusiness.industryMedicine (all)DermatofibrosarcomaMiddle Agedmedicine.diseaseSurgeryOncologySurgeryFemaleRadiologyClinical caseUltrasonographyNeoplasm Recurrence LocalbusinessBreast NeoplasmDermatofibrosarcomaHumanThe breast journal
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Neurochemistry of identified motoneurons of the tensor tympani muscle in rat middle ear

2008

The objective of the present study was to identify efferent and afferent transmitters of motoneurons of the tensor tympani muscle (MoTTM) to gain more insight into the neuronal regulation of the muscle. To identify MoTTM, we injected the fluorescent neuronal tracer Fluoro-Gold (FG) into the muscle after preparation of the middle ear in adult rats. Upon terminal uptake and retrograde neuronal transport, we observed FG in neurons located lateral and ventrolateral to the motor trigeminal nucleus ipsilateral to the injection site. Immunohistochemical studies of these motoneurons showed that apparently all contained choline acetyltransferase, demonstrating their motoneuronal character. Different…

medicine.medical_specialtyStilbamidinesEar MiddleNeuropeptideSubstance PCalcitonin gene-related peptideInjections IntramuscularTensor tympani muscleCholine O-AcetyltransferaseRats Sprague-Dawleychemistry.chemical_compoundInternal medicinemedicineAnimalsNeuronal transportFluorescent DyesMotor NeuronsStaining and LabelingTyrosine hydroxylaseChemistryNeuropeptidesNeurochemistryNeuropeptide Y receptorImmunohistochemistryCholine acetyltransferaseSensory SystemsRatsEndocrinologynervous systemFemaleTensor TympaniHearing Research
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Air pollution and stroke. A new modifiable risk factor is in the air

2019

Abstract Evidence from epidemiological studies has demonstrated that outdoor air pollution is now a well-known major problem of public health, mainly in low and middle income countries. Contrasting with myocardial infarction , there are few data on the association of air pollution and stroke. Methods We propose a narrative literature review of the effects and the underlying biological mechanisms of short- and long-term exposure to air pollutants on stroke risk and mortality, using the following key-words: stroke, cerebrovascular events, ischemic and haemorrhage stroke, transient ischaemic attack , mortality, air pollution and air pollutants. Results Twenty-one papers were selected. Air poll…

medicine.medical_specialty[SDV]Life Sciences [q-bio]Air pollutionComorbiditymedicine.disease_causeEffect Modifier Epidemiologic03 medical and health sciences0302 clinical medicineRisk FactorsEnvironmental healthAir PollutionEpidemiologymedicineHumanscardiovascular diseases030212 general & internal medicineMyocardial infarctionRisk factorStrokeInhalation Exposurebusiness.industryPublic healthMortality ratemedicine.disease3. Good healthStrokeNeurologyLow and middle income countriesIschemic Attack TransientParticulate MatterNeurology (clinical)business030217 neurology & neurosurgery
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Surgical Management of Retraction Pockets: Does Mastoidectomy have a Role?

2021

Abstract Introduction Retraction pocket is a condition in which the eardrum lies deeper within the middle ear. Its management has no consensus in literature. Objective To assess the role of mastoidectomy in the management of retraction pockets added to a tympanoplasty. Methods Prospective study of patients with retraction pocket and referred to surgery. The patients were randomly assigned to two groups: one managed with tympanoplasty and mastoidectomy and the other group with tympanoplasty only. The minimum follow-up considered was 12 months. The outcomes were: integrity of eardrum, recurrence, and hearing status. Results This study included 43 patients. In 24 cases retraction occurred in t…

medicine.medical_specialtymastoidectomymedicine.medical_treatmentlcsh:MedicineMastoidectomyMastoidectomy Middle ear Ossiculoplasty Otitis media Tympanic membrane Tympanoplasty03 medical and health sciences0302 clinical medicinetympanoplastymedicineossiculoplasty030223 otorhinolaryngologyOriginal Researchtympanic membraneOssicular chainAir volumebusiness.industrylcsh:Rotitis mediaTympanoplastylcsh:Otorhinolaryngologylcsh:RF1-547Settore MED/32 - AudiologiaSurgerySettore MED/31 - Otorinolaringoiatriamedicine.anatomical_structureOtorhinolaryngologymiddle ear030220 oncology & carcinogenesisMiddle earbusinessEardrumHearing.statusRetraction pocketInternational Archives of Otorhinolaryngology
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Multimorbidity and anxiety symptoms among adults aged 50 years and over from six low- and middle-income countries

2021

Currently, there are limited data on the association between multimorbidity (i.e., ≥ 2 chronic conditions) and anxiety, especially among the older population in low- and middle-income countries (LMICs). Thus, the aim of the present study was to examine the association between multimorbidity and anxiety symptoms in a large sample of adults aged ≥ 50 years from six LMICs (China, India, Ghana, Mexico, Russia, South Africa). Cross-sectional, nationally representative, community-based data from the Study on Global Ageing and Adult Health (SAGE) were analysed. A total of 11 chronic physical conditions were assessed. Anxiety symptoms referred to extreme/severe problems with worry or anxiety in the…

medicine.medical_specialtymultimorbiditybusiness.industrymedia_common.quotation_subjectmulticountryLogistic regressionanxietyOddsOlder populationLow and middle income countriesEpidemiologymedicineAnxietySmıth L. F. López Sánchez G. Shin J. I. Soysal P. Veronese N. -Multimorbidity and Anxiety Symptoms among Adults Aged 50 Years and Over from Six Low- and Middle-Income Countries- Journal of Ageing and Longevity cilt.1 sa.1 ss.36-47 2021epidemiologylow- and middle-income countriesmedicine.symptomWorrybusinessAdult healtholder adultsDemographymedia_common
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Tubular carcinoma of the breast: Outcome and loco-regional recurrence in 307 patients

2005

Abstract Purpose The aim of this study is to describe the University of Florence experience in evaluating clinical, pathologic and treatment factors as they are related to the outcome and loco-regional recurrence in patients with tubular breast carcinoma. Material and methods Three hundred and seven patients (median age 56.4 years, range 26–91 years) with histological verified tubular carcinoma of the breast were consecutively treated at University of Florence from 1976 to 2001. All patients were followed for a median of 8.4 years (range 3 months to 20 years). Thirty-seven women underwent mastectomy and 270 underwent breast conserving surgery. Positive axillary nodes were found in 15% of pa…

medicine.medical_treatmentDiseaseSegmentalMastectomy SegmentalBreast cancerDuctalBreast-conserving surgery80 and overBreastAdjuvantMastectomyAged 80 and overCarcinoma Ductal BreastTubular carcinomaGeneral MedicineMiddle AgedCombined Modality TherapyTreatment OutcomeBreast cancer; Radiotherapy; Tubular carcinoma; Adenocarcinoma; Adult; Aged; Aged 80 and over; Antineoplastic Agents Hormonal; Axilla; Breast Neoplasms; Carcinoma Ductal Breast; Chemotherapy Adjuvant; Combined Modality Therapy; Female; Humans; Lymphatic Metastasis; Mastectomy; Mastectomy Segmental; Middle Aged; Neoplasm Recurrence Local; Proportional Hazards Models; Radiotherapy Adjuvant; Survival Analysis; Tamoxifen; Treatment Outcome; Oncology; SurgeryLocalOncologyChemotherapy AdjuvantLymphatic MetastasisFemaleMastectomymedicine.drugAdultmedicine.medical_specialtyAntineoplastic Agents HormonalAntineoplastic AgentsBreast NeoplasmsAdenocarcinomaBreast cancermedicineChemotherapyHumansAgedProportional Hazards ModelsChemotherapyRadiotherapyHormonalbusiness.industryCarcinomamedicine.diseaseSurvival AnalysisSurgeryRadiation therapyTamoxifenNeoplasm RecurrenceAxillaRadiotherapy AdjuvantSurgeryTubular carcinomaNeoplasm Recurrence LocalbusinessTamoxifen
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Is COVID‐19 infection more severe in kidney transplant recipients?

2021

International audience; There are no studies which have compared the risk of severe Covid-19 and related mortality between transplant recipients and non-transplant patients. We enrolled two groups of patients hospitalized for Covid-19, i.e., kidney transplant recipients from the French Registry of Solid Organ Transplant (n=306) and a single-center cohort of non-transplant patients (n=795). An analysis was performed among subgroups matched for age and risk factors for severe Covid-19 or mortality. Severe Covid-19 was defined as admission (or transfer) to an intensive care unit, need for mechanical ventilation, or death.Transplant recipients were younger and had more comorbidities compared to…

medicine.medical_treatment[SDV]Life Sciences [q-bio]MESH: Registries*AucunMESH: Comorbidity030230 surgerylaw.inventionchemistry.chemical_compound0302 clinical medicinelawcardiovascular diseaseMESH: Risk Factors[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseasesclinical research / practiceImmunology and AllergyCumulative incidencePharmacology (medical)kidney transplantation / nephrologyMESH: IncidenceMESH: AgedUnivariate analysisMESH: France / epidemiologyMESH: Middle AgedMESH: Transplant Recipients / statistics & numerical data*Acute kidney injuryIntensive care unit3. Good healthMESH: COVID-19 / epidemiologyCohort[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseasesglomerular filtration rate (GFR)kidney failure / injurymedicine.medical_specialtyinfection and infectious agents - viralinfectious diseaseBrief CommunicationMESH: Graft Rejection / prevention & control03 medical and health sciencesInternal medicineDiabetes mellitusMESH: Severity of Illness IndexMESH: COVID-19 / diagnosis*medicineHumansMESH: SARS-CoV-2Mechanical ventilationCreatinineTransplantationMESH: Humansbusiness.industrySARS-CoV-2MESH: Graft Rejection / epidemiology*COVID-19MESH: Retrospective Studiesmedicine.diseaseKidney TransplantationTransplant RecipientsMESH: Maleimmunosuppressive regimensMESH: Immunosuppressive Agents / therapeutic useMESH: Pandemics*MESH: Propensity Score*chemistryReinfectionMESH: Immunosuppression / methodsMESH: Intensive Care UnitsbusinessMESH: FemaleMESH: Kidney Transplantation*
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Monastères et espace urbain au haut Moyen Âge

2012

In both episcopal cities studied here, Auxerre and Autun, in Burgundy, the sites chosen for the establishment of monasteries can be partly determined by their functions, more or less restrictive. The most frequent in the cities are communities of monks settled in the seventh-eighth centuries to serve a funerary basilica or a tomb. This function involves an extra muros situation whatever the age of the foundation of the basilica. Inside the cities, truly monasteries, that is to say, communities of ascetics, are few; these are located outside the walls, but, although isolated from the city by the rampart, these remain in contact with it by symbolic functions. Unlike that is attested in Autun …

monasteries[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistorymonastèrescités épiscopaleshaut moyen âge[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistorytopographie religieuseurban topographyepiscopal citiesreligious topography[ SHS.ARCHEO ] Humanities and Social Sciences/Archaeology and Prehistoryearly and high middle agesBourgognetopographie urbaineBurgundy
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The soluble terminal complement complex (SC5b-9) up-regulates osteoprotegerin expression and release by endothelial cells: Implications in rheumatoid…

2009

Objective. Complement activation products contribute to a large number of inflammatory diseases, including RA. We have investigated whether osteoprotegerin (OPG) may concur with the soluble terminal complement complex (SC5b-9) to the inflammatory cascade characterizing RA. Methods. Levels of SC5b-9 and OPG in the plasma and SF of patients with active RA were determined by ELISA. The presence of SC5b-9 and OPG in RA synovial lesions was analysed by immunohistochemistry. Cultured endothelial cells were used for in vitro leucocyte/endothelial cell adhesion assays. In addition, endothelial cells were exposed to SC5b-9 in order to evaluate the effects on the production of OPG protein, as well as…

musculoskeletal diseasesAdultMalemedicine.medical_specialtyComplement systemEndotheliumNeutrophilsArthritisInflammationComplement Membrane Attack ComplexArthritis RheumatoidEndothelium; Osteoprotegerin; Inflammation; Complement systemRheumatologyOsteoprotegerinInternal medicineCell AdhesionMedicineHumansPharmacology (medical)EndotheliumCells CulturedAgedInflammationEndothelial CellDose-Response Relationship Drugbusiness.industryNeutrophilSynovial MembraneOsteoprotegerinEndothelial CellsMiddle Agedmedicine.diseaseIn vitroComplement systemUp-RegulationEndothelial stem cellEndocrinologymedicine.anatomical_structureNeutrophil InfiltrationFemaleComplement system; Endothelium; Inflammation; Osteoprotegerin; Adult; Aged; Arthritis Rheumatoid; Cell Adhesion; Cells Cultured; Complement Membrane Attack Complex; Dose-Response Relationship Drug; Endothelial Cells; Endothelium Vascular; Female; Humans; Male; Middle Aged; Neutrophil Infiltration; Neutrophils; Osteoprotegerin; Synovial Membrane; Up-Regulation; Rheumatology; Pharmacology (medical)Endothelium Vascularmedicine.symptombusinessComplement membrane attack complexHuman
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