Search results for " positron"
showing 10 items of 140 documents
Minimally invasive secondary cytoreduction plus HIPEC for recurrent ovarian cancer: a case series.
2014
Objective To analyze the feasibility of laparoscopic/robotic secondary cytoreductive surgery and hyperthermic intraperitoneal intra-operative chemotherapy (SCS + HIPEC) in a retrospective series of isolated platinum sensitive recurrent ovarian cancer. Methods We retrospectively evaluated a consecutive series of ovarian cancer patients with isolated platinum sensitive relapse. Isolated relapse was defined as the presence of a single nodule, in a single anatomic site. In all cases the presence of isolated relapse was assessed at pre-operative FDG-PET/CT scan, and confirmed with staging laparoscopy performed immediately before SCS + HIPEC. Results 84 women with platinum sensitive relapse recei…
Positron emission tomography and neoadjuvant therapy of breast cancer
2011
The increasing use of neoadjuvant therapy for breast cancer has led to the development of early surrogate markers of response. Positron emission tomography (PET) allows noninvasive study of fundamental biologic processes in the tumor; furthermore, PET provides various markers to assess tumor response early in the course of therapy. Numerous studies have shown that changes in tumor glucose metabolism during therapy are significantly correlated with final response and patient outcome. Moreover, new PET tracers that are currently being developed or under evaluation, providing specific information on tumor characteristics or receptor expression, will assist the development of new targeted antic…
[11C]choline-PET-guided helical tomotherapy and estramustine in a patient with pelvic-recurrent prostate cancer: local control and toxicity profile a…
2010
[11C]choline positron emission tomograhy can be useful to detect metastatic disease and to localize isolated lymph node relapse after primary treatment in case of prostate-specific antigen failure. In case of lymph node failure in prostate cancer patients, surgery or radiotherapy can be proposed with a curative intent. Some reports have suggested that radiotherapy could have a role in local control of oligometastatic lymph node disease. This is the first reported case of [11C]choline positron emission tomography-guided helical tomotherapy concomitant with estramustine for the treatment of pelvic-recurrent prostate cancer. At 24 months after the end of helical tomotherapy, prostate-specific…
Imaging standardisation in metastatic colorectal cancer: a joint EORTC-ESOI-ESGAR expert consensus recommendation
2022
Background: Treatment monitoring in metastatic colorectal cancer (mCRC) relies on imaging to evaluate the tumor burden. Response Evaluation Criteria in Solid Tumors (RECIST) provide a framework on reporting and interpretation of imaging findings yet offer no guidance on a standardized imaging protocol tailored to mCRC patients. Imaging protocol heterogeneity remains a challenge for the reproducibility of conventional imaging endpoints and is an obstacle for research on novel imaging endpoints. Patients and methods: Acknowledging the recently highlighted potential of radiomics and artificial intelligence (AI) tools as decision support for patient care in mCRC, a multidisciplinary, internatio…
Search for pair production of heavy objects in 4-jet events at sqrt {s}$=130-136 GeV
1996
Results are presented of a search for pair production of heavy objects decaying into four hadronic jets, as expected for example from associated or pair production of MSSM Higgs bosons, hA or H$^+$H$^-$, using a data sample of $5.9\,$pb$^{-1}$ of $e^+ e^-$ collisions at $\sqrt{s}=130$-$136\,{\mathrm {GeV}}$ collected with the DELPHI detector at LEP in November 1995. The data and expectations from standard processes agree after four-jet selections. An analysis based on $b$-tagging finds no hA candidate with high mass. A study optimized to search for H$^+$H$^-$ events with mass in the 40-50$\,{\mathrm{GeV}}/c^2$ range also finds no candidate. Finally a comparison is made with a recent ALEPH a…
A Precise Measurement of the $\tau$ Polarisation at LEP-1
2000
The $\tau$ polarisation has been studied with the ${\rm e^+e^-}\to \tau^+\tau^-$ data collected by the DELPHI detector at LEP in 1993, 1994 and 1995 around the Z resonance firstly through the exclusive decay channels ${\rm e}\nu\bar{\nu}$ , $\mu\nu\bar{\nu}$ , $\pi\nu$ , $\rho\nu$ and ${\rm a}_1\nu$ and secondly with an inclusive hadronic analysis which benefits from a higher efficiency and a better systematic precision. The results have been combined with those previously published on 1990 to 1992 DELPHI data, to produce results which reflect the full LEP-1 statistics. The fit of the $\tau$ polarisation dependence on the production angle yielded the polarisation parameters ${\cal A}_{_{\sc…
Study of dimuon production in photon-photon collisions and measurement of QED photon structure functions at LEP
2001
Muon pair production in the process e+e- -> e+e-mu+mu- is studied using the data taken at LEP1 (sqrt(s) \simeq m_Z) with the DELPHI detector during the years 1992-1995. The corresponding integrated luminosity is 138.5 pb^{-1}. The QED predictions have been tested over the whole Q^2 range accessible at LEP1 (from several GeV^2/c^4 to several hundred GeV^2/c^4) by comparing experimental distributions with distributions resulting from Monte Carlo simulations using various generators. Selected events are used to extract the leptonic photon structure function F_2^\gamma. Azimuthal correlations are used to obtain information on additional structure functions, F_A^\gamma and F_B^\gamma, which orig…
Cross-sections and leptonic forward-backward asymmetries from the Z(0) running of LEP
2000
During 1993 and 1995 LEP was run at 3 energies near the Z $^0$ peak in order to give improved measurements of the mass and width of the resonance. During 1994, LEP operated only at the Z $^0$ peak. In total DELPHI accumulated data corresponding to an integrated luminosity of approximately 116 pb $^{-1}$ . Analyses of the hadronic cross-sections and of the cross-sections and forward-backward asymmetries in the leptonic channels used the most precise evaluations of the LEP energies. In the dimuon channel, events with a photon radiated from the initial state have been used to probe the cross-sections and asymmetries down to PETRA energies. Model independent fits to all DELPHI lineshape and asy…
Measurement of the ZZ cross-section in e(+)e(-) interactions at 183-189 GeV
2001
Measurements of on-shell ZZ production are described, using data collected by DELPHI in 1997 and 1998, at centre-of-mass energies sqrt(s) = 182.6 GeV and 188.6 GeV respectively. Results obtained in each of the final states q qbar q qbar, mu+mu- q qbar, e+e- q qbar, nu nubar q qbar, l+l-l+l-, and nu nubar l+l- are presented. The measured cross-sections for on-shell ZZ production via the tree-level doubly-resonant graphs (NC02) are: sigma_{NC02}(182.6 GeV) = 0.38 +- 0.18 (stat) +- 0.04 (syst) pb, sigma_{NC02}(188.6 GeV) = 0.60 +- 0.13 (stat) +- 0.07 (syst) pb. They are consistent with the Standard Model expectations of 0.25 pb and 0.65 pb at each energy.
Energy dependence of event shapes and of $\alpha_s$ at LEP 2
1999
Infrared and collinear safe event shape distributions and their mean values are determined using the data taken at five different centre of mass energies above M-Z with the DELPHI detector at LEP. From the event shapes, the strong coupling alpha(s) is extracted in O(alpha(s)(2)), NLLA and a combined scheme using hadronisation corrections evaluated with fragmentation model generators as well as using an analytical power ansatz. Comparing these measurements to those obtained at M-Z, the energy dependence (running) of alpha(s) is accessible. The logarithmic energy slope of the inverse strong coupling is measured to be d alpha(s)(-1)/d log(E-cm) = 1.39 +/- 0.34 (stat) +/- 0.17(syst), in good ag…