Search results for " organic"
showing 10 items of 5145 documents
Salts of 5-amino-2-sulfonamide-1,3,4-thiadiazole, a structural and analog of acetazolamide, show interesting carbonic anhydrase inhibitory properties…
2015
Three salts of 5-amino-2-sulfonamide-1,3,4-thiadiazole (Hats) were prepared and characterized by physico-chemical methods. The p-toluensulfonate, the methylsulfonate, and the chlorhydrate monohydrate salts of Hats were evaluated as carbonic anhydrase (CA, EC 4.2.1.1) inhibitors (CAIs) and as anticonvulsants and diuretics, since many CAIs are clinically used as pharmacological agents. The three Hats salts exhibited diuretic and anticonvulsant activities with little neurotoxicity. The human (h) isoforms hCA I, II, IV, VII, IX, and XII were inhibited in their micromolar range by these salts, whereas pathogenic beta and gamma CAs showed similar, weak inhibitory profiles.
Transformacja połączeń rtęć - substancje humusowe przy udziale Pleurotus ostreatus
2013
Studio teorico sul confinamento delle azidi di metalli alcalino-terrosi nella cavità di un aggregato tubolare ciclopeptidico
2008
Cross-Linked Thiazolidine Network as Support for Palladium: A New Catalyst for Suzuki and Heck Reactions
2015
A thiazolidine-based material was used for the first time as support for palladium. The support was prepared by starting from a highly cross-linked thiazolium-based material, obtained by radical oligomerization of a bisvinylthiazolium dibromide salt in the presence of 3-mercaptopropyl-modified silica SBA-15. Palladium was immobilized by treatment with tetrachloropalladate salt. Reduction with sodium borohydride afforded a thiazolidine-based material that acted as ligands for the Pd species. The thiazolidine-based palladium catalyst was fully characterized and, working in only 0.1 mol% amount, displayed good activity in the Suzuki-Miyaura and in the Heck reactions. Several biphenyl and alken…
Phosphorus-Chalcogen Ring Expansion and Metal Coordination
2017
The reactivity of 4-membered (RPCh)2 rings (Ch = S, Se) that contain phosphorus in the +3 oxidation state is reported. These compounds undergo ring expansion to (RPCh)3 with the addition of a Lewis base. The 6-membered rings were found to be more stable than the 4-membered precursors, and the mechanism of their formation was investigated experimentally and by density functional theory calculations. The computational work identified two plausible mechanisms involving a phosphinidene chalcogenide intermediate, either as a free species or stabilized by a suitable base. Both the 4- and 6-membered rings were found to react with coinage metals, giving the same products: (RPCh)3 rings bound to the…
Exploiting the Potential of New Coordination Frameworks for Technological Applications – from Temperature Sensing to Magnetic Storage
2022
Esta tesis es sobre el diseño, síntesis y caracterización de nuevos Polimeros de Coordinación (CPs), porosos o no, que muestran propiedades magnéticas y/o ópticas, para explotar su potencial en diversas aplicaciones tecnológicas. El diseño de estos materiales requiere una atención particular en la selección de los componentes básicos moleculares, los ligandos orgánicos y los nodos metálicos. Para construir CP con diferentes propiedades físicas, se han elegido derivados de carboxilato y anilato. En particular, el ácido 1,3,5-bencentricarboxílico (H3BTC, ácido trimésico), un ligando bioacompatible que permite construir polimeros organometálicos 3D robustos, y el 3,6-ditriazolil-2,5 -dihidroxi…
Effect of seasonality on physico-chemical and microbiological properties of nicastrese milk and artisanal cheese
2021
ABSTRACT Nicastrese is an indigenous Italian goat breed reared in the Calabria region under semi-extensive practices. From January to June, the milk yield of 400 multiparous Nicastrese goats was evaluated. In addition, tank milk and ripened cheese samples were subjected to physico-chemical and microbiological analyses with the aim to assess the effect of the seasonality on quality parameters. The volatile organic compounds profile of the ripened Nicastrese cheese samples was evaluated. Results showed that the seasonality had a significant effect on milk fat, lactose, urea, citric acid contents and acidity. Microbiological analysis of tank milk samples revealed variability among the differen…
Formation of microbial organic carbonates during the Late Jurassic from the Northern Tethys (Amu Darya Basin, Uzbekistan): implications for Jurassic …
2020
23 pages; International audience; The Late Jurassic was a period of major global carbon cycle perturbations with episodes of anoxia leading to regional accumulation of organic matter in sediments worldwide. The Tubiegatan section (SW Gissar Mountains, Uzbekistan) located in the Northern Tethys, shows atypical organic-rich limestone and marl deposits (up to 6% of total organic carbon) marked by pronounced negative excursions of δ13Ccarb (amplitude of ca. 12‰) and δ13Corg (amplitude of ca. 4‰) recorded during the Middle Oxfordian (Transversarium Zone). A transdisciplinary approach including sedimentology, palynofacies characterization, mineralogy, organic and inorganic geochemistry was carrie…
Chemical composition and microencapsulation suitability of sumac (Rhus coriaria L.) fruit extract
2021
Sumac (Rhus coriaria L.), a spice obtained by grinding whole sumac berries, is a complex natural product with a plethora of biological activities that can be favorably explored in nutraceutical and pharmaceutical fields. Sicilian sumac is herein chemically investigated by means of a combined NMR/HR MS-based profiling. A hydroalcoholic extract was prepared and its complexity unraveled following fractionation in an alcoholic and an aqueous fraction. The 1H-NMR spectrum of this latter fraction was dominated by the signals of gallic acid and its derivatives, whereas HR MS and HR MS/MS analyses highlighted the diversity in malic acid derivatives. Gallotannins and galloyl flavonol glycosides with…
Response of Soil Microbial Communities to Iron-Porphyrin Catalytic Amendments.
2010
Intensive agricultural practices strongly increase CO2 emission from soil. Synthetic metal-porphyrins were shown to significantly decreased CO2 emission from soil due to an in-situ catalysis of oxidative polymerization of soil organic matter. This research aimed to assess the effects of iron-porphyrin (POR) amendments on soil microbial communities in three arable soils under wheat and maize cropping located in Naples, Turin and Piacenza, characterized by different pedological and climatic conditions. Bulk-soil and rhizo-soil were sampled during 4 years and the microbial groups directly involved in organic matter (OM) mineralization and in key processes of the nitrogen cycle were examined. M…