Search results for " mr"
showing 10 items of 495 documents
Gadolinium-chelating nanogels as MR contrast agents specifically targeting tumor cells
2014
Aims and objectives Methods and materials Results Conclusion Personal information References
Quantitative study of cardiac wall motion from cine-MRI using frequency-based optical flow methods
2010
The aim of this thesis is to study parietal desynchronisation of the left ventricle from conventional cine-MRI. The first part of our work consisted in the quantification of the left ventricle wall motion of the heart directly from conventional retrospective SSFP type cine-MRI sequences used in the study of cardiac function. The developed methods for measuring displacements within the images are frequency-based optical flow methods. These techniques seem to be particularly adapted to MRI specificities. We have demonstrated their robustness in the event of Rician noise and pixel intensity variations as a function of time. These variations are often associated with the through-plane motion of…
Neuronavigated-biopsy in the diagniosis of demyelinating pseudotumoral brain lesions. Case report.
2013
Introduction: Pseudotumoral-demyelinating lesions are typically characterized by severe difficulties in differential diagnosis from gliomas, metastatic tumors and abscesses. Marburg’s disease (MD) is an extremely rare and aggressive form of Mutiple Sclerosis (MS) with acute onset, rapid neurological deterioration, and poor prognosis. MRI images often show pseudotumoral lesions characterized by mild and focal or, sometimes, ring enhancement. Perhaps, radiological aspect can vary, making necessary hystopathological confirmation. Objectives: There is increasing interest in the role of surgical biopsy for a correct and early diagnosis of pseudotumoral demyelinating lesions. We report an histopa…
Three-dimensional architecture of the whole human soleus muscle in vivo
2018
Background Most data on the architecture of the human soleus muscle have been obtained from cadaveric dissection or two-dimensional ultrasound imaging. We present the first comprehensive, quantitative study on the three-dimensional anatomy of the human soleus muscle in vivo using diffusion tensor imaging (DTI) techniques. Methods We report three-dimensional fascicle lengths, pennation angles, fascicle curvatures, physiological cross-sectional areas and volumes in four compartments of the soleus at ankle joint angles of 69 ± 12° (plantarflexion, short muscle length; average ± SD across subjects) and 108 ± 7° (dorsiflexion, long muscle length) of six healthy young adults. Microdissection and…
MR imaging of entrapment neuropathies of the shoulder
2010
Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References
Interferon-alpha inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway.
2001
Hepatitis C virus (HCV) persists in the majority of infected individuals and is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. Chronic hepatitis C is currently treated with interferon (IFN)-α or with a combination of IFN-α and ribavirin. The availability of an HCV replicon system (Lohmann et al., Science 285, 110–113, 1999) allowed the investigation of the effects of IFN on genuine HCV replication in cultured cells. It is shown here that IFN-α inhibits subgenomic HCV RNA replication in HuH-7 human hepatoma cells. Immunofluorescence, Western blot and Northern blot analysis revealed that levels of both HCV protein and replicon RNA were reduced after treatme…
Ythdf is a N6‐methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila
2021
Abstract N6‐methyladenosine (m6A) regulates a variety of physiological processes through modulation of RNA metabolism. This modification is particularly enriched in the nervous system of several species, and its dysregulation has been associated with neurodevelopmental defects and neural dysfunctions. In Drosophila, loss of m6A alters fly behavior, albeit the underlying molecular mechanism and the role of m6A during nervous system development have remained elusive. Here we find that impairment of the m6A pathway leads to axonal overgrowth and misguidance at larval neuromuscular junctions as well as in the adult mushroom bodies. We identify Ythdf as the main m6A reader in the nervous system,…
Functional relevance and diagnostic utility of ROI-based and voxel-based diffusion-tensor imaging analyses in mild cognitive impairment
2007
DIFFERENT LOCATIONS OF ENDOMETRIOSIS IN 86 PATIENTS: A SINGLE- CENTRE STUDY.
2015
Endometriosis is an important gynecologic disorder defined as the presence of functional endometrial glands and stroma outside the uterine cavity. Prevalence of endometriosis is 6-10% in the general population, but rises to 35-50% in women with pelvic pain or infertility or both. The aim of this study was to retrospectively review the different locations of pelvic and extrapelvic endometriosis occurred in our Department during last 3 years.
Role of imaging in the preoperative assessment of pelvic and extrapelvic endometriosis: a pictorial essay
2015
Aims and objectives Methods and materials Results Conclusion Personal information References