Search results for " migration."
showing 10 items of 718 documents
7keto-stigmasterol and 7keto-cholesterol induce differential proteome changes to intestinal epitelial (Caco-2) cells
2015
Abstract Recent studies have expanded the appreciation of the roles of oxysterols triggering inflammatory, immune cytotoxic and apoptotic processes, but have not been considered for proteome analysis. A comparative proteomic study in intestinal epithelial cell cultures incubated (60 μM/24 h) with 7keto-cholesterol or 7keto-stigmasterol was performed. The influence of both compounds was studied following the nLC-TripleTOF analysis. Findings were compared to results for control cultures. In the principal component analysis (PCA) of proteome patterns, two components were extracted accounting for 99.8% of the variance in the protein expression. PCA analysis clearly discriminated between the per…
Bioinformatic and experimental fishing for artemisinin-interacting proteins from human nasopharyngeal cancer cells.
2012
Determining interacting cellular partners of drugs by chemical proteomic techniques is complex and tedious. Most approaches rely on activity-based probe profiling and compound-centric chemical proteomics. The anti-malarial artemisinin also exerts profound anti-cancer activity, but the mechanisms of action are incompletely understood. In the present investigation, we present a novel approach to identify artemisinin-interacting target proteins. Our approach overcomes usual problems in traditional fishing procedures, because the drug was attached to a surface without further chemical modification. The proteins identified effect among others, cell cycle arrest, apoptosis, inhibition of angiogen…
Working conditions and their impact on work satisfaction in migrating and non migrating workers. Factor structure of the Polish version of the Workin…
2020
BackgroundThe study compares the impact of working conditions and wages as predictors of work satisfaction of Poles, working in Poland and abroad. Although the work environment plays a crucial role in determining the work sat-isfaction of migrants, most mention higher income abroad as the main migration motive. The increased in-come may not boost the work satisfaction however, because during migration the wage reference point chang-es. Based on those observations, it was assumed that working conditions will have a greater impact on mi-grants’ work satisfaction than nominal earnings. Additionally, migrants, while having higher nominal wages, should subjectively judge them as lower.Participan…
Migration history and risk of psychosis: results from the multinational EU-GEI study.
2022
The European Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI) Project was funded by grant agreement Health-F2-2010-241909 (Project EU-GEI) from the European Community’s Seventh Framework programme.
Indoor air pollutants stimulate interleukin-8-specific mRNA expression and protein secretion of alveolar macrophages.
1998
Indoor air pollutants may cause inflammatory changes of the airways and adjacent pulmonary tissue. After phagocytosis of inhaled particles alveolar macrophages (AM) release chemotactic mediators capable of attracting inflammatory cells into the lung tissue. To evaluate these mechanisms further peripheral blood mononuclear cells (PBMNC) and human AM (freshly recovered from the lower respiratory tract) were exposed to the indoor particles Soot FR 101 and Printex 90, the asbestos fiber Chrysotile B, and titanium dioxide (TiO2) at concentrations of 10 or 50 microg/10(6) cells for up to 8 h. The migration of granulocytes into the conditioned supernatants of AM and PBMNC was quantified by chemota…
Diet of the insectivorous bat 'Pipistrellus nathusii' during autumn migration and summer residence
2013
Migration is widespread among vertebrates, yet bat migration has received little attention and only in the recent decades has a better understanding of it been gained. Migration can cause significant changes in behaviour and physiology, due to increasing energy demands and aerodynamic constraints. Dietary shifts, for example, have been shown to occur in birds before onset of migration. For bats, it is not known if a change in diet occurs during migration, although breeding season–related dietary preference has been documented. It is known that a diet rich in fats and the accumulation of fat deposits do increase the flight range of migratory bats. Some bat species can be regarded as long-dis…
Remittance behaviours of foreigners in Italy
2013
This paper intends to figure out why immigrants remit, what characteristics they have and, in particular, which of these individual characteristics influence (and in what sense) their remittance behaviours. In particular, it aims to verify the existence of a "time effect" during the migration process. The time effect supposes that the propensity and amount of remittances become less consistent as far as the immigrant integrates into the host country and the ties with the country of origin become less intense. In practice, according to this hypothesis, the evolution of the migration plan towards stabilisation in the new country, rather than to return home, would lead the migrant to invest mo…
Filamentous fungi transported by birds during migration across the mediterranean sea.
2013
The potential for the transport and diffusion of some pathogenic microorganisms by migratory birds is of concern. Migratory birds may be involved in the dispersal of microorganisms and may play a role of mechanical and biological vectors. The efficiency of dispersal of pathogenic microorganisms depends on a wide range of biotic and abiotic factors that influence the survival or disappearance of a given agent in a geographical area. In the present study, 349 migratory birds were captured in four sites (Mazara del Vallo, Lampedusa, Ustica and Linosa), representing the main stop-over points during spring and autumnal migration, and analyzed for the presence of filamentous fungi. A total of 2,3…
Values, cities and migrations. Real estate market and social system in a multi-cultural city
2023
The book consists of seventeen papers in two parts. The first part, “Values and Relationship Systems in Multicultural Societies”, features how social sciences––including appraisal and valuation, urban planning, philosophy, psychology, and geography––take different approaches to studying values and relationships, converging to form a unified mosaic of complementary and interconnected knowledge. The second part, “Transformations, Permeability and Permanence of Values in Contemporary Multicultural Cities”, highlights the most crucial topics on which appraisals and models focus to interpret and represent the influence of migration on the real estate market in different urban and territorial con…
Macrophage migration inhibitory factor is critically involved in basal and fluoxetine-stimulated adult hippocampal cell proliferation and in anxiety,…
2011
Intensive research is devoted to unravel the neurobiological mechanisms mediating adult hippocampal neurogenesis, its regulation by antidepressants, and its behavioral consequences. Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine that is expressed in the CNS, where its function is unknown. Here, we show, for the first time, the relevance of MIF expression for adult hippocampal neurogenesis. We identify MIF expression in neurogenic cells (in stem cells, cells undergoing proliferation, and in newly proliferated cells undergoing maturation) in the subgranular zone of the rodent dentate gyrus. A causal function for MIF in cell proliferation was shown using genetic (M…