Search results for " non"
showing 10 items of 5003 documents
The role of noise on the steady state distributions of phytoplankton populations
2016
The spatio-temporal behaviour of total chlorophyll concentration is investigated in the middle of the Tyrrhenian Sea by using a stochastic approach. The study is based on a reaction-diffusion-taxis model, which is used to analyse the dynamics of five phytoplankton groups, responsible for about 80% of the total chlorophyll a inside the euphotic zone of the water column. The analysis is performed by considering: (i) the intraspecific competition of the phytoplanktonic groups for limiting factors, i.e. light intensity and nutrient concentration, (ii) the seasonal changes of environmental variables, and (iii) the random fluctuations of the components of the velocity field and temperature. Speci…
Pedotransfer functions for estimating soil water retention curve of Sicilian soils
2019
Pedotransfer functions (PTFs) make use of routinely surveyed soil data to estimate soil properties but their application to soils different from those used for their development can yield inaccurate estimates. This investigation aimed at evaluating the water retention prediction accuracy of eight existing PTFs using a database of 217 Sicilian soils exploring 11 USDA textural classes. PTFs performance was assessed by root mean square differences (RMSD) and average differences (AD) between estimated and measured data. Extended Nonlinear Regression (ENR) technique was adopted to recalibrate or develop four new PTFs and Wind’s evaporation method was applied to validate the effectiveness of the …
Finite-time stability and stabilisation for a class of nonlinear systems with time-varying delay
2014
This paper is concerned with the problems of finite-time stability FTS and finite-time stabilisation for a class of nonlinear systems with time-varying delay, which can be represented by Takagi–Sugeno fuzzy system. Some new delay-dependent FTS conditions are provided and applied to the design problem of finite-time fuzzy controllers. First, based on an integral inequality and a fuzzy Lyapunov–Krasovskii functional, a delay-dependent FTS criterion is proposed for open-loop fuzzy system by introducing some free fuzzy weighting matrices, which are less conservative than other existing ones. Then, the parallel distributed compensation controller is designed to ensure FTS of the time-delay fuzzy…
High-temperature in-process inspection followed by 96-h robotic inspection of intentionally manufactured hydrogen crack in multi-pass robotic welding
2021
Abstract This investigation introduces two new techniques to quantitatively address the challenging problem of understanding Hydrogen Induced Cracking (HIC) in welding processes. The first technique is a novel procedure to create a known and controlled HIC in a welded sample. The second is an in-process monitoring technique to measure the initial formation and subsequent growth of the HIC in a multi-pass weld whilst being compatible with the high temperatures associated with the welding process. The HIC was initiated using a localised quenching method of the weld and its character was verified using both macrograph and microscopic investigations. During HIC initiation and growth, the sample…
Assessing the accuracy of industrial robots through metrology for the enhancement of automated non-destructive testing
2016
This work presents the study of the accuracy of an industrial robot KR5 arc HW, used to perform quality inspections of components with complex shapes. Metrology techniques such as laser tracking and large volume photogrammetry were deployed to quantify both pose and dynamic path accuracies of the robot in accordance with ISO 9283:1998. The overall positioning pose inaccuracy of the robot is found to be almost 1 mm and path inaccuracy at 100% of the robot rated velocity is 4.5 mm. The maximum pose orientation inaccuracy is found to be 14 degrees and the maximum path orientation inaccuracy is 5 degrees. Despite of the significant maximum inaccuracies, uncertainty of a robotic scanning applica…
Comparison of fully non-stationary artificial accelerogram generation methods in reproducing seismicity at a given site
2020
Abstract Seismic input modelling is a crucial step when Non-Linear Time-History Analyses (NLTHAs) are performed, the seismic response of structures being highly responsive to the input employed. When natural accelerograms able to represent local seismicity are not available, the use of generated accelerograms is an efficient solution for input modelling. The aim of the present paper is to compare four methods for generating fully non-stationary artificial accelerograms on the basis of a target spectrum, identified using seven recorded accelerograms registered in the neighbourhood of the construction site during a single event, assumed as target accelerograms. For each method, seven accelero…
Two-qubit entanglement dynamics for two different non-Markovian environments
2009
We study the time behavior of entanglement between two noninteracting qubits each immersed in its own environment for two different non-Markovian conditions: a high-$Q$ cavity slightly off-resonant with the qubit transition frequency and a nonperfect photonic band-gap, respectively. We find that revivals and retardation of entanglement loss may occur by adjusting the cavity-qubit detuning, in the first case, while partial entanglement trapping occurs in non-ideal photonic-band gap.
2,3-Dihydrobenzofuran privileged structures as new bioinspired lead compounds for the design of mPGES-1 inhibitors
2016
International audience; 2,3-Dihydrobenzofurans are proposed as privileged structures and used as chemical platform to design small compound libraries. By combining molecular docking calculations and experimental verification of biochemical interference, we selected some potential inhibitors of microsomal prostaglandin E2 synthase (mPGES)-1. Starting from low affinity natural product 1, by our combined approach we identified the compounds 19 and 20 with biological activity in the low micromolar range. Our data suggest that the 2,3-dihydrobenzofuran derivatives might be suitable bioinspired lead compounds for development of new generation mPGES-1 inhibitors with increased affinity.
Retinoic Acid affects Lung Adenocarcinoma growth by inducing differentiation via GATA6 activation and EGFR and Wnt inhibition
2016
AbstractA fundamental task in cancer research aims at the identification of new pharmacological therapies that can affect tumor growth. Differentiation therapy might exploit this function not only for hematological diseases, such as acute promyelocytic leukemia (APML) but also for epithelial tumors, including lung cancer. Here we show that Retinoic Acid (RA) arrests in vitro and in vivo the growth of Tyrosine Kinase Inhibitors (TKI) resistant Non Small Cell Lung Cancer (NSCLC). In particular, we found that RA induces G0/G1 cell cycle arrest in TKI resistant NSCLC cells and activates terminal differentiation programs by modulating the expression of GATA6, a key transcription factor involved …
Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus.
2020
Adult hippocampal neurogenesis was originally discovered in rodents. Subsequent studies identified the adult neural stem cells and found important links between adult neurogenesis and plasticity, behavior, and disease. However, whether new neurons are produced in the human dentate gyrus (DG) during healthy aging is still debated. We and others readily observe proliferating neural progenitors in the infant hippocampus near immature cells expressing doublecortin (DCX), but the number of such cells decreases in children and few, if any, are present in adults. Recent investigations using dual antigen retrieval find many cells stained by DCX antibodies in adult human DG. This has been interprete…