Search results for " modifica"

La religión del cuerpo-mercancía: ¿un nuevo opio del pueblo?

2018

The commercial exploitation or more precisely the total capitalist management of the human body erects this as a universal divinity. The direct consequence of this generalized corporal capitalism is the massive depoliticization of the body and, often, the reflection that is dedicated to it. In this article, we seek to reflect on the current practices of bodily modifications within the framework of the changes in the regimes of neoliberal governance in recent decades. This reflection is guided by the revision of central texts of critical theory

Ti6Al4V Surface Modification Techniques to Modulate Bone Cell Response: A Review

2022

Biomaterial-tissue interactions are known to largely affect implant performance, relating to alteration of physiological processes. Within this context, metals continue to have a major role as most implants contain at least one metallic part. In particular, titanium alloys are of pivotal importance in orthopedics and dentistry. Being osteointegration somewhat affected by implant surface conditions, surface modifications, surface modification qualify as a way to modulate tissue response, net of an effective design of the whole implant. Currently, a lack of full understanding on the direction to be taken for proper techniques and process conditions to be employed, for the regulation of osteoi…

Electrochemical C−H Functionalization of (Hetero)Arenes—Optimized by DoE

2020

Abstract A novel approach towards the activation of different arenes and purines including caffeine and theophylline is presented. The simple, safe and scalable electrochemical synthesis of 1,1,1,3,3,3‐hexafluoroisopropanol (HFIP) aryl ethers was conducted using an easy electrolysis setup with boron‐doped diamond (BDD) electrodes. Good yields up to 59 % were achieved. Triethylamine was used as a base as it forms a highly conductive media with HFIP, making additional supporting electrolytes superfluous. The synthesis was optimized using Design of Experiment (DoE) techniques giving a detailed insight to the significance of the reaction parameters. The mechanism was investigated by cyclic volt…

Editorial: Physiology and Pathophysiology of Heat Shock Protein 60

2020

Multifibrillar bundles of a self-assembling hyaluronic acid derivative obtained through a microfluidic technique for aortic smooth muscle cell orient…

2018

A hyaluronic acid derivative that is able to physically crosslink in a saline aqueous environment was employed for the production of fibers with a mean diameter of 50 μm using a microfluidic technique. The microfibers were collected in a tailored rotating collector and assembled to form multifibrillar bundles. The orientation of the microfibers on the collected bundles was evaluated by microCT analysis. The bundles were biofunctionalized by physical addition of fibronectin or chemical tethering of a cyRGDC peptide to achieve control of Aortic Smooth Muscle Cell (AoSMC) attachment, elongation and alignment. The mechanical performances of these bundles were evaluated by elongation tests, rela…

Is the ADA/EASD algorithm for the management of type 2 diabetes (January 2009) based on evidence or opinion? A critical analysis

2010

The ADA and the EASD recently published a consensus statement for the medical management of hyperglycaemia in patients with type 2 diabetes. The authors advocate initial treatment with metformin monotherapy and lifestyle modification, followed by addition of basal insulin or a sulfonylurea if glycaemic goals are not met (tier 1 recommendations). All other glucose-lowering therapies are relegated to a secondary (tier 2) status and only recommended for selected clinical settings. In our view, this algorithm does not offer physicians and patients the appropriate selection of options to individualise and optimise care with a view to sustained control of blood glucose and reduction both of diabe…

Reversible self-assembly of metal chalcogenide/metal oxide nanostructures based on Pearson hardness.

2010

Nanotechnology has reached a stage of development where not individual nanoparticles but rather systems of greater complexity are the focus of concern. These complex structures incorporate two or more types of materials, an example of which is the formation of metal–semiconductor hybrids, which effectively combine the properties of both materials. The assembly of multicomponent nanoparticles from constituents with different optical, electrical, magnetic, and chemical properties can lead to novel functionalities that are independent of the individual components and may be tailored to fit a specific application. These applications include such far-reaching challenges as solar energy conversio…

Measurement of charged jet production cross sections and nuclear modification in p–Pb collisions at √sNN=5.02 TeV

2015

Charged jet production cross sections in p–Pb collisions at √sNN = 5.02 TeV measured with the ALICE detector at the LHC are presented. Using the anti-kT algorithm, jets have been reconstructed in the central rapidity region from charged particles with resolution parameters R = 0.2 and R = 0.4. The reconstructed jets have been corrected for detector effects and the underlying event background. To calculate the nuclear modification factor, RpPb, of charged jets in p–Pb collisions, a pp reference was constructed by scaling previously measured charged jet spectra at √s = 7 TeV. In the transverse momentum range 20 ≤ pT, ch jet ≤ 120 GeV/c, RpPb is found to be consistent with unity, indicating th…

MODIFICA SUPERFICIALE DI FILM DI POLY(ETILENE-co-ACIDO ACRILICO) CON NANOPARTICELLE DI SILICE ATTIVATA

2009

Zirconocene-Based Methods for the Preparation of BN-Indenes : Application to the Synthesis of 1,5-Dibora-4a,8a-diaza-1,2,3,5,6,7-hexaaryl-4,8-dimethy…

2017

A method for the preparation of 3-bora-9aza-indene heterocycles based on zirconocene mediated functionalization of the ortho-CH bonds of pyridines has been developed and used to make two such compounds. Unlike other methods, the boron center in these heterocycles remains functionalized with a chloride ligand and so the compounds can be further elaborated through halide abstraction and reduction. The utility of the method was further demonstrated by applying it towards the preparation of 1,5- dibora-4a,8a-diaza BN analogues of the intriguing hydrocarbon s-indacene starting from 2,5-dimethylpyrazine. Gram quantities of one such compound was prepared and fully characterized, and both experimen…