Search results for " phytochemical"

showing 10 items of 46 documents

Phytochemical profile and antioxidative properties of Plinia trunciflora fruits: A new source of nutraceuticals.

2020

Abstract This study evaluated the polyphenol profile and the antioxidative properties of Plinia trunciflora (O. Berg) Kausel fruits. Folin-Ciocalteau and pH-jumping methods indicated that these berries are a major source of antioxidant polyphenols (1201.05 mg GAE/100 g FW), particularly anthocyanins. HPLC-DAD-ESI-MS/MS analysis identified cyanidine glycosides as the main components. Flavon-3-ols and hydrolysable-tannins were also found. CAA assay showed that extracts of P. trunciflora fruits prevent lipid peroxidation in HepG2 cells with higher efficacy than other colourful fruits (CAA50 935.25 mg FW/mL cell medium). Moreover, our results suggested that the observed antioxidant protection i…

AntioxidantDPPHmedicine.medical_treatmentMyrtaceaePhytochemicals01 natural sciencesAntioxidantsAnalytical ChemistryAnthocyaninsLipid peroxidationchemistry.chemical_compoundTandem Mass SpectrometrySettore BIO/10 - BiochimicaFood scienceChromatography High Pressure LiquidChromatographyABTSbiologyChemistryfood and beverages04 agricultural and veterinary sciencesGeneral MedicineHep G2 CellsJaboticaba040401 food scienceUp-RegulationPhytochemicalHigh Pressure LiquidAntioxidant enzymesMyrciaria truncifloraPlinia0404 agricultural biotechnologyNutraceuticalmedicineHumansGlutathione PeroxidasePlant ExtractsSuperoxide DismutaseAntioxidant enzyme010401 analytical chemistryPolyphenolsbiology.organism_classification0104 chemical sciencesPolyphenolFruitDietary SupplementsLipid PeroxidationAnthocyanins; Antioxidant enzymes; Cellular antioxidant activity (CAA); Jaboticaba; Myrciaria trunciflora; Antioxidants; Chromatography High Pressure Liquid; Dietary Supplements; Fruit; Glutathione Peroxidase; Hep G2 Cells; Humans; Lipid Peroxidation; Myrtaceae; Phytochemicals; Plant Extracts; Polyphenols; Superoxide Dismutase; Tandem Mass Spectrometry; Up-RegulationCellular antioxidant activity (CAA)Food ScienceFood chemistry
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Cooking influence on physico-chemical fruit characteristics of eggplant (Solanum melongena L.)

2016

Physico-chemical traits of three eggplant genotypes ("Tunisina", "Buia" and "L 305") were evaluated before and after two cooking treatments (grilling and boiling). Different genotypes revealed different changes after cooking, with "Tunisina" showing a better retention of phytochemicals with respect to other two genotypes. The main physical phenomena were water loss during grilling, and dry matter loss after boiling. Chlorogenic acid, the main phenolic in eggplant, resulted higher in grilled samples, while delphinidin glycosides resulted more retained in boiled samples. Glycoalkaloids, thiols and biogenic amines were generally stable, while 5-hydroxy-methyl-furfural was found only in grilled…

AntioxidantMagnetic Resonance Spectroscopymedicine.medical_treatmentPhytochemicalsSettore AGR/13 - Chimica AgrariaFood chemistryEggplantPhytochemical01 natural sciencesAntioxidantsAnalytical Chemistrychemistry.chemical_compound0404 agricultural biotechnologyChlorogenic acidPhenolsBotanymedicineDry matterPhenolsFood scienceCookingSolanum melongenaAntioxidants; Cooking; Eggplant; NMR relaxometry; Phenols; Antioxidants; Chlorogenic Acid; Fruit; Magnetic Resonance Spectroscopy; Phenols; Phytochemicals; Solanum melongena; Food Science; Analytical Chemistry; Medicine (all)chemistry.chemical_classificationbiologyPhenolMedicine (all)010401 analytical chemistryfood and beveragesGlycoside04 agricultural and veterinary sciencesGeneral Medicinebiology.organism_classification040401 food science0104 chemical scienceschemistryFruitNMR relaxometryDelphinidinSolanumAntioxidantChlorogenic AcidFood Science
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Betacyanins as phenol antioxidants. Chemistry and mechanistic aspects of the lipoperoxyl radical-scavenging activity in solution and liposomes.

2009

Reaction kinetics of betanin and its aglycone betanidin towards peroxyl radicals generated from the azo-initiated oxidation of methyl linoleate in methanol, and of a heterogeneous aqueous/soybean phosphatidylcholine liposomal system, were studied by monitoring formation of linoleic acid hydroperoxides and consumption of the pigments. Betanin was a weak retarder in methanol, and an effective chain breaking antioxidant in the liposomal model, indicating that kinetic solvent effects and partition in lipid bilayers may affect its activity. Betanidin behaved as a chain terminating antioxidant in both models. Kinetic parameters characterizing peroxyl radical-scavenging activity showed that betani…

Antioxidantmedicine.medical_treatmentLipid Bilayersalpha-TocopherolBiochemistryChemical kineticsLinoleic Acidchemistry.chemical_compoundStructure-Activity RelationshipReaction rate constantSettore BIO/10 - BiochimicamedicineBetacyaninsOrganic chemistryChromatography High Pressure LiquidBetaninAqueous solutionMolecular StructureMethanolWaterDrug SynergismGeneral MedicineFree Radical ScavengersSolutionsAglyconechemistryLinoleic Acidsbetacyanins betanin betanidin lipid peroxides liposomes antioxidant phytochemicalsSpectrophotometryLiposomesPhosphatidylcholinesSolventsMethanolBetacyaninsLipid PeroxidationOxidation-ReductionFree radical research
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Prophylaxis of Non-communicable Diseases: Why fruits and vegetables may be better chemopreventive agents than dietary supplements based on isolated p…

2019

The World Health Organization (WHO) report from 2014 documented that non-communicable socalled civilization diseases such as cardiovascular disease, chronic respiratory diseases, cancer or type 2 diabetes are responsible for over 50% of all premature deaths in the world. Research carried out over the past 20 years has provided data suggesting that diet is an essential factor influencing the risk of development of these diseases. The increasing knowledge on chemopreventive properties of certain food ingredients, in particular, those of plant origin, opened the discussion on the possibility to use edible plants or their active components in the prevention of these chronic diseases. Health-pro…

Antioxidants; Bioactive phytochemicals; Cancer; Chemoprevention; Civilization diseases; Flavonoids; Food synergyantioxidantPhytochemicalsRespiratory Tract DiseasesActive componentsDiseaseChemopreventionWorld healthAntioxidants03 medical and health sciencesbioactive phytochemical0302 clinical medicineFunctional foodNeoplasmsVegetablesDrug DiscoveryHumansMedicinecivilization diseaseflavonoidNoncommunicable Diseases030304 developmental biologyCancer2. Zero hungerPharmacologyFlavonoids0303 health sciencesTraditional medicineFood synergyHuman organismbusiness.industryBioactive phytochemicalsDiet3. Good healthDiabetes Mellitus Type 2Cardiovascular DiseasesFruit030220 oncology & carcinogenesisFruits and vegetablesDietary SupplementsEdible plantsCivilization diseasesCritical assessmentbusiness
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Indicaxanthin inhibits NADPH oxidase (NOX)-1 activation and NF-κB-dependent release of inflammatory mediators and prevents the increase of epithelial…

2014

Dietary redox-active/antioxidant phytochemicals may help control or mitigate the inflammatory response in chronic inflammatory bowel disease (IBD). In the present study, the anti-inflammatory activity of indicaxanthin (Ind), a pigment from the edible fruit of cactus pear (Opuntia ficus-indica, L.), was shown in an IBD model consisting of a human intestinal epithelial cell line (Caco-2 cells) stimulated by IL-1β, a cytokine known to play a major role in the initiation and amplification of inflammatory activity in IBD. The exposure of Caco-2 cells to IL-1β brought about the activation of NADPH oxidase (NOX-1) and the generation of reactive oxygen species (ROS) to activate intracellular signal…

Cell Membrane PermeabilityPyridinesPyridinemedicine.medical_treatmentInterleukin-1betaMedicine (miscellaneous)Nitric Oxide Synthase Type IIIndicaxanthinNADPH OxidaseInflammatory bowel diseaseIntestinal absorptionAntioxidantschemistry.chemical_compoundSettore BIO/10 - BiochimicaInflammation MediatorCaco-2 CellNutrition and DieteticsNADPH oxidasebiologyNF-kappa BNADPH Oxidase 1OpuntiaCell biologyBetaxanthinsCytokineNADPH Oxidase 1EnterocyteAntioxidantmedicine.symptomInflammation MediatorsReactive Oxygen SpecieIndicaxanthinHumanRedox-active phytochemicalInflammationIn vitro modelmedicineHumansIndicaxanthin Betalain pigments Inflammatory bowel disease Redox-active phytochemicalsInterleukin 8Inflammationbusiness.industryInterleukin-6Interleukin-8NADPH OxidasesInflammatory Bowel DiseasesEnzyme ActivationEnterocyteschemistryIntestinal AbsorptionCaco-2Cyclooxygenase 2BetaxanthinFruitImmunologybiology.proteinCaco-2 CellsbusinessReactive Oxygen SpeciesThe British journal of nutrition
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Phytochemical Constituents, Antioxidant Activity, and Toxicity Assessment of the Aerial Part Extracts from the Infraspecific Taxa of Matthiola frutic…

2021

In a project designed to investigate the specific and infraspecific taxa of Matthiola endemic to Sicily (Italy) as new potential sources of bioactive compounds in this work, the infraspecific taxa of Matthiola fruticulosa were studied, namely, subsp. fruticulosa and subsp. coronopifolia. HPLC–PDA/ESI–MS and SPME–GC/MS analyses of hydroalcoholic extracts obtained from the aerial parts of the two subspecies led to the detection of 51 phenolics and 61 volatile components, highlighting a quite different qualitative–quantitative profile. The antioxidant properties of the extracts were explored through in vitro methods: 1,1-diphenyl-2-picrylhydrazyl (DPPH), reducing power and Fe2+ chelating activ…

DPPHPharmaceutical Sciencebiological activityBrine shrimpMatthiolaSubspecies01 natural sciencesAnalytical Chemistry03 medical and health scienceschemistry.chemical_compoundQD241-441Biological activity; Chemical composition; Matthiola fruticulosa; Native plants; Natural resource; Sicily; Animals; Antioxidants; Artemia; Brassicaceae; Larva; Phytochemicals; Plant Extracts; Sicily; Toxicity Tests.Drug Discoverychemical compositionBioassaySettore BIO/15 - Biologia FarmaceuticaPhysical and Theoretical ChemistrySicily030304 developmental biology0303 health sciencesbiologyTraditional medicineSettore BIO/02 - Botanica Sistematica<i>Matthiola fruticulosa</i>Organic ChemistryBrassicaceaenative plantsnative plantbiology.organism_classificationnatural resource0104 chemical sciences010404 medicinal & biomolecular chemistrychemistryPhytochemicalChemistry (miscellaneous)Matthiola fruticulosaMolecular MedicineArtemia salinaMolecules
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The Sicilian wild cabbages as biological resources: taxonomic update and a review on chemical constituents and biological activities

2020

Considering the growing interest that wild brassicas have as sources of bioactive molecules as well as a genetic resource, the authors review and update the taxonomy of Brassica sect. Brassica, limited to the native flora of Sicily, an island considered to be an active diversification center for the group of species of the aforementioned section. Regarding the taxonomic aspects, Brassica tardarae is here considered a subspecies of B. rupestris; the distinction at the subspe- cific level of B. raimondoi, a critical taxon included in B. incana, is also confirmed. In addition, two new subspecies are proposed, respectively in B. incana and B. rupestris. The taxonomic information relating to the…

EcologySettore BIO/02 - Botanica SistematicaPhytochemicalsPlant ScienceBiologylanguage.human_languageVascular floraChemical constituentsBrassicaceaelanguageGlucosinolates. SicilySettore BIO/15 - Biologia FarmaceuticaSicilianBrassica sect. BrassicaTaxonomyvascular flora Brassica sect. Brassica Brassicaceae taxonomy phytochemicals glucosinolates. Sicily
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Cactus pear fruit extract exerts anti-inflammatory effects in carrageenin-induced rat pleurisy

2015

Nutritional research has recently shifted from alleviating nutrient deficiencies to chronic disease prevention. In this study activity of cactus pear fruit extract (CPFE) from Opuntia ficus-indica (L.) Mill. has been investigated in carrageenin-induced pleurisy, a rat model of acute inflammation. In our experimental design rat pleurisy was achieved by the injection of 0.2 ml of λ-carrageenin in the pleural cavity. At selected time points, rats were sacrificed; cells recruited in pleura were counted and exudates collected to analyse inflammatory parameters such as NO, PGE2, IL-1β, TNF-α. CPFE (in the range between 5 and 20 g fresh fruit equivalent/kg), orally given 30 min before the injectio…

ExudatePEARmedicine.drug_classIndicaxanthin inflammation phytochemicals oxidative stressInflammationHorticulturePleural cavityBiologyPharmacologymedicine.diseaseAnti-inflammatoryHorticulturemedicine.anatomical_structureFunctional foodPleurisyIn vivoSettore BIO/10 - Biochimicamedicinemedicine.symptom
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Effects on the quality and nutritional traits of wood strawberry fruits in Sicily.

2011

In Sicily, the common woodland strawberry (Fragaria vesca) is spontaneous in the Madonie Mountains (554 m a.s.l.), Nebrodi Mountains (850 m) and Mount Etna (900 m). In this region, the main clone cultivated is ‘Fragolina di Sciacca e Ribera’, named after the towns where the crop originally developed. It is a Junebearing genotype and it is characterized by very small fruits, globose-conical shape, deep red colour, very soft flesh, strong aroma and flavor. Also ever-bearing clones are cultivated in Sicily where they are cropped for many months. Solid soluble content, total titratable acidity, total antioxidant capacity, total polyphenols and anthocyanins content were quantified in berry sampl…

Fragaria vesca mountain fruit quality phytochemicalsSettore AGR/04 - Orticoltura E Floricoltura
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Phytochemical Profile and Antioxidant, Antiproliferative, and Antimicrobial Properties of Rubus idaeus Seed Powder

2022

In the context of the contemporary research on sustainable development and circular economy, the quest for effective strategies aimed at revaluation of waste and by-products generated in industrial and agricultural production becomes important. In this work, an ethanolic extract from red raspberry (Rubus idaeus) seed waste (WRSP) was evaluated for its phytochemical composition and functional properties in term of antioxidative, antiproliferative, and antimicrobial activities. Chemical composition of the extract was determined by both HPLC-ESI-MS/MS and spectrophotometric methods. Phytochemical analysis revealed that flavan-3-ols and flavonols were the major phenolic compounds contained in W…

Health (social science)cellular oxidative stressminimum inhibitor concentrationPlant Scienceagricultural waste; anticancer activity; cellular oxidative stress; minimum inhibitor concentration; phytochemicals; red raspberry; sustainabilityphytochemicalssustainabilityHealth Professions (miscellaneous)MicrobiologySettore CHIM/08 - Chimica Farmaceuticared raspberryanticancer activitySettore BIO/10 - Biochimicaagricultural wasteFood ScienceSettore AGR/16 - Microbiologia Agraria
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