Search results for " obesity"

showing 10 items of 504 documents

Glucagon-like peptide-2 and mouse intestinal adaptation to a high-fat diet.

2013

Endogenous glucagon-like peptide-2 (GLP2) is a key mediator of refeeding-induced and resection-induced intestinal adaptive growth. This study investigated the potential role of GLP2 in mediating the mucosal responses to a chronic high-fat diet (HFD). In this view, the murine small intestine adaptive response to a HFD was analyzed and a possible involvement of endogenous GLP2 was verified using GLP2 (3–33) as GLP2 receptor (GLP2R) antagonist. In comparison with animals fed a standard diet, mice fed a HFD for 14 weeks exhibited an increase in crypt–villus mean height (duodenum, 27.5±3.0%; jejunum, 36.5±2.9%;P<0.01), in the cell number per villus (duodenum, 28.4±2.2%; jejunum, 32.0±2.9%;P&l…

Malemedicine.medical_specialtyDuodenumEndocrinology Diabetes and MetabolismEndogenyBiologyDiet High-Fatdigestive systemJejunumMiceEndocrinologyInternal medicineIntestine SmallmedicineGlucagon-Like Peptide 2Receptors GlucagonAnimalsMolecular Targeted TherapyObesityIntestinal MucosaReceptorCell ProliferationCell growthdigestive oral and skin physiologyGLP2 receptor expression intestinal morphometry obesity intestinal adaptationGlucagon-like peptide-2Adaptation PhysiologicalSmall intestinePeptide FragmentsUp-RegulationMice Inbred C57BLEndocrinologymedicine.anatomical_structureJejunumKi-67 AntigenDuodenumGlucagon-Like Peptide-2 ReceptorAnti-Obesity AgentsGlucagon-Like Peptide-2 ReceptorSignal TransductionThe Journal of endocrinology
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Left ventricular diastolic and systolic function in normotensive obese subjects: influence of degree and duration of obesity.

1992

The present study was carried out to evaluate systolic and diastolic parameters in overweight and moderately obese, but otherwise healthy subjects, and in a lean control group, to determine whether degree and duration of obesity can influence left ventricular function. A total of 27 subjects, 17 overweight or with moderate obesity and 10 lean, healthy subjects were included. Patients were divided into three groups according to their body mass index (BMI) and to Garrow's criteria as follows: lean control group (BMI less than 25 kg.m-2); overweight subjects (BMI from 25 to 30 kg.m-2); moderately obese subjects (BMI greater than 30 less than 40 kg.m-2). Systolic and diastolic parameters were m…

Malemedicine.medical_specialtyMean arterial pressureSettore MED/09 - Medicina InternaTime FactorsSystoleDiastoleBlood PressureOverweightVentricular Function LeftRadionuclide angiographyDiastoleInternal medicinemedicineHumansObesitySystoleEjection fractionmedicine.diagnostic_testbusiness.industryBody WeightInfant Newbornnutritional and metabolic diseasesStroke VolumeStroke volumeMiddle AgedSettore MED/11 - Malattie Dell'Apparato CardiovascolareEndocrinologyLeft ventricular function Systolic function diastolic function peak filling rate obesity radionuclide angiography.CardiologyRegression AnalysisFemalemedicine.symptomCardiology and Cardiovascular MedicinebusinessBody mass indexEuropean heart journal
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Home-exercise Childhood Obesity Intervention: A Randomized Clinical Trial Comparing Print Versus Web-based (Move It) Platforms.

2018

Abstract Purpose To compare the impact of adhering to a Mediterranean diet plus mixed physical exercise program (Move-It) implemented by means of printed instructions or via a web-platform (with or without e-mail support) on body composition, physical fitness, and blood pressure. Design and Methods Randomized clinical trial. Fifty-two overweight or obese Spanish children and adolescents were randomly assigned to the print-based (n = 18), Move-It (n = 18), or Move-It plus support (n = 16) intervention groups. Two-way mixed ANOVA tests were used to compare any changes between the groups in terms of percentage body fat, physical fitness (VO2peak), handgrip strength, and systolic and diastolic …

Malemedicine.medical_specialtyPediatric ObesityAdolescentPhysical fitnessPhysical exerciseOverweightPediatricsBody fat percentageChildhood obesitylaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled trialWeight losslaw030225 pediatricsWeight LossmedicineHumans030212 general & internal medicineChildAnalysis of Variancebusiness.industryResistance Trainingmedicine.diseaseObesityHome Care ServicesExercise TherapyWeight Reduction ProgramsTreatment OutcomeSpainPhysical therapyFemalemedicine.symptombusinessJournal of pediatric nursing
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Relationship between body composition and vertical ground reaction forces in obese children when walking.

2016

Abstract Background Obesity is now a serious worldwide challenge, especially in children. This condition can cause a number of different health problems, including musculoskeletal disorders, some of which are due to mechanical stress caused by excess body weight. The aim of this study was to determine the association between body composition and the vertical ground reaction force produced during walking in obese children. Methods Sixteen children participated in the study, six females and ten males [11.5 (1.2) years old, 69.8 (15.5) kg, 1.56 (0.09) m, and 28.36 (3.74) kg/m 2 of body mass index (BMI)]. Total weight, lean mass and fat mass were measured by dual-energy X-ray absorptiometry and…

Malemedicine.medical_specialtyPediatric ObesityPopulationBiophysics030209 endocrinology & metabolismWalkingBody Mass Index03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationAbsorptiometry PhotonLinear regressionmedicineHumansOrthopedics and Sports MedicineForce platform030212 general & internal medicineGround reaction forceeducationChildExerciseeducation.field_of_studybusiness.industryBody WeightRegression analysismedicine.diseaseObesityPhysical therapyLean body massBody CompositionFemalebusinessBody mass indexClinical biomechanics (Bristol, Avon)
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Differences in intermittent postural control between normal-weight and obese children.

2016

Abstract Aim The main objective of this study was to determine differences in postural control between obese and non-obese children. Methods The study design was cross-sectional, prospective, between-subjects. Postural control variables were obtained from a group of obese children and a normal-weight control group under two different postural conditions: bipedal standing position with eyes open and bipedal standing with eyes closed. Variables were obtained for each balance condition using time domain and sway-density plot analysis of the center of pressure signals acquired by means of a force plate. Results Pairwise comparisons revealed significant differences between obese and normal-weigh…

Malemedicine.medical_specialtyPediatric ObesityTime FactorsAdolescentCross-sectional studyPostureBiophysics030209 endocrinology & metabolismPostural controlPassive control03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationCenter of pressure (terrestrial locomotion)medicinePostural BalanceHumansOrthopedics and Sports MedicineProspective StudiesProspective cohort studyChildPostural Balancebusiness.industryRehabilitationBody WeightCross-Sectional StudiesNormal weightSensation DisordersPhysical therapyReflexFemalebusiness030217 neurology & neurosurgeryGaitposture
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Fast-food consumption and body mass index in children and adolescents: an international cross-sectional study.

2014

OBJECTIVE: To investigate whether reported fast-food consumption over the previous year is associated with higher childhood or adolescent body mass index (BMI). DESIGN: Secondary analysis from a multicentre, multicountry cross-sectional study (International Study of Asthma and Allergies in Children (ISAAC) Phase Three). SUBJECTS AND METHODS: Parents/guardians of children aged 6-7 completed questionnaires which included questions about their children's asthma and allergies, fast-food consumption, height and weight. Adolescents aged 13-14 completed the same questionnaire. The questionnaire asked 'In the past 12 months, how often on average did you (your child) eat fast-food/burgers?' The resp…

Malemedicine.medical_specialtyPediatricsAdolescentCross-sectional studyInfants AlimentacióAdolescentsGlobal HealthChildhood obesityBody Mass IndexChildhood overweightVery frequentBMIRisk FactorsEpidemiologymedicineHumans1724Obesity1506Childhood obesityChildNutricióAsthmabusiness.industryResearchConfounding1699PaediatricsGeneral MedicineFeeding Behaviormedicine.diseaseObesitySalut pública1692Cross-Sectional StudiesPopulation SurveillanceInternationalFast FoodsFast food consumptionFemaleAlimentsMorbidity1714businessBody mass indexInfants1719Follow-Up StudiesBMJ open
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Comorbidity between obesity and attention deficit/hyperactivity disorder: Population study with 13–15-year-olds

2006

Objective: This study analyzes whether obese children have a higher risk of attention deficit/hyperactivity “characteristics” (AD/HD) than do children with other nutritional states. Method: This study included 35,403 participants from 486 community schools. They completed the AD/HD scale of the Strengths and Difficulties Questionnaire (SDQ) and were weighed and measured. 2879 of the participants were obese and 78 were morbidly obese (BMI >40). Results: A discrete, nonsignificant, increment was found in the AD/HD characteristics of male participants with morbid obesity, as compared with the other nutritional states. Among morbidly obese females, the prevalence of AD/HD characteristics was sl…

Malemedicine.medical_specialtyPediatricsAdolescentmedia_common.quotation_subjectComorbidityOverweightMorbid obesityRisk FactorsmedicineHumansAttention deficit hyperactivity disorderObesityPsychiatrymedia_commonSelection biasStrengths and Difficulties Questionnairemedicine.diseaseComorbidityObesityPsychiatry and Mental healthAttention Deficit Disorder with HyperactivitySpainPopulation studyFemalemedicine.symptomPsychologyInternational Journal of Eating Disorders
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Adjusted population attributable fractions and preventable potential of risk factors for childhood obesity.

2007

AbstractObjectiveA number of individual risk factors for childhood obesity have been identified, but only some of these are amenable to prevention. To assess the amount of cases in a general population attributable to these risk factors, adjusted population-attributable fractions were estimated.DesignCross-sectional study.SettingObligatory school entry examination in 2001/2002 in six Bavarian communities (Germany).Subjects5472 children at age 5–6 years.MeasuresAnthropometric measures were ascertained by public health nurses, and measures concerning sociodemographics, lifestyle and child behaviour such as child's daily meal frequency were obtained with self-administered parental questionnair…

Malemedicine.medical_specialtyPediatricsCross-sectional studyPopulationMedicine (miscellaneous)Child BehaviorLogistic regressionChildhood obesityBody Mass IndexRisk FactorsGermanySurveys and QuestionnairesPrevalenceMedicineHumansObesityeducationChildExerciseLife Styleeducation.field_of_studyNutrition and DieteticsAnthropometrybusiness.industryPublic healthSmokingPublic Health Environmental and Occupational HealthFeeding BehaviorAnthropometrymedicine.diseaseObesityInfant FormulaCross-Sectional StudiesLogistic ModelsChild PreschoolFemaleTelevisionPublic HealthbusinessChild Nutritional Physiological PhenomenaBody mass indexDemographyPublic health nutrition
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Visceral obesity and metabolic syndrome: two faces of the same medal?

2009

In this review, we have analyzed the role of visceral obesity in the occurrence of metabolic syndrome (MetS). MetS is a common metabolic disorder that has been related recently to the increasing prevalence of obesity. The disorder is defined in various ways, but in the near future a new definition(s) should be applicable worldwide. The pathophysiology has been largely attributed, in the past years, to insulin resistance, although several epidemiological and pathophysiological data now indicate visceral obesity as a main factor in the occurrence of all the components of MetS. In view of this, relationships among visceral obesity, free fatty acids, dyslipidemia and insulin resistance have bee…

Malemedicine.medical_specialtySettore MED/09 - Medicina InternaAdipokineFatty Acids NonesterifiedBioinformaticsInsulin resistanceAdipokinesInternal medicineEpidemiologyInternal MedicineMedicineHumansDyslipidemiasMetabolic SyndromeAdiponectinbusiness.industryMetabolic disordermedicine.diseaseObesityEndocrinologyObesity AbdominalEmergency MedicineFemaleAdiponectinMetabolic syndromeInsulin ResistancebusinessDyslipidemiaMetabolic syndrome - Visceral obesity - Adipocytokines - AdiponectinInternal and emergency medicine
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Non-alcoholic fatty liver disease: Severity of fibrosis and its relationships with clinical and biological variables

2015

Malemedicine.medical_specialtySettore MED/09 - Medicina InternaHepatologybusiness.industryFatty liverNon alcoholicHeartmedicine.diseaseNon-alcoholic fatty liver disease fibrosis obesityGastroenterologyDisease severityLiverFibrosisNon-alcoholic Fatty Liver DiseaseInternal medicinemedicineHumansFemalebusinessPericardiumUltrasonographyJournal of Hepatology
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