Search results for " nanocomposite"

showing 10 items of 199 documents

Pyrazole[3,4-d]pyrimidine derivatives loaded into halloysite as potential CDK inhibitors

2021

Uncontrolled cell proliferation is a hallmark of cancer as a result of rapid and deregulated progression through the cell cycle. The inhibition of cyclin-dependent kinases (CDKs) activities is a promising therapeutic strategy to block cell cycle of tumor cells. In this work we reported a new example of nanocomposites based on halloysite nanotubes (HNTs)/pyrazolo[3,4-d]pyrimidine derivatives (Si306 and Si113) as anticancer agents and CDK inhibitors. HNTs/Si306 and HNTs/Si113 nanocomposites were synthesized and characterized. The release kinetics were also investigated. Antitumoral activity was evaluated on three cancer cell lines (HeLa, MDA-MB-231 and HCT116) and the effects on cell cycle ar…

Cell cycle checkpointPyrimidinePharmaceutical Science02 engineering and technologyCDK inhibitors; Halloysite; Nanocomposites; Pyrazolo[34-d]pyrimidine derivatives; Cell Cycle Checkpoints; Cell Line Tumor; Clay; Humans; Pyrazoles; PyrimidinesPyrazolo[34-d]pyrimidine derivativesPyrazole030226 pharmacology & pharmacyCell LineNanocompositesHeLa03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCyclin-dependent kinaseCell Line TumorPyrazolo[3HumansSettore BIO/06 - Anatomia Comparata E CitologiaSettore CHIM/02 - Chimica FisicaTumorbiologyChemistryKinaseCell growth4-d]pyrimidine derivativesHalloysiteSettore CHIM/06 - Chimica OrganicaCell Cycle CheckpointsCell cycle021001 nanoscience & nanotechnologybiology.organism_classificationSettore BIO/18 - GeneticaPyrimidinesSettore CHIM/03 - Chimica Generale E Inorganicabiology.proteinCancer researchClayPyrazoles0210 nano-technologyCDK inhibitors
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Degradation of PA 11 nanocomposites: the chemical point of view

2016

We aim to investigate both thermal degradation processes (non oxidative and oxidative) occurring in PA11 nanocomposites and establish the eventual contribution of organo nanoclay modifier on degradation mechanisms.

DegradationPA 11 nanocomposites
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Investigation of AC Electrical Properties of MXene-PCL Nanocomposites for Application in Small and Medium Power Generation

2021

The paper examined Ti3C2Tx MXene (T—OH, Cl or F), which is prepared by etching a layered ternary carbide Ti3AlC2 (312 MAX-phase) precursor and deposited on a polycaprolactone (PCL) electrospun membrane (MXene-PCL nanocomposite). X-ray Diffraction analysis (XRD) and Scanning Electron Microscopy (SEM) indicates that the obtained material is pure Ti3C2 MXene. SEM of the PCL-MXene composite demonstrate random Ti3C2 distribution over the nanoporous membrane. Results of capacitance, inductance, and phase shift angle studies of the MXene-PCL nanocomposite are presented. It was found that the frequency dependence of the capacitance exhibited a clear sharp minima in the frequency range of 50 Hz to o…

DiffractionTechnologyControl and OptimizationNanocompositeMaterials scienceRenewable Energy Sustainability and the EnvironmentScanning electron microscopeTEnergy Engineering and Power TechnologyMXene-PCL nanocompositesElectronflexible electronicsCapacitanceMolecular physicsInductanceAmplitudeelectrical propertiesElectrical and Electronic EngineeringMXeneTernary operationEngineering (miscellaneous)small and medium power generationEnergy (miscellaneous)Energies
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Sol-gel synthesis and photocatalytic activity of ZnO-SnO2 nanocomposites

2014

Abstract ZnO–SnO 2 nanocomposites were synthesized by a facile sol–gel synthesis route and characterized through X-ray diffraction, BET specific surface area analysis, UV–vis diffuse reflectance spectroscopy, photoluminescence spectroscopy, X-ray photoelectron spectroscopy, scanning electron microscopy, transmission electron microscopy. The photocatalytic activity of the samples was tested using the degradation of 4-nitrophenol under UV light as model reaction. The ZnO/SnO 2 molar ratio was varied in order to study its influence on the photoefficiency of the samples. The ZnO–SnO 2 nanocomposites showed higher photoactivity than the pure oxides and in particular the sample with ZnO/SnO 2 mol…

Diffuse reflectance infrared fourier transformChemistryScanning electron microscopeProcess Chemistry and TechnologyAnalytical chemistryHeterojunctionCatalysisZnO-SnO2 nanocompositePhotocatalysiX-ray photoelectron spectroscopyHeterojunction effectSpecific surface areaPhotocatalysisPhotocatalysis; ZnO-SnO2 nanocomposites; Sol-gel method; Heterojunction effectSettore CHIM/07 - Fondamenti Chimici Delle TecnologiePhysical and Theoretical ChemistrySpectroscopySol-gel methodSol-gel
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Dense drug-eluting biodegradable Fe-Ag nanocomposites

2021

Abstract Biodegradable metals in orthopedics are aimed to eliminate secondary the surgical intervention for implant removal, and thus improve patient compliance, reduce surgery costs and the risk of infections. In addition, biodegradable implants could be loaded with different drugs to prevent the growth of pathogens and the development of bone infections, kill remaining cancer cells after tumor resection or stimulate bone regeneration. However, drugs undergo thermal decomposition under the conditions of conventional metal fabrication processes. In this work, we describe the fabrication of a dense drug-eluting biodegradable Fe-Ag nanocomposite containing 10 vol% of Ag and loaded with the an…

DrugMaterials scienceLocal drug deliverymedia_common.quotation_subjectCold sinteringTumor resection02 engineering and technology010402 general chemistry01 natural sciencesImplant removalBone biomaterialsDrug-eluting metalsmedicineGeneral Materials ScienceBone regenerationPatient complianceMaterials of engineering and construction. Mechanics of materialsmedia_commonNanocompositeMechanical EngineeringBiodegradable implants021001 nanoscience & nanotechnology0104 chemical sciencesFe-Ag nanocompositesMechanics of MaterialsTA401-492VancomycinBiodegradable metals0210 nano-technologyBiomedical engineeringmedicine.drugMaterials & Design
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Durability of advanced nanocomposites based on polyethylene oxide and nanodiamonds

2016

Nanodiamonds nanoparticles (NDs) are amongst the most promising materials for multifunctional nanocomposites for various applications

Durability advanced nanocomposites polyethylene oxide nanodiamonds
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Non-isothermal elongational flow of polymer nanocomposites

2018

The elongational flow is a very important flow involved in important processing operations, like spinning, film blowing, etc. In these processing operations, the molten polymer is subject to the elongational flow and at the same time is cooled (non-isothermal elongational flow). The response to the non-isothermal elongational flow of the melt is then the critical parameter to process the polymer in these processing operations. MS (melt strength) and BSR (breaking stretching ratio) are to two values measured during the non-isothermal flow and depend mainly on the molecular structure of the polymer. In biphasic systems, the adhesion and the shape of the dispersed particles play a very importa…

Elongational flow polymer nanocomposites
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Preparation of functionalized-MW-CNTs/Polyolefin nanocomposites and analysis of their physical properties

2010

FUNCTIONALIZED CNTPOLYMER NANOCOMPOSITES
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Impact of nanoparticles on the environmental sustainability of polymer nanocomposites based on bioplastics or recycled plastics – A review of life-cy…

2022

Adding nanoparticles to a host polymer can lead to performance improvements that can be twice as beneficial to the environment: first, sustainable nanocomposites based on bioplastics or recycled plastics could replace ubiquitous petroleum-based polymers; second, substantial plastic saving could be achieved by profiting from the superior specific properties of the nanocomposites. Nevertheless, the inherent environmental burden of nanoparticles can compromise the expected benefits. Here we address the controversial issue of the environmental sustainability of “green” polymer nanocomposites based on bioplastics and recycled plastics. A critical review of life-cycle assessment studies regarding…

Life-cycle assessmentNanocompositeRenewable Energy Sustainability and the EnvironmentStrategy and ManagementSustainabilityBioplasticsRecycled plasticNanoparticlesNanocompositeLife-cycle assessmentIndustrial and Manufacturing EngineeringBioplasticNanoparticleBioplastics; Life-cycle assessment; Nanocomposite; Nanoparticles; Recycled plastic; SustainabilitySustainabilityRecycled plasticNanoparticlesGeneral Environmental ScienceBioplastics
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Thermo-oxidative stabilization of poly(lactic acid)-based nanocomposites through the incorporation of clay with in-built antioxidant activity

2017

In this work, an innovative approach to overcome the issue of the poor thermo-oxidative stability of polymer/clay nanocomposites is proposed. Specifically, biodegradable poly(lactic acid) (PLA)-based nanocomposites, containing organo-modified clay with in-built antioxidant activity, were prepared. Through a two-step chemical protocol, a hindered phenol antioxidant was chemically linked to the ammonium quaternary salt which was then intercalated between the clay platelets [(AO)OM-Mt]. The nanocomposites were characterized and their thermo-oxidative stability during melt processing and under long-term thermal test conditions was investigated. PLA nanocomposites containing the (AO)OM-Mt showed…

Materials Chemistry2506 Metals and AlloysAntioxidantMaterials sciencePolymers and Plasticsmedicine.medical_treatmentSurfaces Coatings and FilmSalt (chemistry)02 engineering and technologybio-based nanocomposites; montmorillonite; poly(lactic acid) (PLA); thermo-oxidative stability; Chemistry (all); Surfaces Coatings and Films; Polymers and Plastics; Materials Chemistry; 2506; Metals and Alloysmontmorillonite010402 general chemistry01 natural sciencescomplex mixturesCoatings and Filmschemistry.chemical_compoundPolylactic acidpoly(lactic acid) (PLA)medicineMaterials ChemistryOrganic chemistrythermo-oxidative stabilitychemistry.chemical_classificationPolymers and PlasticNanocompositebio-based nanocompositesChemistry (all)Metals and AlloysGeneral ChemistryPolymer021001 nanoscience & nanotechnologybio-based nanocomposite0104 chemical sciencesSurfaces Coatings and FilmsLactic acidSurfacesMontmorillonitechemistryChemical engineering25060210 nano-technologyDispersion (chemistry)
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