Search results for " pathophysiology"
showing 2 items of 12 documents
Alcohol, Cannabinoids and Nicotine in liver pathophysiology
2017
The liver can be affected by a wide range of therapeutic and environmental chemicals and here we want to provide a summary of the complex effects of alcohol, cannabinoids and nicotine on liver function. Alcohol is the most important agent that produces liver injury, manifesting as alcoholic fatty liver disease. In addition, it is one of the main etiologic agents for hepatocellular carcinoma development. Studies reviewed in this article regarding cannabinoids, show that Δ9-THC does not produce any harmful effects on the liver, while cannabidiol has hepatoprotective effects in ischemia/reperfusion and alcohol-induced liver injuries. The liver is negatively affected by nicotine exposure, but s…
Panic disorder, anxiety, and cardiovascular diseases
2014
Different data indicate that psychological and/or emotional disorders may play an important role in the natural history of heart diseases. Although the major evidence is that related to depression, epidemiological data would indicate that anxiety and panic disorders are highly represented in cardiac patient, thus influencing mortality and morbidity. The diagnosis of panic disorder in patients with chest pain is crucial to a correct therapeutic approach, as well as to reduce the risks and costs of inappropriate treatments. Anxiety and panic may accelerate different direct and indirect processes involved in the pathogenesis of cardiovascular diseases: lifestyle risk factors, arterial hyperten…