Search results for " organization"

Association between WHO cut-offs for childhood overweight and obesity and cardiometabolic risk

2012

AbstractObjectiveTo examine the association between cardiovascular risk and childhood overweight and obesity using the BMI cut-offs recommended by the WHO.DesignChildren were classified as normal weight, overweight and obese according to the WHO BMI-for-age reference. Blood pressure, lipids, glucose, insulin, homeostasis model assessment–insulin resistance (HOMA-IR) and uric acid levels were compared across BMI groups. ANOVA and tests of linearity were used to assess overall mean differences across groups. Crude and adjusted odds ratios were calculated for adverse plasma levels of biochemical variables.SettingPaediatric care centres.SubjectsChildren (n149) aged 8–18 years.ResultsAbout 37 %,…

Prevalence and impact of metabolic syndrome on hospital outcomes in acute myocardial infarction.

2005

The impact of metabolic syndrome after acute myocardial infarction (AMI) has not yet been studied. In a population-based sample of patients with AMI, we sought to determine the prevalence of metabolic syndrome in patients with AMI, its impact on hospital outcomes, and to assess the relative influence of each of the components of the National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III definition of metabolic syndrome on the risk of death and heart failure.A total of 633 unselected, consecutive patients hospitalized with AMI were categorized according to the NCEP ATP III metabolic syndrome criteria (presence of/=3 of the following: hyperglycemia; triglyceride level/=…

A Non-Reductionist Physiologism: Nietzsche on Body, Mind and Consciousness

2013

This paper addresses the following questions from the point of view of Nietzsche’s philosophy: What is the mind, and which kind of relationship does it hold to the body? Accordingly, the aim of this paper is to show that Nietzsche’s philosophy suggested a view of the mind that allows to outline an alternative stance to both mentalism and physicalism, as well as to both dualism and reductionism. It is argued that Nietzsche’s rehabilitation of the body as the specific seat of the mind in opposition to the Cartesian supremacy of the Ego still is of a great interest for contemporary philosophy, since it is not equivalent either to a reversed form of Cartesian dualism or to a physicalist reducti…

Gada as an Integrative Factor of Political Organization

1994

Impact of orphan drugs on Latvian budget

2016

Background Number of orphan medicinal products on the market and number of rare disease patients, taking these usually expensive products, are increasing. As a result, budget impact of orphan drugs is growing. This factor, along with the cost-effectiveness of orphan drugs, is often considered in the reimbursement decisions, directly affecting accessibility of rare disease therapies. The current study aims to assess the budget impact of orphan drugs in Latvia. Methods Our study covered a 5-year period, from 2010 to 2014. Impact of orphan drugs on Latvian budget was estimated from the National Health Service’s perspective. It was calculated in absolute values and relative to total pharmaceuti…

The relation between workload and personal well-being among university professors

2019

The aim of the present study was to explore the level of perceived workload of university professors and to evaluate related psychosocial risks, such as addiction to work, psychological distress, and work–life conflicts. A total of 252 professors, balanced for gender (Mean age = 48.1; DS: 5.1) from 10 different universities across Europe participated in the research. Participants completed the University’s Work Environment Survey, the Dutch Workaholism Scale, and The General Health Questionnaire. The results showed that workload, when linked to bureaucratic university practices, is a predisposing factor to a negative perception of work-related well-being among university professors.

L'evolució històrica de la psicologia del treball i de les organitzacions

2010

El món organitzacional ha esdevingut l'eix vertebrador de la Psicologia del treball, des del sistema gremial al sistema fabril, que reunia les característiques de veritables organitzacions industrials. Les notes que caracteritzen el procés són: la mentalitat racional, la mecanització de la fabricació i la utilització del vapor com nova energia aplicable a la indústria. A més, la mecanització tindria efectes sobre l'organització del treball, en l'extremar la diferenciació de funcions i la divisió de tasques. Taylor, des de l'enginyeria, introduí una organització científica del treball per millorar els sistemes i els llocs laborals. Amb el mateix objectiu, orientat a millorar l'administració …

Offshore Assets in the Transition from ‘Traditional Business Practice’ to ‘Connected Business Eco-systems’

2020

In many industrial sectors we have already begun to see how new business ecosystems gradually emerge turning the traditional business practices upside down. Particularly within relatively conventional sectors, such as upstream oil and gas (O&G) and land-based process industry, we expect to see substantial changes in the years to come. In this paper, we elaborate on principal challenges related to major structural changes and core technology platforms for the oil industry identifying critical features and elaborating on emerging operational principles. This is based on a critical review of latest industry conditions and practices that are targeted towards the creation of new business models …

2021

The increasing digitalization of economies has highlighted the importance of digital transformation and how it can help businesses stay competitive in the market. However, disruptive changes not only occur at the company level; they also have environmental, societal, and institutional implications. This is the reason why during the past two decades the research on digital transformation has received growing attention, with a wide range of topics investigated in the literature. The following aims to provide insight regarding the current state of the literature on digital transformation (DT) by conducting a systematic literature review. An analysis of co-occurrence using the software VOSviewe…

Macrophage-Specific Lipid-Based Nanoparticles Improve Cardiac Magnetic Resonance Detection and Characterization of Human Atherosclerosis

2009

ObjectivesWe sought to determine whether gadolinium (Gd)-containing lipid-based nanoparticles (NPs) targeting the macrophage scavenger receptor-B (CD36) improve cardiac magnetic resonance (CMR) detection and characterization of human atherosclerosis.BackgroundGd-containing lipid-based NPs targeting macrophages have improved MR detection of murine atherosclerosis.MethodsGadolinium-containing untargeted NPs, anti-CD36 NPs, and nonspecific Fc-NPs were created. Macrophages were incubated with fluorescent targeted and nontargeted NPs to determine uptake via confocal microscopy and inductively coupled plasma mass spectroscopy (ICP-MS) quantified Gd uptake. Human aortic specimens were harvested at…