Search results for " mining"

Artificial increase of uracilemia during fluoropyrimidine treatment can lead to DPD deficiency misinterpretation

2021

Each year in France, >75 000 patients receive fluoropyrimidines, including 5-fluorouracil (5-FU) and its oral prodrug capecitabine (Xeloda), to treat digestive, breast and head and neck cancers.1 Among them, ∼20% will experience severe hematological and digestive toxicities and <2% will have a fatal outcome in the first two cycles. A part of these toxicities may result from a deficiency in dihydropyrimidine dehydrogenase (DPD) which catabolizes the endogenous uracil (U) into dihydrouracil (UH2) as well as 5-FU. In 2018, French Health Authorities [Haute Autorité de Santé (HAS) and Institut National du Cancer, (INCa)] recommended the evaluation of the enzymatic activity of DPD by measuring th…

An Heuristic Approach for the Training Dataset Selection in Fingerprint Classification Tasks

2015

Fingerprint classification is a key issue in automatic fingerprint identification systems. It aims to reduce the item search time within the fingerprint database without affecting the accuracy rate. In this paper an heuristic approach using only the directional image information for the training dataset selection in fingerprint classification tasks is described. The method combines a Fuzzy C-Means clustering method and a Naive Bayes Classifier and it is composed of three modules: the first module builds the working datasets, the second module extracts the training images dataset and, finally, the third module classifies fingerprint images in four classes. Unlike literature approaches using …

Experimental Models of Autoimmune Hepatitis

1991

Chromosomal and genetic changes produced in tumoral progression of embryonal rhabdomyosarcoma

2013

Collaborative Assessment of Information Provider's Reliability and Expertise Using Subjective Logic

2011

QA each user can individually estimate the expertise and the reliability of her peers using her direct interactions with them and our framework. The online SN (OSN), which can be considered as a distributed database, performs continuous data aggregation for users expertise and reliability assessment in order to reach a consensus. We emulate a Q&A SN to examine various performance aspects of our algorithm (e.g., convergence time, responsiveness etc.). Our evaluations indicate that it can accurately assess the reliability and the expertise of a user with a small number of samples and can successfully react to the latter's behavior change, provided that the cognitive traits hold in practice.

Functional Relations Between the Caudate Nucleus and the Dorsal Hippocampus in the Cat

1972

Response to "Evaluation of transverse dorsal lumbotomy in management of PUJ obstruction in patients younger than 6 months".

2021

Breakthrough pain: On the road again

2009

Preemptive analgesia-related gene and protein expression in third molar surgeries under non steroidal anti-inflammatory drug protocols : A PROSPERO-r…

2018

Background This study aimed to review translational studies focusing on third molar removal surgeries through a systematic analytical approach. Material and Methods A PROSPERO-registered systematic review (CRD42017060455) was conducted following the PRISMA statement to summarize current knowledge on gene expression in third molar surgeries. A search was performed in PubMed’s Medline and Scopus databases, without date or language restrictions, using the logical expression {[(Third molar) OR (preemptive) OR (cyclooxygenase inhibitors) OR (acute inflammation) AND (gene expression)]}. Results All studies included in the analysis evaluated gene expression in a third molar extraction model, using…

Does Metformin Modulate Mitochondrial Dynamics and Function in Type 2 Diabetic Patients?

2021

Metformin is an effective drug against type 2 diabetes (T2D), a pathogenesis in which mitochondrial dysfunction is one of the main players. Thus, our first aim was to describe the effect of metform...