Search results for " opera"

showing 10 items of 3606 documents

Metabolic signatures across the full spectrum of non-alcoholic fatty liver disease.

2022

Funder: European Commission

ALTtype 2 diabetes mellitusROC receiving operator characteristicaspartate aminotransferaseHSDLDL low-density lipoproteinUHPLC ultrahigh-performance liquid chromatographyROCHCCNon-alcoholic steatohepatitisGCPCANASHGastroenterology2-HB 2-hydroxybutanoic acid; 3-HB 3-hydroxybutanoic acid; ALT alanine aminotransferase; AST aspartate aminotransferase; CE cholesterol ester; Cer ceramide; FFA free fatty acid; FLIP Fatty Liver Inhibition of Progression; Fibrosis; GC gas chromatography; HCC hepatocellular carcinoma; HSD honest significant difference; LC lipid cluster; LDL low-density lipoprotein; LM lipid and metabolite; LMC lipid metabolite and clinical variable; LPC lysophosphatidylcholine; Lipidomics; Mass spectrometry; Metabolomics; NAFL non-alcoholic fatty liver; NAFLD non-alcoholic fatty liver disease; NAS NASH activity score; NASH non-alcoholic steatohepatitis; NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network; NRR non-rejection rate; Non-alcoholic steatohepatitis; PC(O) ether PC; PC phosphatidylcholine; PCA principal component analysis; PE phosphatidylethanolamine; QTOFMS quadrupole-time-of-flight mass spectrometry; ROC receiving operator characteristic; SAF steatosis activity and fibrosis; SM sphingomyelin; T2DM type 2 diabetes mellitus; TG triacylglycerol; UHPLC ultrahigh-performance liquid chromatographySAFSAF steatosis activity and fibrosisLM lipid and metabolitehonest significant differenceHSD honest significant differenceTG triacylglycerolnon-rejection ratecholesterol esterPCPEGC gas chromatographyfree fatty acidFLIPNASH non-alcoholic steatohepatitisNIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkBIOMARKERST2DMPE phosphatidylethanolamineLDLlipidNAFLDFFA free fatty acid2-HBMetabolomicsNAFL non-alcoholic fatty liverLMCphosphatidylcholineScience & TechnologySM sphingomyelinGastroenterology & HepatologyMass spectrometryactivitynutritional and metabolic diseasesT2DM type 2 diabetes mellitusACIDSreceiving operator characteristicdigestive system diseasesquadrupole-time-of-flight mass spectrometryLC lipid clusterlow-density lipoproteinNAS2-HB 2-hydroxybutanoic acidNAS NASH activity scoreQTOFMSether PCNRRSCORING SYSTEMprincipal component analysisgas chromatographyLC2-hydroxybutanoic acidPROGRESSIONAST aspartate aminotransferaseLMPC phosphatidylcholinePC(O)MARKERSUHPLCsteatosisTOOLImmunology and AllergyINSULIN-RESISTANCECerSMFatty Liver Inhibition of Progressionhepatocellular carcinoma2-HB 2-hydroxybutanoic acid NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network NRR non-rejection rate Non-alcoholic steatohepatitis PC(O) ether PC PC phosphatidylcholine PCA principal component analysis PE phosphatidylethanolamine QTOFMS quadrupole-time-of-flight mass spectrometry ROC receiving operator characteristic SAF steatosis activity and fibrosis SM T2DM type 2 diabetes mellitus TG triacylglycerol UHPLC ultrahigh-performance liquid chromatographyultrahigh-performance liquid chromatographyCELPC3-HBNAFLnon-alcoholic fatty liverTGtriacylglycerolNRR non-rejection rateLife Sciences & BiomedicineNAFLD non-alcoholic fatty liver diseaseFLIP Fatty Liver Inhibition of Progressionalanine aminotransferasemetaboliteCer ceramideCE cholesterol estersphingomyelinlysophosphatidylcholineand fibrosisALT alanine aminotransferaseInternal MedicineceramideNational Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkAST3-HB 3-hydroxybutanoic acidQTOFMS quadrupole-time-of-flight mass spectrometryPCA principal component analysisLPC lysophosphatidylcholineHepatologynon-alcoholic fatty liver diseaseand clinical variablePC(O) ether PC3-hydroxybutanoic acidFibrosisNASH activity scoreNIDDK NASH-CRNlipid clusterlipid and metabolitephosphatidylethanolamineLipidomicsLMC lipid metabolite and clinical variableFFAHCC hepatocellular carcinomaJHEP reports : innovation in hepatology
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Binding mode analysis of ABCA7 for the prediction of novel Alzheimer's disease therapeutics

2021

Graphical abstract

ATP Adenosine-triphosphateNBD nucleotide binding domainGSH reduced glutathionePolypharmacologyAlzheimer’s disease (AD)ATP-binding cassette transporterHTS high-throughput screeningBiochemistryABCA7Structural BiologyPLIF protein ligand interactionMSD membrane spanning domainPDB protein data bankTM transmembrane helixABC ATP-binding cassetteMultitarget modulation (PANABC)RMSD root mean square distanceABC transporter (ABCA1 ABCA4 ABCA7)Computer Science ApplicationsMOE Molecular Operating EnvironmentPharmacophoreSNP single-nucleotide polymorphismBiotechnologyResearch ArticleBBB blood-brain barrierBiophysicsDrug designComputational biologyBiologyAD Alzheimer’s diseasePET positron emission tomographyIC intracellular helixAPP amyloid precursor proteincryo-EM cryogenic-electron microscopyGeneticsHomology modelingBinding siteRational drug design and developmentComputingMethodologies_COMPUTERGRAPHICSNBD-cholesterol 7-nitro-2-13-benzoxadiazol-4-yl-cholesterolTransporterPSO particle swarm optimizationPET tracer (PETABC)ECD extracellular domainR-domain/region regulatory domain/regionABCA1biology.proteinEH extracellular helixTP248.13-248.65BODIPY-cholesterol 44-difluoro-4-bora-3a4a-diaza-s-indacene-cholesterolComputational and Structural Biotechnology Journal
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Shared Leadership Regulates Operational Team Performance in the Presence of Extreme Decisional Consensus/Conflict: Evidences from Business Process Re…

2019

This study focuses on decision-making within operational teams. Grounding our argumentation on group decision-making literature, we argue that adverse behavior patterns may affect the way in which consensus is achieved within the team, and that team performance has an inverted U-shaped relationship with the level of consensus. Then, by relying on leadership literature, we pose the hypothesis that the level of shared leadership inside the group moderates this U-shaped relationship. To empirically test our literature-based argumentation, we use longitudinal data collected in the years 2014 and 2015 from business process reengineering projects, each lasting three months, conducted by 141 maste…

Abilene Paradox Performance Business Process Reengineering Group Decision-Making Groupthink Operational Team Shared-Leadership
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A heuristic algorithm for project scheduling with splitting allowed

1996

In this article, we analyze the precedence diagramming method, the only published algorithm for time-only project scheduling with activity splitting allowed. The criteria used in this method (forward and backward pass computations) for deciding when an activity has to be interrupted are shown to be invalid in some situations. We look into the causes of these failures and propose new formulae that always provide feasible solutions. The new algorithm has been tested on 240 randomly generated problems ranging up to 600 activities and 7,200 precedence relationships, resulting in an average deviation from optima of less than 1 percent.

Absolute deviationMathematical optimizationControl and OptimizationPrecedence diagram methodArtificial IntelligenceComputer Networks and CommunicationsComputer scienceComputationRangingManagement Science and Operations ResearchAlgorithmSoftwareInformation SystemsJournal of Heuristics
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The vibrational levels of methane obtained from analyses of high-resolution spectra

2006

International audience; Methane and its tetrahedral isotopologues are spherical-top molecules whose high-resolution rovibrational spectra can only be analyzed in detail, thanks to sophisticated symmetry-adapted tensorial models. However, the effective Hamiltonian parameters of such models do not give direct access to the positions of the vibrational sublevels. In this paper, we present a calculation of the vibrational level positions for 12CH4, 13CH4, 12CD4 and 13CD4 performed using the effective Hamiltonian parameters obtained through recent analyses. We also include the results of a re-analysis of the octad system of 12CH4 performed with a higher order of the development which slightly im…

Absorption spectroscopy01 natural sciencesSpectral lineMethanesymbols.namesakechemistry.chemical_compoundvibrational levels and sublevels0103 physical sciencesIsotopologuepolyads010303 astronomy & astrophysicsSpectroscopyPhysics[PHYS.PHYS.PHYS-AO-PH]Physics [physics]/Physics [physics]/Atmospheric and Oceanic Physics [physics.ao-ph]Radiation010304 chemical physicsmethanepotential surfaceRotational–vibrational spectroscopyAtomic and Molecular Physics and OpticsMathematical Operatorschemistry[ PHYS.PHYS.PHYS-AO-PH ] Physics [physics]/Physics [physics]/Atmospheric and Oceanic Physics [physics.ao-ph]TetrahedronsymbolsAtomic physicsHamiltonian (quantum mechanics)tensorial formalism
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Liquid−Liquid Equilibria for the System 1-Methyl Propyl Ethanoate (1) + Acetic Acid (2) + Water (3) at (283.15 and 323.15) K

2009

Liquid−liquid equilibrium (LLE) data for the system 1-methyl propyl ethanoate + acetic acid + water were measured at temperatures of (283.15 and 323.15) K. The temperature influence on the LLE data is very small in the temperature range studied. The NRTL and UNIQUAC models were used to correlate the data for both ternary systems. The interaction parameters obtained from both models successfully correlated the equilibrium compositions.

Acetic acidchemistry.chemical_compoundUNIQUACChromatographychemistryGeneral Chemical EngineeringNon-random two-liquid modelAnalytical chemistryLiquid liquidGeneral ChemistryAtmospheric temperature rangeTernary operationJournal of Chemical & Engineering Data
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'Opera e declamazione teatrale in Italia nel Diciottesimo secolo. Convergenze e problemi'

2014

The fulfilment of the operatic reform, managed by Christoph Willibald Gluck and his librettist Ranieri Calzabigi in 1760s’ Vienna, is a well-known topic. This event, whose seeds date back to the 1740s, has been examined according to theatrical and literary experiences in France and Italy. However, the question of acting influence on opera can be reconsidered at the light of the latest discovery of symbols collected and labelled as drammatica – metodo italiano. Engraved in some writings, this set of signs is often connected to music and offers the matter for a new critical survey about the discourse on music declamation before and after Calzabigi. From the 1830s onwards the theory of acting …

Acting's Symbols Opera Ranieri Calzabigi Music DeclamationSettore L-ART/07 - Musicologia E Storia Della Musica
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Potential of phosphonium-based ionic liquids to purify 1-propanol from water by liquid–liquid extraction at mild conditions

2022

Abstract In order to reduce the environmental of the separation of 1-propanol from water in a residual industry stream for its reuse, the capability as solvents of two different trihexyl(tetradecyl)phosphonium ionic liquids (ILs) – trihexyl(tetradecyl)phosphonium chloride ([TDTHP][Cl]) and trihexyl(tetradecyl)phosphonium bromide ([TDTHP][Br])-, was studied. The liquid–liquid equilibria data for both ternary systems, {water + 1-propanol + [TDTHP][Cl]} and {water + 1-propanol + [TDTHP][Br]} at different mild work temperatures, (283.2, 303.2 and 323.2) K, and atmospheric pressure were measured. The thermodynamic parameters for both ternary systems at different work conditions were obtained by …

Activity coefficientChemistryAtomic and Molecular Physics and Opticschemistry.chemical_compoundBromideLiquid–liquid extractionIonic liquidNon-random two-liquid modelPhysical chemistryGeneral Materials SciencePhosphoniumPhysical and Theoretical ChemistrySolubilityTernary operationThe Journal of Chemical Thermodynamics
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Prediction of Maxwell – Stefan diffusion coefficients in polymer – multicomponent fluid systems

2014

Abstract Calculations of mass fluxes in multicomponent fluids based on the system of generalized Maxwell–Stefan equations (GMSE) is preferably used because Maxwell–Stefan (M–S) diffusion coefficients are symmetrical and have a clear physical meaning, as they reflect the binary friction forces between compounds in the system. For the calculation of the mass transport of a multicomponent fluid in the polymer basing on GMSE, it is necessary to have M–S diffusion coefficients. This paper proposes a method that allows their calculation using widely available self-diffusion coefficients and binary diffusion coefficients for infinitely diluted mixtures. The proposed method was compared with the me…

Activity coefficientMolar concentrationChemistryDiffusionThermodynamicsFiltration and SeparationMole fractionBiochemistrychemistry.chemical_compoundMaxwell–Stefan diffusionVinyl acetateGeneral Materials ScienceDiffusion; Multicomponent; Polymer; Free volume; Maxwell–StefanPhysical and Theoretical ChemistryTernary operationMass fractionJournal of Membrane Science
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Phase equilibrium for the systems diisopropyl ether, isopropyl alcohol+2,2,4-trimethylpentane and +n-heptane at 101.3kPa

2010

Abstract Consistent vapour–liquid equilibrium data for the ternary systems diisopropyl ether + isopropyl alcohol + 2,2,4-trimethylpentane and diisopropyl ether + isopropyl alcohol + n-heptane are reported at 101.3 kPa. The vapour–liquid equilibrium data have been correlated by Wilson, NRTL and UNIQUAC equations. The ternary systems do not present ternary azeotropes.

Activity coefficientTernary numeral systemUNIQUACGeneral Chemical EngineeringGeneral Physics and AstronomyThermodynamicsIsopropyl alcoholchemistry.chemical_compoundchemistryNon-random two-liquid modelDiisopropyl etherOrganic chemistry224-TrimethylpentanePhysical and Theoretical ChemistryTernary operationFluid Phase Equilibria
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