Search results for " multiple"

showing 10 items of 903 documents

Surveillance of multidrug-resistant gram-negative bacilli in a neonatal intensive care unit: prominent role of cross transmission

2007

Background Multidrug-resistant gram-negative bacilli (MDRGN) are an important cause of nosocomial infections in neonatal intensive care units (NICUs). We conducted a 1-year prospective surveillance study in an NICU to assess the epidemiology of MDRGN among newborns and the relative importance of acquisition routes. Methods Neonates admitted at the NICU of the Dipartimento Materno-Infantile, University Hospital, Palermo, Italy, from January 7, 2003, to January 6, 2004, were included in the study. Colonization of patients with MDRGN was assessed by cultures of rectal swabs sampled twice a week. Pulsed-field gel electrophoresis was used to determine relatedness among MDRGN isolates. Extended-s…

Malemedicine.medical_specialtyPediatricsNeonatal intensive care unitEpidemiologymedicine.drug_classAntibioticsBreastfeedingMicrobial Sensitivity TestsEnterobacteriaceaeIntensive Care Units NeonatalIntensive careEpidemiologymedicineHumansProspective StudiesCross InfectionInfection ControlSurveillanceTransmission (medicine)business.industryHealth PolicyIncidence (epidemiology)Infant NewbornPublic Health Environmental and Occupational Healthneonatal intensive care unitDrug Resistance MultipleElectrophoresis Gel Pulsed-FieldInfectious DiseasesItalyFemaleGentamicinGram-Negative Bacterial InfectionsbusinessSentinel Surveillancemultidrug-resistant gram-negative bacillimedicine.drug
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Coincident vesical transitional cell carcinoma and prostatic carcinoma. Clinical features and treatment.

1986

Summary— Twenty-two patients with vesical urothelial carcinoma associated with prostatic carcinoma were reviewed. They represented 1.5% of the bladder and prostatic tumours treated in our department within a 12-year period from 1968 to 1979. Their management included several treatment policies, based on the separate assessment of each tumour variant. For non-infiltrating bladder tumours, transurethral tumour resection was combined with hormonal treatment, external radiotherapy or resection of the prostate depending on the stage of the prostatic tumour. Radical cystoprostatectomy was performed for two cases of infiltrating bladder tumour with well localised prostatic tumours. A conservative …

Malemedicine.medical_specialtyUrologymedicine.medical_treatmentTumor resectionUrologyCystoprostatectomyNeoplasms Multiple PrimaryProstatemedicineCarcinomaHumansNeoplasm InvasivenessStage (cooking)PathologicalAgedCarcinoma Transitional Cellbusiness.industryCancerProstatic NeoplasmsMiddle Agedmedicine.diseasePrognosismedicine.anatomical_structureTransitional cell carcinomaUrinary Bladder NeoplasmsbusinessBritish journal of urology
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An abdominal aortic aneurysm (AAA) in combination with duplication of the inferior vena cava (IVC), the right renal artery (RRA) and the right renal …

1990

Intra-abdominal abnormality of vessels may sometimes lead to complications. A case of the rare combination of an abdominal aortic aneurysm (AAA) at the origin of the inferior mesenteric a. with duplications of the inferior vena cava (IVC), the right renal a. (RRA) and the right renal v. (RRV) as well as absence of the left common iliac v. is reported.

Malemedicine.medical_specialtyVena Cava InferiorRight renalInferior vena cavaRenal VeinsPathology and Forensic MedicineRenal ArteryInternal medicineGene duplicationmedicineHumansAbnormalities MultipleRadiology Nuclear Medicine and imagingAorta Abdominalcardiovascular diseasesRight Renal ArteryAgedRight renal veinbusiness.industrymedicine.diseaseAbdominal aortic aneurysmAortic Aneurysmmedicine.veincardiovascular systemCardiologySurgeryAnatomybusinessSurgical and Radiologic Anatomy
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Pheochromocytoma in the Pediatric Age Group: The Prostate—An Unusual Location

1990

AbstractPheochromocytomas of the prostate are rare, with only 3 cases in adults reported in the literature. We present the case of an 8-year-old boy with a pheochromocytoma of the prostate and a second tumor in the region of the left internal iliac artery. (J. Urol., 144: 1219–1221, 1990)

Malemedicine.medical_specialtybusiness.industryUrologyProstatic NeoplasmsPediatric agePheochromocytomamedicine.diseaseIliac ArterySurgeryNeoplasms Multiple PrimaryPheochromocytomamedicine.anatomical_structureEl NiñoLeft internal iliac arteryProstateHypertensionHumansMedicineChildbusinessJournal of Urology
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High frequency of colorectal adenoma in patients with duodenal adenoma but without familial adenomatous polyposis

2004

Abstract Background Duodenal adenomas are extremely common in patients with familial adenomatous polyposis. However, it is uncertain whether patients with duodenal adenomas without familial adenomatous polyposis are at greater risk for colorectal neoplasia and, therefore, should routinely undergo surveillance colonoscopy. The aim of this study was to determine whether there is a correlation between non-papillary duodenal adenoma without familial adenomatous polyposis and colorectal adenoma. Methods Twenty-five patients with non-papillary duodenal adenomas without familial adenomatous polyposis, seen from January 1990 to April 2003, were retrospectively evaluated. Results Non-papillary duode…

Malemedicine.medical_specialtyendocrine system diseasesColorectal cancerBiopsyPopulationColonic PolypsColonoscopyColorectal adenomaGastroenterologyFamilial adenomatous polyposisNeoplasms Multiple PrimaryDuodenal AdenomaDuodenal NeoplasmsInternal medicineAdenoma VillousmedicineHumansRadiology Nuclear Medicine and imagingIntestinal MucosaeducationAgededucation.field_of_studymedicine.diagnostic_testbusiness.industryGastroenterologyPapillary AdenomaMiddle Agedmedicine.diseasedigestive system diseasesProctoscopystomatognathic diseasesCross-Sectional StudiesAdenomatous Polyposis ColiPopulation SurveillanceFemaleColorectal NeoplasmsbusinessGastrointestinal Endoscopy
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GDS score as screening tool to assess the risk of impact of chronic conditions and depression on quality of life in hospitalized elderly patients in …

2021

Aging of population is characterized by multiple chronic conditions in the same individual. Health-related quality of life (HR-QOL) reflects the multidimensional impact of chronic disease on population and it is increasingly analysed as outcomes. The aim of this study was the evaluation of the predictors of quality of life among elderly patients hospitalized in internal medicine ward, investigating the effect of comorbidities on health-related quality of life. Data collected in this cross-sectional study were analysed. Socio-demographic, clinical characteristics, disease distribution and quality of life by the 12-Item Short Form Health Survey (SF-12) were evaluated. Of 240 inpatients, subje…

Malemedicine.medical_specialtyfrail eldersMultivariate analysisCross-sectional studyFrail ElderlyPopulationHospital DepartmentsObservational StudyPatient Health Questionnairebehavioral disciplines and activities500003 medical and health sciences0302 clinical medicineQuality of lifeNeoplasmsInternal medicineDiabetes MellitusInternal MedicineHumansMedicine030212 general & internal medicineeducationDepression (differential diagnoses)Agededucation.field_of_studyDepressionbusiness.industryLiver DiseasesSocial Supportmultiple chronic conditionsGeneral MedicineMental healthhumanitiesHospitalizationPatient Health Questionnairedepression frail elders multiple chronic conditions quality of life Aged Cross-Sectional Studies Depression Diabetes Mellitus Female Frail Elderly Hospital Departments Humans Internal Medicine Liver Diseases MaleMultiple Chronic Conditions Neoplasms Social Support Hospitalization Patient Health Questionnaire Quality of LifeCross-Sectional Studiesquality of life030220 oncology & carcinogenesisFemaleGeriatric Depression ScalebusinessResearch Article
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The hypothetical role of congenital hypotonia in the development of early coronoid hyperplasia

2012

Abstract Background Coronoid hyperplasia (CH) is an abnormal bony elongation of a histologically normal coronoid process. Its definitive cause remains unknown. Objectives To analyze the possible implication of congenital hypotonia in the pathogenesis of early coronoid overgrowth. Patients and methods Two infants with congenital hypotonia were evaluated for limited mouth aperture. Bilateral CH was diagnosed. Transoral coronoidectomy was followed by an early dynamic physiotherapy program. Results Significant improvement of maximum interincisal opening was achieved. The review of the scientific literature proved the diagnosis of CH in the infant age group is extremely unusual and the etiology …

Malemedicine.medical_specialtymedicine.medical_treatmentMandibleAspiration pneumoniaTracheostomySwallowingmedicineHumansAbnormalities MultipleRange of Motion ArticularArthrogryposisGastrostomyHyperplasiabusiness.industryInfantHyperplasiamedicine.diseaseHematologic DiseasesMusculoskeletal ManipulationsGastrostomySurgerymedicine.anatomical_structureVestibular DiseasesOtorhinolaryngologyFaceMasticatory MusclesFailure to thriveSuprahyoid musclesEtiologyMuscle HypotoniaSurgeryOral Surgerymedicine.symptomChokingbusinessFollow-Up StudiesJournal of Cranio-Maxillofacial Surgery
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Monochorionic twin pregnancy: screening, pathogenesis of complications and management in the era of microinvasive fetal surgery

2010

Objective The management of monochorionic (MC) twin pregnancies varies in different medical centers. This paper compares screening methods to predict the complications of the MC twin pregnancy and different treatment methods. Methods We performed a literature search without language restriction in Cochrane library and PubMed (1970-2009). Case series and cohort screening studies, pathogenesis and management of complications of MC pregnancy were included. Results Elevated risk for intrauterine fetal death (IUFD) and twin-to-twin transfusion syndrome (TTTS) can be detected sonographically. Monitoring of MC pregnancies at increased risk and regular training sessions for the operating team combi…

Malemedicine.medical_specialtymedicine.medical_treatmentPrenatal diagnosisModels BiologicalPregnancyPrenatal DiagnosismedicineHumansAmnionNeonatologySurvival rateTwin PregnancyUltrasonographyFetal TherapiesPregnancyFetal Growth RetardationLaser CoagulationFetal surgeryObstetricsbusiness.industryInfant NewbornObstetrics and GynecologyChorionFetofetal TransfusionTwins Monozygoticmedicine.diseasePregnancy ComplicationsPediatrics Perinatology and Child HealthFemaleMonochorionic twinsPregnancy MultiplebusinessLaser coagulationJournal of Perinatal Medicine
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Clinical and biochemical determinants of the extent of liver steatosis in type 2 diabetes mellitus

2015

Objective Nonalcoholic fatty liver disease is very frequent in both type 2 diabetes mellitus (T2DM) and the metabolic syndrome (MS), which share clinical and metabolic characteristics. Whether and to which extent these characteristics can predict the degree of liver steatosis are not entirely clear. Patients and methods We determined liver fat (divided into four classes) by standard sonographic images, and clinical and biochemical variables, in 60 consecutive patients with T2DM and with features of the MS. We examined both simple and multiple correlations between the degree of liver steatosis and the variables measured. Results Increased liver fat (defined as >5% of liver mass) was detec…

Malenonalcoholic fatty liver diseasemedicine.medical_specialtytype 2 diabetes mellitusmedicine.medical_treatmentSettore MED/50 - Scienze Tecniche Mediche ApplicateGastroenterologyleptinliver steatosispredictive modelInsulin resistanceNon-alcoholic Fatty Liver DiseaseInternal medicineinsulin resistanceNonalcoholic fatty liver diseasemedicineHumansInsulinAdiposityAgedUltrasonographyvisceral adiposityGlycated HemoglobinMetabolic SyndromeSettore SECS-S/06 - Metodi mat. dell'economia e Scienze Attuariali e FinanziarieModels StatisticalAnthropometryHepatologybusiness.industryInsulinHemoglobin A1c; insulin resistance; leptin; liver steatosis; metabolic control; multiple regression analysis; nonalcoholic fatty liver disease; predictive model; type 2 diabetes mellitus; visceral adiposity;GastroenterologyType 2 Diabetes MellitusHemoglobin A1c; insulin resistance; leptin; liver steatosis; metabolic control; multiple regression analysis; nonalcoholic fatty liver disease; predictive model; type 2 diabetes mellitus; visceral adiposity; Gastroenterology; Hepatologymetabolic controlmultiple regression analysisMiddle AgedHepatologymedicine.diseaseEndocrinologyDiabetes Mellitus Type 2Hemoglobin A1cMetabolic control analysisFemaleWaist CircumferenceSteatosisMetabolic syndromebusinesshemoglobin A1c leptin liver steatosis metabolic control multiple regression analysis nonalcoholic fatty liver disease insulin resistance predictive model type 2 diabetes mellitus visceral adiposity
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Injectable Versus Oral First-Line Disease-Modifying Therapies: Results from the Italian MS Register

2021

AbstractThe current study aims to compare injectable and oral first-line disease-modifying therapies (DMTs) for time to first relapse, time to confirmed disability progression (CDP), and time to discontinuation using a cohort of relapsing remitting multiple sclerosis (RRMS) patients, with data extracted from the Italian MS Register. This multicenter, observational, retrospectively acquired, and propensity-adjusted cohort study utilized RRMS-naïve patients from the Italian MS Register who started either injectable or oral first-line DMTs between January 1, 2010, and December 31, 2017, to evaluate the impact on disability outcomes in patients. Enrolled patients were divided into two groups, n…

Maleoral DMTsoral DMTAdministration OralDiseaseRelapsing-RemittingCohort Studies0302 clinical medicineImmunologicinjectable DMTPharmacology (medical)030212 general & internal medicineRegistriesSubcutaneousMiddle AgedItalyEDSS score; injectable DMTs; Multiple sclerosis; oral DMTs; real-world setting; Adjuvants Immunologic; Administration Oral; Adult; Cohort Studies; Female; Follow-Up Studies; Glatiramer Acetate; Humans; Immunologic Factors; Injections Subcutaneous; Interferon-beta; Italy; Male; Middle Aged; Multiple Sclerosis Relapsing-Remitting; Retrospective Studies; RegistriesAdministrationCohortSettore MED/26 - NeurologiaOriginal ArticleFemaleNeurosurgeryCohort studyOralAdultmedicine.medical_specialtyEDSS scoreInjections SubcutaneousLower riskInjectionsMultiple sclerosis03 medical and health sciencesMultiple Sclerosis Relapsing-RemittingAdjuvants ImmunologicInternal medicinereal-world settingmedicineHumansImmunologic FactorsMultiple sclerosiAdjuvantsinjectable DMTsRetrospective StudiesPharmacologybusiness.industryMultiple sclerosisGlatiramer AcetateInterferon-betamedicine.diseaseDiscontinuationObservational studyNeurology (clinical)business030217 neurology & neurosurgeryFollow-Up Studies
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